Clinical trials: Myopathies
Fibromyalgia, Insomnia
Sleep and Pain Interventions in Women With Fibromyalgia
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia.
- Conditions
- Fibromyalgia, Insomnia, Chronic Widespread Pain
- Trial name
- SPIN-II (NCT03744156)
- Testing
- Cognitive Behavioral Treatment-Insomnia, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Missouri-Columbia
Medial Tibial Stress Syndrome
Effect of Shortwave Diathermy and Therapeutic Ultrasound on Medial Tibial Stress Syndrome Among Military Cadets
Medial tibial stress syndrome (MTSS) also known as shin splints or tibial periostitis is a common injury in athletes and soldiers/cadets with incidences ranging between 4% and 35% in these populations .
- Trial name
- NCT04292795
- Testing
- Therapeutic Ultrasound, Short wave diathermy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Shifa Clinical Research Center
Healthy Volunteers, Muscle Fatigue
Effects of Recoverben® on Recovery After Exhaustive Exercise
The aim of the study is to investigate a pre and post workout supplementation (15 days) with Recoverben® , a Aloysia citriodora extract on recovery after exhaustive exercise.
- Conditions
- Healthy Volunteers, Muscle Fatigue, Muscle Soreness
- Trial name
- NCT02923102
- Testing
- Aloysia citriodora extract, Maltodextrin
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vital Solutions GmbH
Pain, Persistent Pain
Is Low-load Resistance Training With Blood Flow Restriction More Effective Than Traditional Rehabilitation of Military Personnel With Lower Limb Injuries
Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes.
- Conditions
- Pain, Persistent Pain, Musculoskeletal Pain
- Trial name
- LIMITLESS (NCT06621953)
- Testing
- BFR, control group
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Myofascial Pain Dysfunction Syndrome, Myofascial Pelvic Pain Syndrome
Precise AI-Controlled Radiofrequency Versus Biofeedback-Electrical Stimulation in Women With Myofascial Pelvic Pain Syndrome: A Comparative Study
Study Summary: Comparison of Two Treatments for Female Myofascial Pelvic Pain Syndrome The goal of this study is to compare two treatment methods-precise AI-controlled radiofrequency therapy versus biofeedback combined with…
- Trial name
- NCT07791277
- Testing
- Intervention 1：Precision AI Temperature-Controlled Radiofrequency, Intervention 2:Biofeedback Combined with Electrical Stimulation
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jiangxi Women and Children's Medical Center
Musculoskeletal Pain
Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment
The purpose of this study is to evaluate the safety and efficacy of an association with one anti-inflammatory and one muscle relaxant plus caffeine compared to one anti-inflammatory plus caffeine in the treatment of osteomuscular…
- Trial name
- NCT02862977
- Testing
- ketoprofen and cyclobenzaprine association with caffeine, Cyclobenzaprine with caffeine
- Where
- 6 sites in Brazil
- Volunteers
- 414 people
- Sponsor
- EMS
Motor Neuron Disease
A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.
The COMMEND Study will assess the safety and effectiveness of FLX-787 in men and women with Motor Neuron Disease [including Amyotrophic Lateral Sclerosis (ALS), Primary Lateral Sclerosis (PLS) or Progressive Muscular Atrophy…
- Trial name
- NCT03196375
- Testing
- FLX-787-ODT (orally disintegrating tablet)
- Where
- 35 sites in United States
- Volunteers
- 54 people
- Sponsor
- Flex Pharma, Inc.
Paraparesis, Gait Disorders, Neurologic
Effect of Electromagnetic Field Therapy on Balance and Gait in Paraparetic Patients
This study will investigate whether adding electromagnetic field therapy (EMT) to a standard physical therapy program is more effective than physical therapy alone for improving balance and walking ability in paraparetic…
- Conditions
- Paraparesis, Gait Disorders, Neurologic, Postural Balance Disorders
- Trial name
- EMT-BG (NCT07196956)
- Testing
- Low-Frequency Electromagnetic Field Therapy (0.5 Hz)
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- MTI University
Musculoskeletal Pain
Can a Digital Tooll Facilitate Shared Decision-making and Increase Self-efficacy in Vocational Rehabilitation?
The study investigates both the effects and the experienced value of the mobile application, MIRA, which is a combination of an electronic diary, a dialogue tool and a decision support tool.
- Trial name
- NCT04695002
- Testing
- MIRA, Control
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Region MidtJylland Denmark
Stroke, Brain Injuries
The Efficacy of Dynamic Hand Splint Treatment in Spastic Hemiparetic Patients
The purpose of this randomized controlled trial was designed to study the efficacy of dynamic hand splinting on spastic hemiparetic patients due to stroke or traumatic brain injury.
