Clinical trials: Myomas
Blood Loss, Surgical, Uterine Myoma
Effect of Rectal Misoprostol in Reducing Intra-operative Blood Loss During Myomectomy
A total of 200 women for elective abdominal myomectomy were randomly allocated into two groups. 100 women in experimental group were administered 400ug Misoprostol (2 tablets of Prosotec®) through the rectal route prior to…
- Trial name
- NCT05108597
- Testing
- Misoprostol
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Intrauterine Diseases, Myomas
A New Alternative to Traditional Hysteroscopy
Hysteroscopy is a procedure designed for the diagnosis and the treatment of intra-uterine diseases. The development of smaller hysteroscopes allowed to change the approach to the intra-uterine lesions unifying the diagnostic and…
- Conditions
- Intrauterine Diseases, Myomas, Polyps
- Trial name
- NCT01430208
- Testing
- resectoscopy
- Where
- Italy
- Volunteers
- 401 people
- Sponsor
- Catholic University of the Sacred Heart
Uterine Myomas
Vasopressin Versus Epinephrine in Myomectomy
Uterine myomas (fibroids or leiomyomas) are the most common benign tumor of the female genital tract and the leading indication for hysterectomy.
- Trial name
- NCT01861015
- Testing
- Epinephrine, Vasopressin
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- CHA University
Uterine Leiomyoma, Uterine Fibroid
ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma
A phase 3 multicenter unblinded randomized controlled trial comparing the temporary uterine blood supply occlusion with conventional approach during laparoscopic myomectomy in patients with uterine leiomyoma.
- Conditions
- Uterine Leiomyoma, Uterine Fibroid, Leiomyoma, Uterine, Myoma;Uterus
- Trial name
- NCT04519593
- Testing
- Laparoscopic myomectomy with prior temporary uterine blood supply occlusion, Conventional laparoscopic myomectomy
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Mother and Child Clinic Saint-Petersburg
Myoma;Uterus, Adenomyoma of Uterus
Evaluation of the Feasibility of Using Augmented Reality in Laparoscopic Surgery, by a Clinical Study During Gynecological Laparoscopic Surgical Procedures.
Augmented Reality is a technology that allows surgeons to superimpose virtual images from preoperative imaging onto the endoscopic vision system intraoperatively.
- Trial name
- ENDORA2 (NCT06067971)
- Testing
- Laparoscopic surgery with augmented reality device
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Fibroid Uterus, Abnormal Uterine Bleeding
Prophylactic Tranexamic Acid During Minimally Invasive Myomectomies
This is a Double-blinded randomized placebo-controlled trial based at Eastern Virginia Medical School. Subjects who are identified in clinic having menorrhagia or abnormal Uterine bleeding (AUB) due to uterine fibroids and meet…
- Conditions
- Fibroid Uterus, Abnormal Uterine Bleeding, Myoma;Uterus
- Trial name
- NCT04311073
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Fibroid Uterus, IVF
The Value of Myomectomy in Women With Intramural Myoma Before IVF.
Women with intramural myoma not reaching the endometrial cavity will be randomized to either open myomectomy or no intervention .
- Trial name
- NCT03904368
- Testing
- Open myomectomy, Gonadotropins, Human chorionic gonadotropin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Uterine Myoma, Uterine Fibroid
Comparison of Pain After Uterine Artery Embolization Using Gelatin Microsphere or Tris-acryl Gelatin Microsphere
This study is a prospective and randomized investigation planned to compare pain after uterine artery embolization using Gelatin microsphere or tris-acryl gelatin microsphere in 60 patients with symptomatic fibroids.
- Trial name
- NCT05086770
- Testing
- Gelatin microsphere (Nexsphere™), Embosphere
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Next Biomedical Co., Ltd.
Uterine Myomas, Adenomyosis
Single-port Access Laparoscopic-assisted Vaginal Hysterectomy
Minimally invasive surgery has become the standard treatment for many gynecologic disease processes. In the last decade, numerous studies have demonstrated that laparoscopic approaches to various gynecologic oncology…
- Trial name
- NCT01048931
- Testing
- single-port LAVH
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Endometrial Polyp Benign, Retained Products of Conception
The Use of a Morcellator in Operative Hysteroscopy for Benign Intracavitary Lesions: a Feasibility Study
Polyps, intracavitary myomas and retained products of conception (RPOC) are common benign intracavitary lesions of the uterus and frequently cause abnormal uterine bleeding or pain.
