Clinical trials: Myopathies
Cirrhosis, Muscle Cramp
Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles Trial
This clinical trial is evaluating the feasibility of using a non-pharmaceutical treatment to improve the symptoms and severity of muscle cramps in patients with cirrhosis.
- Conditions
- Cirrhosis, Muscle Cramp, Ascites
- Trial name
- NCT04650295
- Testing
- Household Remedy, Tap water
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Michigan
Temporomandibular Disorders (TMD), Acute Apical Periodontitis of Pulpal Origin
The Role of Root Canal Treatment in Alleviating Endodontic Pain-Induced Asymmetry and Restoring Muscle Balance
The study hypothesizes that masticatory laterality caused by acute apical periodontitis pain result in muscle asymmetry. Furthermore, it posits that successful root canal treatment, by restoring normal bilateral chewing function…
- Trial name
- NCT06853028
- Testing
- ultrasound measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Cukurova University
Epicondylitis, Lateral
Epicondylar Muscle Activation in Tennis Players
Epicondylitis is one of the most common pathologies in tennis players. The search for an effective treatment is necessary for the relief of symptoms and the return to sports practice.
- Trial name
- NCT06160011
- Testing
- Electrical dry needling + Conventional physiotherapy, Dry needling + Conventional physiotherapy, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Covid19, Anosmia
Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)
The main aim of this study is to determine the effects of short-term treatment with hesperidin on COVID-19 symptoms in comparison with a placebo.
- Conditions
- Covid19, Anosmia, Fever, Cough
- Trial name
- Hesperidin (NCT04715932)
- Testing
- Hesperidin
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Montreal Heart Institute
Muscular Dystrophies, Scapular Dyskinesis
Evaluation of a Textile Scapula Orthosis
Shoulder instability due to muscle weakness is a common problem in disorders of the upper extremities. During arm motion, the scapula acts as a dynamic base for the humeral head.
- Conditions
- Muscular Dystrophies, Scapular Dyskinesis, Muscular Dystrophy, Facioscapulohumeral, Muscle Weakness
- Trial name
- ScapOrthosis (NCT04154098)
- Testing
- Scapula orthosis assistance, Manual scapula assistance, No assistance
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 8 people
- Sponsor
- Swiss Federal Institute of Technology
Muscular Dystrophy, Duchenne
Study of Fordadistrogene Movaparvovec in Early Stage Duchenne Muscular Dystrophy
The study will evaluate the safety and dystrophin expression following gene therapy in boys with Duchenne Muscular Dystrophy (DMD). It is a single-arm, non-randomized, open-label study
- Trial name
- NCT05429372
- Testing
- PF-06939926
- Where
- 13 sites in United States, Australia
- Volunteers
- 10 people
- Sponsor
- Pfizer
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina
Fibromyalgia, Primary, Fibromyalgia, Secondary
A Study for Adult Patients With Fibromyalgia
The main purpose of this study is to determine if 30 milligrams (mg) of duloxetine is effective in the treatment of fibromyalgia compared to placebo.
- Trial name
- HMGG (NCT00965081)
- Testing
- Duloxetine
- Where
- 4 sites in Mexico
- Volunteers
- 308 people
- Sponsor
- Eli Lilly and Company
Rhabdomyolysis
Effect of Battlefield Acupuncture on Pain Control During Inpatient Treatment of Exertional Rhabdomyolysis
Patients admitted with exertional rhabdomyolysis will be offered treatment with battlefield acupuncture for pain management and compared with patient's pain levels and pain medication requirements with those patients who declined…
- Trial name
- NCT07528300
- Testing
- Battlefield Acupuncture
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tripler Army Medical Center
Atopic Dermatitis, Psoriasis
Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases
Chronic inflammatory skin diseases constitute a heterogeneous group of pathologies. They affect the skin but also other organs (joints, lungs, muscles, etc.). Their prognosis and response to treatments is extremely variable.
- Conditions
- Atopic Dermatitis, Psoriasis, Hidradenitis Suppurativa, Lichen Planus
- Trial name
- ImmuneSkinBank (NCT06599411)
- Testing
- Sampling
- Where
- France
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Limb Girdle Muscular Dystrophy
Cell Therapy in Limb Girdle Muscular Dystrophy
The purpose of this study was to study the effect of stem cell therapy on Limb Girdle Muscular Dystrophy patients.