- Trial name
- NCT04441437
- Testing
- Task-oriented training with a dynamic hand splint, Task-oriented training without a dynamic hand splint
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Fibromyalgia
Improving Quality of Life of Fibromyalgia Patients
Comparison of two treatments of fibromyalgia; the QOL score should improve rather and, twelve months after the end of the program, remain higher in "Plurifocal educational group" than in control group
- Trial name
- Aquavip (NCT00715195)
- Testing
- Plurifocal educational program
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fibromyalgia (FM)
Cannabis Extract in Fibromyalgia Syndrome - the SUNRISE Study
The aim of this observational study is to evaluate the effects of cannabis extract Avextra 10/10 solution on pain, fatigue, sleep, and quality of life among patients affected by fibromyalgia (FM) syndrome.
- Trial name
- SUNRISE (NCT06747039)
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Mitochondrial Diseases, Maternally Inherited Diabetes and Deafness (MIDD)
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
The KHENERFIN study aims to determine whether the study medicine, sonlicromanol, is able to reduce symptoms of fatigue and the impact of fatigue on daily life, and whether sonlicromanol is able to improve physical abilities of…
- Conditions
- Mitochondrial Diseases, Maternally Inherited Diabetes and Deafness (MIDD), Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS), Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
- Trial name
- KH176-301 (NCT06451757)
- Testing
- Sonlicromanol
- Where
- 10 sites in United States, Denmark and 5 more
- Volunteers
- 220 people
- Sponsor
- Khondrion BV
Elbow Tendinopathy
The Analysis of Efficacy Factors for Autologous Platelet-Rich Plasma Therapy in the Treatment of Elbow Tendinopathy
To identify key factors influencing the effectiveness of platelet-rich plasma (PRP) therapy in treating elbow tendinopathy, a common degenerative condition.
- Trial name
- NCT06815042
- Testing
- Autologous Platelet-Rich Plasma (PRP) Injection
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- CHA University
Hamstring Tightness, Myofascial Pain
The Effects of Soft Tissue Therapy and Exercise on Hamstring Tightness
The purpose of this study is to investigate the effects of myofascial decompression (cupping) and neurodynamic sliding technique for the hamstring on Division I Track and Field athletes who complain of hamstring tightness.
- Conditions
- Hamstring Tightness, Myofascial Pain, Musculoskeletal Pain
- Trial name
- NCT03651141
- Testing
- Neurodynamic Sliding, Myofascial Decompression, Diathermy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Temporomandibular Disorders, Rheumatoid Arthritis
Biomarkers Associated With Temporomandibular Disorders in Patients With Rheumatoid Arthritis
The goal of this observational study is to determinate temeporomandibular disorders (TMDs) and levels of biomarkers in 30 rheumatoid arthritis patients and 30 healthy controls.
- Trial name
- NCT06488937
- Where
- Croatia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Lateral Elbow Pain, Lateral Epicondylitis
Illness Perception and Treatment Expectations in Lateral Elbow Pain
This cross-sectional, correlational study aims to determine the predictors of illness perception and treatment expectations in adults with chronic lateral elbow pain.
- Conditions
- Lateral Elbow Pain, Lateral Epicondylitis, Tennis Elbow, Chronic Musculoskeletal Pain
- Trial name
- LEP-IPTE (NCT07722845)
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Acibadem University
Fibromyalgia, Irritable Bowel Syndrome
Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders
Objectives : To investigate the analgesic effects of repeated sessions of unilateral rTMS in patients with chronic pain syndrome due to fibromyalgia, IBS or burning mouth syndrome. Primary outcome will be numerical pain scores.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Burning Mouth Syndrome
- Trial name
- NCT00374673
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital Ambroise Paré Paris
Contracture, Spasticity, Muscle
Effect of Cryoneurolysis on Pain in Patients With Hand Contracture.
Contracture which is defined as a limitation of the maximum passive range of motion due to changes in periarticular soft tissue can contributes to severe pain and increased disabilities.
- Trial name
- NCT06051656
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Vancouver Island Health Authority
Myofacial Pain Syndromes
The Efficacy of Low-level Laser on Cervical Myofascial Pain Syndrome
Objective: To compare the effectiveness of application of low-level laser therapy (LLLT) to trigger points and traditional acupoints for patients with cervical myofascial pain syndrome (MPS).
- Trial name
- NCT01516502
- Testing
- low-level laser therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
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