- Conditions
- Endometrial Polyp Benign, Retained Products of Conception, Myoma;Uterus
- Trial name
- NCT05811286
- Testing
- Hysteroscopic morcellation 19 Fr. intrauterine BIGATTI Shaver for uterine intracavitary lesions
- Where
- 2 sites in Belgium
- Volunteers
- 56 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myoma of Uterus
Analgesic Effect of Trigger Point Injection and EMLA for Shoulder Pain in Laparoscopic Hysterectomy
Laparoscopic operative procedures have revolutionized gynecological surgery. These have several advantages: a smaller and more cosmetic incision, reduced blood loss and shorter postoperative stay, which cuts down on hospital…
- Trial name
- NCT01845532
- Testing
- TPI, EMLA cream
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Yonsei University
Myoma;Uterus, Blood Loss
Reducing Blood Loss During Myomectomy:Uterine Artery Ligation Vs Pericervical Tourniquet
The goal of this clinical trial is to compare two surgical techniques for reducing blood loss during transabdominal myomectomy in women with symptomatic uterine fibroids.
- Trial name
- NCT07526311
- Testing
- Bilateral Uterine Artery Ligation, Pericervical Mechanical Tourniquet Application
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Myoma;Uterus
Transverse vs Longitudinal Incision in Myomectomy
The Aim of the study is to compare between transverse and longitudinal uterine incision in abdominal myomectomy regarding intraoperative blood loss.
- Trial name
- NCT03009812
- Testing
- Longitudinal uterine incision, Transverse uterine incision
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Benign Uterine Tumor
The Clinical Trial About Treatment of Benign Uterus Myoma by Haifu Focused Ultrasound Tumor Therapeutic System
Uterine benign tumor including myoma is the most common female benign pelvic tumor. Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) has been considered to be a minimal invasive treatment.
- Trial name
- NCT05569200
- Testing
- Haifu Focused Ultrasound tumor therapeutic System
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Atypical, Myoma
Transcervical Myoma Biopsy Video
To describe the fertility-sparing management of an atypical uterine myoma. Step-by-step video explanation of transcervical biopsy using transabdominal ultrasound guidance, highlighting tips and tricks.
- Trial name
- TMBV (NCT04983719)
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Montpellier
Adenomyosis, Uterine Leiomyoma
The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms
The aim of this study is to assess the relationship between adenomyosis/myoma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
- Trial name
- NCT02495311
- Testing
- myomectomy or adenomyomectomy
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Uterine Myomas
PGL4001 Versus Placebo in Uterine Myomas
This trial will assess the efficacy and safety of PGL4001 with concomitant iron administration versus placebo with concomitant iron administration, over a 3-month period for the pre-operative treatment of pre-menopausal women…
- Trial name
- PEARLI (NCT00755755)
- Testing
- PGL4001 (ulipristal) and iron
- Where
- 38 sites in Czechia, Hungary and 4 more
- Volunteers
- 241 people
- Sponsor
- PregLem SA
Uterine Myoma, Surgery, Laparoscopic
Safety and Efficacy of Using a Novel Full Visual Access Platform System in Transvaginal Hysterectomy
The modified vNOTES hysterectomy was accomplished and validated for efficacy and safety using a multi-access vaginal confinement instrument with a fully visualised vaginal access platform.
- Trial name
- NCT06658145
- Testing
- Vnotes surgery using fully visualised surgical instruments, Vnotes surgery using traditional surgical instruments
- Where
- China
- Volunteers
- 94 people
- Sponsor
- China-Japan Friendship Hospital
Myomas, Ovary Cysts
The Efficacy and Safety Study of a New Cross-linked Hyaluronan Hydrogel in the Reduction of Postsurgical Peritoneal Adhesions
The purpose of this study was to determine whether the new crosslinked hyaluronan hydrogel was safe to use, and was effective for the prevention/reduction of adhesion formation following gynecological surgery
- Conditions
- Myomas, Ovary Cysts, Endometriotic Cysts, Adhesions
- Trial name
- BAP (NCT02166554)
- Testing
- Saline, Cross-linked Hyaluronan Hydrogel
- Where
- 7 sites in China
- Volunteers
- 216 people
- Sponsor
- BioRegen Biomedical (Changzhou) Co., Ltd
Patients With an Indication for Myomectomy or Polymyomectomy
Hyaluronic Acid for the Prevention of Endocavitary Synechiae After Myomectomy
PREVENDO is a prospective, multicenter, pilot, and randomized study in 2 parallel arms and single blind, evaluating the proportion of endometrial synechiae 6 weeks after surgery in patients undergoing abdominal myomectomy or…
- Trial name
- PREVENDO (NCT04702399)
- Testing
- GEL GROUP
- Volunteers
- 76 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris