Clinical trials: Myomectomy, open to volunteers
Myoma, Surgery
Impact of Uterine and Ovarian Vessel Occlusion on Blood Loss in High Burden Minimally Invasive Myomectomy.
This study hypothesizes that temporary bilateral uterine and utero-ovarian artery occlusion with laparoscopic clamps at time of minimally invasive myomectomy will lead to a decreased blood loss at time of myomectomy compared to…
- Trial name
- Myo-Bleed (NCT07182045)
- Testing
- Temporary clamping of uterine and ovarian vessels
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Infertility, In Vitro Fertilization (IVF)
The Impact of Myomectomy on IVF Outcomes: A Multicenter Randomized Controlled Trial
Uterine fibroids are the most common benign tumors of the female reproductive system and are frequently encountered in women of reproductive age.
- Conditions
- Infertility, In Vitro Fertilization (IVF), Uterine Myomas, Leiomyomas, or Fibromas
- Trial name
- MIO (NCT07578623)
- Testing
- Myomectomy
- Volunteers
- 792 people
- Sponsor
- Peking Union Medical College Hospital
Surgery
LapBox® Manual Containment System
This study to evaluate the leak integrity of the LapBox Manual Containment System for laparoscopic hysterectomy and myomectomy. The goal is to determine the integrity of this containment system in order to increase surgical…
- Trial name
- NCT07767968
- Testing
- LapBox Manual Containment System, Standard of Care Specimen Bag
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Wisconsin, Madison
Fibroid, Uterine Corpus Smooth Muscle Neoplasm
Evaluation of Ultrasound-guided Transuterine Vaginal Biopsy Technique in Uterine Fibromatous Disease
The goal of this diagnostic, prospective study is to evaluate an innovative, minimally invasive surgical technique for diagnosing uterine smooth muscle tumors by biopsy, in women aged 18 and more, and to evaluate complications…
- Trial name
- EFIBIA (NCT06576362)
- Testing
- Echoguided transuterine vaginal biopsy performed before myomectomy or hysterectomy
- Volunteers
- 250 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Postoperative Pain, Fibroid Uterus
QL Block in Laparoscopic Myomectomy
This study aims to determine the efficacy of a quadratus lumborum (QL) block in decreasing postoperative pain in patients undergoing myomectomy for uterine fibroids.
- Trial name
- NCT05979493
- Testing
- Bupivacain, Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Joseph Findley MD
Adenomyosis, Fibroid Uterus
Fertility Limiting Diseases of Pelvic Organs and Their Influence on Receptivity of Endometrial Cavity: Prospective Clinical Trial
In this project, we will characterize the effects of fertility limiting diseases of pelvic organs on the receptivity of the endometrium.
- Conditions
- Adenomyosis, Fibroid Uterus, Endometriosis
- Trial name
- REAdME (NCT06991595)
- Testing
- cytoreductive resection of adenomyosis, myomectomy, resection of endometriosis, hysteroscopy
- Where
- Czechia
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
LAZMAR Scoring , Hysteroscopic Myomectomy
"Evaluating The Applicability of LASMAR Scoring in Predicting Surgical Outcomes Of Hysteroscopic Myomectomy"
This study aims to evaluate the applicability of the LASMAR scoring system, derived from hysteroscopy, in predicting surgical outcomes in patients undergoing hysteroscopic myomectomy for submucous fibroids.
- Trial name
- NCT07578246
- Testing
- Hysteroscopic Myomectomy
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Laparoscopic Myomectomy
Temporary Uterine Tourniquet Application Versus Local Myometrial Epinephrine Injection During Laparoscopic Myomectomy
While both local vasoconstrictors and tourniquet application are recognized methods for blood loss control, there is a paucity of head-to-head randomized controlled trials directly comparing these two distinct approaches in…
- Trial name
- NCT07525687
- Testing
- Temporary Uterine Tourniquet Application, Local Myometrial Epinephrine Injection
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Minia University
to Determine Whether Patient Satisfaction With Postoperative Telehealth Follow-up is Non-inferior to In-person Clinic Visits
Outpatient Visits Versus Telehealth for Postoperative Care After Minimally Invasive Gynecologic Surgery
Telehealth, or telemedicine, utilizes technology to deliver clinical care remotely, either in real time or asynchronously, between clinician and patient.
