Clinical trials: Myopathies
Temporomandibular Joint Disorders
Nocipoint Therapy Versus Standard Physical Therapy Using Electrical Stimulation in Treating Pain From TMJ Disorder
The purpose of this study is to measure the effect of nocipoint therapy on patients with temporomandibular joint disorders (TMD) and compare it with the effect of standard electrical stimulation therapy.
- Trial name
- NCT01676129
- Testing
- Nocipoint Therapy, Physical Therapy
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Temporomandibular Joint Dysfunction, Craniocervical Dysfunction
Craniocervical Dysfunction Index in Patients With Temporomandibular Joint Dysfunction
The aims of this study were to perform cultural adaptation of the Craniocervical Dysfunction Index in patients with Temporomandibular Joint Dysfunction, reliability and validity of the index Turkish speaking adults.
- Conditions
- Temporomandibular Joint Dysfunction, Craniocervical Dysfunction, Reliability, Validity
- Trial name
- NCT06655753
- Testing
- Reliability and Validity
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Alanya Alaaddin Keykubat University
Duchenne Muscular Dystrophy
Telerehabilitation-based Motor Imagery Training in Children With Duchenne Muscular Dystrophy
When the field of neurorehabilitation is examined, most of the current physiotherapy and rehabilitation approaches are based on real movements to stimulate damaged motor neural connections through neuroplasticity.
- Trial name
- NCT06109103
- Testing
- telerehabilitation-based motor imagery training, telerehabilitation-based physiotheraphy training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Long COVID, Chronic Fatigue Syndrome
tVNS in Long COVID-19
A prior open label study has shown that transcutaneous vagus nerve stimulation [tVNS] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill…
- Trial name
- NCT06585254
- Testing
- Transcutaneous vagus nerve stimulator
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post-Polio Syndrome
Post-Poliosyndrome Treated With Intravenous Immunoglobulin (IvIg)
Inflammatory cytokines in the cerebrospinal fluid may contribute to the new muscle weakness, fatigue and pain experienced by patients with post-polio syndrome. Intravenousimmunoglobulin (IvIg) reduces this inflammation.
- Trial name
- NCT00231439
- Testing
- IvIg
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Juvenile Dermatomyositis, Rheumatic Diseases
Comparison Of The Effects Of Two Different Exercise Training Based On Internal And External Focus In Children and Adolescents With Rheumatic Diseases
The study aims to compare the effects of two different exercise programs, based on distinct focus strategies, on physical fitness and fatigue in children and adolescents with rheumatic diseases.
- Conditions
- Juvenile Dermatomyositis, Rheumatic Diseases, Juvenile Idiopathic Arthritis (JIA), Familial Mediterranean Fever (FMF)
- Trial name
- NCT07138157
- Testing
- External Focus Exercises, Internal Focus Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University - Cerrahpasa
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Trigger Point Pain, Myofascial, Chronic Shoulder Pain
Effects of Dry Needling When Applied to the Infraspinatus Muscle in People With Chronic Shoulder Pain
Up to 77% of patients with chronic shoulder pain have a trigger point (TrP) in the infraspinatus muscle. These TrPs can lead to pain, limitation of activities and reduced quality of life.
- Trial name
- NCT04316793
- Testing
- Dry needling
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Université de Sherbrooke
Fibromyalgia
Efficacy of Acupuncture in the Treatment of Fibromyalgia
Fibromyalgia (FM), one of the most common rheumatic conditions, is a condition of unknown etiology characterized by widespread muscle pain and stiffness.
- Trial name
- NCT00010764
- Testing
- Acupuncture
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)
The goal of this clinical trial is to evaluate the long-term safety and tolerability of zagociguat in patients with MELAS who completed study medication treatment in the lead-in study TIS6463-203.
- Trial name
- NCT06961344
- Testing
- zagociguat 15mg
- Where
- 16 sites in United States, Australia and 3 more
- Volunteers
- 37 people
- Sponsor
- Tisento Therapeutics
Lateral Epicondylitis, Central Sensitization
Central Sensitization and Ultrasound in Lateral Epicondylitis
Lateral epicondylitis (LE) is a common musculoskeletal disorder characterized by pain and tenderness over the lateral elbow and may become chronic despite conservative treatment.
- Trial name
- NCT07827898
- Testing
- Pressure pain threshold, Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Fibromyalgia
Effectiveness of an IVR-based Therapeutic Exercise Program With Altered Visual Feedback in Fibromyalgia Patients
The primary aim of this randomized controlled trial is to determine the efficacy of a 6-week immersive virtual reality (IVR)-based therapeutic exercise intervention, which manipulates visual proprioceptive input during exercise…
- Trial name
- IVR-F (NCT06948500)
- Testing
- Immersive Virtual Reality, Physical Activity
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Cardenal Herrera University
Dystrophia Myotonica 1
Methylphenidate in Myotonic Dystrophy Type 1
The purpose of this study is to determine whether methylphenidate is effective in the treatment of excessive daytime sleepiness due to myotonic dystrophy type 1 (DM1).
- Trial name
- NCT01421992
- Testing
- Methylphenidate
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Laval University
Systemic Sclerosis, Fibromyalgia
Effects of Fibromyalgia Syndrome in Patients With Systemic Sclerosis
Systemic sclerosis [SSc]; is a multisystem disease characterized by immune activation, microvascular disease and fibroblast dysfunction, which is thought to occur as a result of complex and not fully understood interaction…
- Trial name
- NCT04411498
- Testing
- Fibromyalgia diagnosis in patients with SSc
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Spasticity as Sequela of Stroke
EXOPULSE Mollii Suit, Motor Function & Stroke (EXOSTROKE)
Spasticity is a common and debilitating complication in neurological conditions such as multiple sclerosis, cerebral palsy, and stroke.
- Trial name
- EXOSTROKE (NCT06702163)
- Testing
- EXOPULSE MOLLII SUIT (active)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Post-Viral Fatigue Syndrome
Rehabilitation Robot in Patients With Post-Coronavirus Disease (COVID-19) Fatigue Syndrome
The aim of the study is to compare the effectiveness of two models of rehabilitation: traditional neurological rehabilitation, and neurological rehabilitation combined with a rehabilitation robot (Luna by EGZOTech).
- Trial name
- NCT05130736
- Testing
- Robot rehabilitation
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
Dactinomycin Adverse Reaction, Bone and Joint Infection
Pharmacokinetics and Toxicodynamics of Daptomycin in Bone and Joint Infections
the aim of this study is to investigate the relationship between exposure to daptomycin and the occurrence of muscle toxicity or eosinophilic pneumonia in patients treated with daptomycin for bone and joint infection
- Trial name
- PKTOXDAP (NCT04933344)
- Testing
- patients having had BJI or PJI treated with daptomycin
- Where
- France
- Volunteers
- 1,130 people
- Sponsor
- Hospices Civils de Lyon
Duchenne Muscular Dystrophy
A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMN 351 in Participants With Duchenne Muscular Dystrophy
The purpose of this study is to test the safety and tolerability of BMN 351 in participants with Duchenne Muscular Dystrophy (DMD) with a genetic mutation amenable to exon 51 skipping.
- Trial name
- NCT06280209
- Testing
- BMN 351
- Where
- 7 sites in Italy, Netherlands and 3 more
- Volunteers
- 18 people
- Sponsor
- BioMarin Pharmaceutical
Myofascial Pain Syndromes
Comparison of Efficacy of Dry Needling and Kinesio-taping
The aim of the current study was to investigate the effects of KT and DN combined with exercise on pain, range of motion (ROM), and upper extremity function in patients with common shoulder disorders.
- Trial name
- NCT04504409
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Istanbul University - Cerrahpasa
Diaphragmatic Dysfunction, Muscle Weakness
Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex
The effect of neuromuscular blocking agents (NMBA, e.g. rocuronium) on respiratory muscle activity is well known. However, since the availability of sugammadex, to our knowledge, no study has been conducted to evaluate the effect…
- Conditions
- Diaphragmatic Dysfunction, Muscle Weakness, Muscle Fatigue
- Trial name
- SUDIA (NCT01962298)
- Testing
- sugammadex 2mg/kg, neostigmine, sugammadex 4mg/kg
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- University Hospital, Antwerp
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