- Trial name
- NCT02245711
- Testing
- Stem Cell
- Where
- India
- Sponsor
- Neurogen Brain and Spine Institute
Pain, Fibromyalgia
Real-time Pain Monitoring in Fibromyalgia Patients
This study aims to examine whether the pain of fibromyalgia patients can be reduced with utilization of real-time pain monitoring system (PAAS).
- Trial name
- NCT03571009
- Testing
- utilization of PAAS
- Volunteers
- 25 people
- Sponsor
- Ji Hyeon Ju
Pancreatic Neoplasms, Cachexia
Strength Training on Pancreatic Cancer
The purpose of this study is to determine whether prednisone, methotrexate, and cyclophosphamide are effective in the treatment of rapidly progressive hearing loss in both ears due to autoimmune inner ear disease (AIED).
- Conditions
- Pancreatic Neoplasms, Cachexia, Myopathy
- Trial name
- STOPC (NCT01395563)
- Testing
- strength training
- Where
- 3 sites in Germany
- Sponsor
- German Cancer Research Center
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Temporomandibular Joint Dysfunction
Effect of Intra-articular Injection on Temporomandibular Joint Dysfunction
The goal of this clinical trial is to study about the clinical effect of Intra-articular Injection on Temporomandibular Joint Dysfunction The main question it aims to answer is: Can Intra-articular Injection help improve the…
- Trial name
- NCT06213675
- Testing
- Routine rehabilitation treatment, Intra-articular Injection
- Where
- China
- Sponsor
- Zeng Changhao
Polymyositis, Dermatomyositis
A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care Treatments
The purpose of this study is to evaluate the efficacy of ustekinumab in participants with active polymyositis (PM)/dermatomyositis (DM) despite receiving 1 or more standard-of-care treatments (for example, glucocorticoids and/or…
- Trial name
- NCT03981744
- Testing
- Ustekinumab 6 mg/kg, Ustekinumab 90 mg
- Where
- 32 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Janssen Pharmaceutical K.K.
Fibromyalgia
Newer Antidepressants in Combination With Pregabalin for Fibromyalgia Syndrome
Background: The investigator hypothesized that the combined use of pregabalin and paroxetine would be associated with comparable Somatic Symptoms Scale-8 (SSS-8) and higher tolerability than amitriptyline or venlafaxine.
- Trial name
- NCT02451475
- Testing
- Amitriptyline, Venlafaxine, Paroxetine
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Subacute Stroke, Upper Limb
Additional Effects of Kinesio-Taping Along with Conservative Physical Therapy on Upper Limb Function, Range of Motion and Spasticity in the Patients with Subacute Stroke
A randomized control trial will be done on diagnosed stroke patients of subacute stage in Fauji Foundation Hospital Rawalpindi and leading edge physical therapy and rehabilitation clinic.The purpose of the study is to determine…
- Conditions
- Subacute Stroke, Upper Limb, Range of Motion, Spasticity
- Trial name
- NCT06674057
- Testing
- KinesioTaping, Control
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Pseudo Angina, Myofascial Pain Syndromes
Treatment of Pectoralis Trigger Points in Patients With Pseudo Angina
Pseudo-angina is a musculoskeletal condition characterized by chest pain that resembles angina but occurs due to non-cardiac causes, particularly myofascial trigger points in the chest wall muscles.
- Conditions
- Pseudo Angina, Myofascial Pain Syndromes, Pectoralis Muscles, Musculoskeletal Chest Pain
- Trial name
- GT-LIC (NCT07728357)
- Testing
- Graston Technique, Local Ischemic Compression
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Faisalabad
Pigmented Villonodular Synovitis, Diffuse-type Giant Cell Tumor
Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor
Nilotinib is a drug that is used to treat a form of a blood cancer called leukemia. Nilotinib works by blocking the action of a protein that might be important for the growth of pigmented villonodular synovitis (PVNS).
- Conditions
- Pigmented Villonodular Synovitis, Diffuse-type Giant Cell Tumor, Tenosynovial Giant Cell Tumor
- Trial name
- NCT01207492
- Testing
- nilotinib
- Where
- 7 sites in United States
- Volunteers
- 17 people
- Sponsor
- Andrew J. Wagner, MD, PhD
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