Clinical trials: Myopathies
Temporomandibular Joint Disorders
Effects of Bowen's Therapy and Post Isometric Relaxation Techniques in Patients of Temporomandibular Joint Disorder
the aim of this study to compare effects of Bowen's therapy and post isometric relaxation techniques on pain, range of motions and function in patients with TMJ disorder.
- Trial name
- NCT05392049
- Testing
- Bowen's therapy, Post isometric relaxation
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Temporomandibular Disorders, Headache
The BETY-Biopsychosocial Questionnaire (BETY-BQ) in Individuals With Temporomandibular Dysfunction-Related Headache
This study investigates the validity and reliability of the BETY- Biopsychosocial Questionnaire (BETY-BQ) as a biopsychosocial assessment tool in individuals with temporomandibular dysfunction-related headaches.
- Trial name
- NCT05902026
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hasan Kalyoncu University
Liver Disease Chronic, Muscle Weakness
Inspiratory Muscle Training Post-Liver Transplant
Individuals with chronic liver disease develop significant muscle wasting that remains post-liver transplant. The transplant surgery additionally challenges respiratory mechanics.
- Conditions
- Liver Disease Chronic, Muscle Weakness, Respiratory Insufficiency
- Trial name
- NCT03130608
- Testing
- Inspiratory Muscle Training
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Miami
Obstructive Sleep Apnea Syndrome, Temporomandibular Disorders
Side Effects of Mandibular Advancement Devices
Sleep-related breathing disorders (SBAS) are one of the most common causes of non-restorative sleep. Sleep therapy options include positive pressure ventilation with continuous positive airway pressure (CPAP) masks, mandibular…
- Trial name
- NCT04050514
- Testing
- H-MAD with a hinge system according to Herbst
- Where
- 9 sites in Germany
- Volunteers
- 65 people
- Sponsor
- University Medicine Greifswald
Tinnitus, Subjective, Temporomandibular Disorder
Evaluation of the Effect of Muscle Activity on Subjective Tinnitus in Temporomandibular Disorders
Treatment of Temporomandibular Joint Disorder can help reduce subjective tinnitus levels. This treatment changes the electrical activity of the patient's chewing muscles.
- Trial name
- NCT05830604
- Testing
- Occlusal Splint Treatment- Non Invasive treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kutahya Health Sciences University
Rumination, Fibromyalgia
Repetitive Thinking in Fibromyalgia
Some fibromyalgia patients may use inappropriate emotional regulation strategies to respond to pain. Rumination could be one of this inefficient regulation strategies.
- Conditions
- Rumination, Fibromyalgia, Chronic Pain, Repetitive Negative Thinking
- Trial name
- PRFM-3 (NCT03964285)
- Testing
- rumination induction, distraction induction
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Becker Muscular Dystrophy
A Study to Assess Vamorolone in Becker Muscular Dystrophy (BMD)
This Phase II pilot study is a randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, PK, PD, and exploratory clinical efficacy of vamorolone 500mg (250mg for body weight <50 kg) daily…
- Trial name
- NCT05166109
- Testing
- Vamorolone
- Where
- 2 sites in United States, Italy
- Volunteers
- 46 people
- Sponsor
- ReveraGen BioPharma, Inc.
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin Combined With Toludesvenlafaxine in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Duloxetine, Pain
- Trial name
- NCT07208357
- Testing
- Pregabalin, Pregabalin with toludesvenlafaxine
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Beijing Tiantan Hospital
Inflammatory Myopathy, Idiopathic, Dermatomyositis
Add-on Intravenous Immunoglobulins in Early Myositis
In patients with myositis early immunomodulation by intensive treatment ("hit-early/hit-hard" principle) may induce faster reduction of disease activity and prevent chronic disability.
- Conditions
- Inflammatory Myopathy, