Clinical trials: Myopathies
Tendinopathy, Adrenal Insufficiency
Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to Corticosteroids Intrabursal Injection
The purpose of this study is to compare the efficacy and effects on the hypothalamus-pituitary-adrenal axis of a single intrabursal injection of two different types of corticosteroids (methylprednisolone and triamcinolone) in…
- Trial name
- TPESP2011-12 (NCT01652495)
- Testing
- methylprednisolone acetate, Triamcinolone Acetonide
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lateral Epicondylitis (Tennis Elbow)
Blood Flow Restriction Training Versus Mulligan Technique in Treatment of Lateral Epicondylitis
The purpose of this study is to evaluate the effectiveness of blood flow restriction training (BFRT) verses Mulligan's technique in improving pain, grip strength, and functional outcomes in patients with lateral epicondylitis…
- Trial name
- NCT07236554
- Testing
- blood flow restriction, Mulligan's with mobilization, Exercise
- Where
- Egypt
- Volunteers
- 177 people
- Sponsor
- Cairo University
Temporomandibular Joint Dysfunction Syndrome
Multidisciplinary Therapy in the Temporomandibular Joint Dysfunction in Patients With Fibromyalgia Syndrome
The purpose of this study is to determine the efficacy of a multidisciplinary therapy with physical, manual and deontology therapies in the treatment of temporomandibular joint dysfunction in patients with fibromyalgia syndrome.
- Trial name
- NCT01825629
- Testing
- Multidisciplinary therapy
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Universidad de Almeria
Long COVID, Chronic Fatigue Syndrome
Vagus Nerve Stimulation as Treatment for Long Covid
Many patients do not recover following Covid infection. The resulting illness is called Long Covid. Because there is no agreed upon treatment for this ailment, the research team has decided to do an open label pilot study using…
- Trial name
- NCT05608629
- Testing
- Transcutaneous Non-Invasive Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Myofascial Pain Syndrome (MPS), Masticatory Muscle Pain
EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles
This randomized controlled clinical trial aims to evaluate the individual and combined effects of occlusal splint therapy and botulinum toxin type A (BTX-A) injections into the masseter muscle on the activity of head and neck…
- Trial name
- NCT07082972
- Testing
- Botulinum toxin injection, Occlusal splint, Botulinum toxin + Occlusal splint combined
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01706172
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 Sterile water /0.2% lidocaine
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chisel Peak Medical Clinic
Lateral Epicondylitis
Clinical and Ultrasonographic Results of Intratissue Percutaneous Electrolysis in Lateral Epicondylitis
Lateral epicondylitis (LE) is the most common cause of lateral elbow pain. Intratissue percutaneous electrolysis (EPI technique) is a novel minimally invasive approach which consists in the application of a galvanic current…
- Trial name
- NCT02085928
- Testing
- Intratissue percutaneous electrolysis, associated with eccentric exercise and stretching
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- CEU San Pablo University
Idiopathic Inflammatory Myopathy
A Case-control Study to Assess Risk of Coronary Heart Disease in Idiopathic Inflammatory Myopathy
This study will be co-ordinated by Dr Hector Chinoy, Dr Robert G Cooper (Salford Royal NHS Foundation Trust / The University of Manchester) and Dr Ian N Bruce (Central Manchester University Hospitals NHS Foundation Trust/ The…
- Trial name
- NCT00971828
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northern Care Alliance NHS Foundation Trust
Fibromyalgia
The Effects of Energy Healing in Fibromyalgia
This study aims to study the clinical effects of Energy Healing using fMRI and determine its application to Fibromyalgia patients.
- Trial name
- NCT06552728
- Testing
- Energy Healing
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Danon Disease
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
This is a single arm Phase 2 trial to evaluate the efficacy and safety of RP-A501, a recombinant adeno-associated virus serotype 9 (rAAV9) vector containing the human lysosome-associated membrane protein 2 isoform B (LAMP2B)…
- Trial name
- NCT06092034
- Testing
- RP-A501
- Where
- 6 sites in United States, Germany and 2 more
- Volunteers
- 18 people
- Sponsor
- Rocket Pharmaceuticals Inc.
Fibromyalgia
The Effect of Milnacipran in Patients With Fibromyalgia
Use of the drug Milnacipran will reduce ventricular lactate levels and processing time for completing complex tasks relative to placebo.
