Clinical trials: Myocardial Reperfusion Injury
Ischemia-reperfusion(I/R), Cardiopulmonarybypass
Mitochondrial Apoptotic Pathway Induced by Myocardial Ischemia-Reperfusion Injury in Human
Background: The cardiomyocytes apoptosis induced by ischemia-reperfusion(I/R) is one of the most important factors in the myocardial I/R injury(MIRI) undergoing cardiac valve replacement with cardiopulmonary bypass(CVRCPB),and…
- Conditions
- Ischemia-reperfusion(I/R), Cardiopulmonarybypass, the Mitochondrial Pathway, Ischemic Postconditioning
- Trial name
- NCT02430116
- Testing
- Ischemic postconditioning
- Where
- China
- Volunteers
- 40 people
- Sponsor
- WANG Yan-bin
Coronary Artery Disease, Valvular Heart Disease
Application of Remote Ischemic Preconditioning in Patients Undergoing Open Heart Surgeries
Strategies for myocardial protection during open heart surgeries are desired. Several experimental studies have shown beneficial effects of remote ischemic preconditioning (RIPC).
- Trial name
- NCT01906918
- Testing
- IRPC, Remote preconditioning
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Campinas, Brazil