- Trial name
- Telehealth RCT (NCT07420114)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Cystectomy, Myomectomy
Lidocaine for LESS Postoperative Shoulder Pain Alleviation
Objective: To evaluate the efficacy of subdiaphragmatic spray of 0.08% lidocaine in relieving postoperative acute pain and psychological status of patients undergoing single-port laparoscopic surgery for benign gynecological…
- Trial name
- NCT07537127
- Testing
- subdiaphragmatic lidocaine sprayed, standard ERAS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Myoma;Uterus, Blood Loss
Reducing Blood Loss During Myomectomy:Uterine Artery Ligation Vs Pericervical Tourniquet
The goal of this clinical trial is to compare two surgical techniques for reducing blood loss during transabdominal myomectomy in women with symptomatic uterine fibroids.
- Trial name
- NCT07526311
- Testing
- Bilateral Uterine Artery Ligation, Pericervical Mechanical Tourniquet Application
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Laparoscopic Myomectomy
Reducing Operative Blood Loss in Laparoscopic Myomectomy With Umbilico-uterine Trunk Clipping
the purpose of this study is to examine how Umbilico-uterine trunk occlusion reduces surgery-associated blood loss in Laparoscopic Myomectomy.
- Trial name
- NCT07200778
- Testing
- umbilico-uterine trunk occlusion, local epinephrine infiltration
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Minia University
Postoperative Pain
The Impact of Intraperitoneal Spray Combined With Intravenous Lidocaine on Postoperative Pain After Myomectomy
The purpose of this study is to determine whether laparoscopic spraying combined with intravenous injection of lidocaine can improve pain in patients undergoing laparoscopic myomectomy under general anesthesia.
- Trial name
- NCT07268495
- Testing
- Saline, intravenous +saline lidocaine, saline + intraperitoneal lidocaine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
Myoma;Uterus, Myomectomy; Surgical Blood Loss
Prevention of HEMOrhagic Risk in Upper MYOmeCTomy by Use of Misoprostol.
In France, uterine fibroids or leiomyomas are the most common benign tumour in women of childbearing age. In 30% of cases, fibroids are symptomatic (menorrhagia, anaemia, pain), in which case surgical management is indicated.
- Trial name
- HEMOMYOC (NCT06882824)
- Testing
- myomectomy with misoprostol
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Myoma
Prevention of Intra-uterine Adhesions Following Laparoscopic and Laparotomic Myomectomy
Clinical study on the prevention of intrauterine adhesions after laparoscopic or laparotomic myomectomy. Myomas are common in women of reproductive age and myomectomy can lead to intra-uterine adhesions, which can be detrimental…
- Trial name
- PALLM (NCT05683041)
- Testing
- Hyalobarrier
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Leiomyoma, Uterine
Clinical Research on the Application of Single-channel Uterine Fibroid Morcellation System in Laparoscopic Myomectomy
Research Purpose The purpose of this study is to explore whether the application of a single-channel uterine fibroid morcellation system compared to a multi-channel specimen retrieval bag during laparoscopic myomectomy can…
- Trial name
- NCT06442605
- Testing
- single-channel uterine fibroid morcellation system, Multi-channel specimen retrieval bag + conventional laparoscopic uterine fibroid morcellator
- Where
- China
- Volunteers
- 22 people
- Sponsor
- First People's Hospital of Hangzhou
Fallopian Tube Patency Tests, Fibroid/Myoma (Uterus/Cervix)
Assessment of Tubal Occlusion During Minimally Invasive Myomectomy
This study uses a procedure called chromopertubation to look at how fibroids and fibroid surgery affect the fallopian tubes. Specifically, this study will test if the fallopian tubes are occluded or patent (open) before and after…
- Conditions
- Fallopian Tube Patency Tests, Fibroid/Myoma (Uterus/Cervix), Myomectomy, Fallopian Tube Disease
- Trial name
- ATOM (NCT06988774)
- Testing
- chromopertubation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medstar Health Research Institute
Blood Loss, Surgical
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
The uterine fibroids are the most common benign tumors found in the female reproductive system. Uterine fibroids commonly cause heavy menstrual periods.
- Trial name
- NCT07721623
- Testing
- Carbetocin
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Alex Ekwueme Federal University Teaching Hospital
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Uterine Fibroids (Leiomyoma)
FATIMA Trial: EGCG and Vitamin D3 for Prevention of Fibroid Recurrence
The aim of this randomized controlled clinical trial is to evaluate the efficacy of green tea (EGCG) and vitamin D3 supplementation in preventing uterine fibroid recurrence following fibroid removal.
- Trial name
- FATIMA (NCT07647198)
- Testing
- Vitamin D and Green Tea
- Where
- United Arab Emirates
- Volunteers
- 240 people
- Sponsor
- Sheikh Shakhbout Medical City