- Trial name
- NCT01108731
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Beth Israel Medical Center
Fibromyalgia, Postural Lordosis
Trunk Position Sense, Postural Stability and Spinal Posture in Fibromyalgia
This study aims to investigate trunk position sense, postural stability and spine posture in fibromyalgia patients and healthy women.
- Conditions
- Fibromyalgia, Postural Lordosis, Postural Kyphosis, Proprioception
- Trial name
- NCT03757702
- Testing
- Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Muscle Weakness
CAPABLE for Frail Dually Eligible Older Adults
The Johns Hopkins School of Nursing offers this research study which aims to learn more about whether services that help with medications, muscle strengthening, pain management and changes to houses can help improve older adults'…
- Trial name
- CAPABLE500 (NCT01743495)
- Testing
- 10 home-based functional services sessions over 4 months.
- Where
- United States
- Volunteers
- 281 people
- Sponsor
- Johns Hopkins University
Stroke
Immediate Effects of Open and Closed Kinetic Chain Exercises on Upper Extremity in Stroke Patients.
Stroke is a sudden disruption of blood flow to the brain, resulting in physical and mental disabilities. It's a global health issue affecting millions each year, often leading to paralysis, altered muscle tone, and loss of motor…
- Trial name
- NCT06272175
- Testing
- Open Kinetic Chain Activity, Closed Kinetic Chain Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istinye University
Myotonia Congenita, Paramyotonia Congenita
Study of Ranolazine in Myotonia Congenita, Paramyotonia Congenita and Myotonic Dystrophy Type 1
The purpose of this study is to gather preliminary data to determine if ranolazine is a safe and effective treatment for the symptoms of myotonia congenital, paramyotonia congenita, and myotonic dystrophy type 1.
- Conditions
- Myotonia Congenita, Paramyotonia Congenita, Myotonic Dystrophy 1
- Trial name
- NCT02251457
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Ohio State University
Neck Pain, Range of Motion
Comparative Effect of Neck Isometrics and Deep Cervical Flexion Exercises on Neck Pain Among Breastfeeding Females.
Neck pain is a common complaint among breastfeeding females, potentially attributed to sustained postures and muscle imbalance. Breastfeeding females experiencing neck pain, aged between 18-40 years, will be recruited through…
- Conditions
- Neck Pain, Range of Motion, Muscle Weakness, Breastfeeding
- Trial name
- NCT06877728
- Testing
- Neck isometric exercises: 3 times weekly for 6 consecutive weeks (18 sessions)
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Tendinopathy
Identification and Treatment of Early Tendinopathy in Elite Athletes
Tendon injuries represent a significant problem in elite athletes. The understanding of the pathophysiology of tendinopathy is very sparse, and especially the early events in tendinopathy are unknown.
- Trial name
- NCT03642392
- Testing
- Identification and treatment of early tendinopathy
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Spasticity, Multiple Sclerosis
Efficacy Study of Arbaclofen to Treat Spasticity in Multiple Sclerosis
This is a multicenter, randomized (1:1:1), double-blind, active and placebo controlled, parallel group study to evaluate safety, tolerability and efficacy of oral arbaclofen in MS patients with spasticity.
- Trial name
- NCT01743651
- Testing
- arbaclofen, baclofen
- Where
- 48 sites in United States, Russia and 1 more
- Volunteers
- 353 people
- Sponsor
- RVL Pharmaceuticals, Inc.
Biceps Tendon Disorder, Tendinosis
Restoring the Anatomic Tension Relationship of the Long Head of the Biceps During Tenodesis
The goal of this clinical trial is to determine the clinical impact of restoring the anatomic-tension relationship of the long head of the biceps (LHB) when performing a biceps tenotomy and tenodesis.
- Conditions
- Biceps Tendon Disorder, Tendinosis, Rotator Cuff Injuries
- Trial name
- NCT06571695
- Testing
- Anatomic Long Head of Biceps Tensioning Technique, Traditional Long Head of Biceps Tensioning Technique
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Loyola University
Covid-19, Critical Illness
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Introduction: Survivors of acute respiratory failure develop persistent muscle weakness and deficits in cardiopulmonary endurance combining to limit physical functioning.
- Conditions
- Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
- Trial name
- OPTIMAL (NCT04412330)
- Testing
- ICU Recovery + Physical Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Kentucky
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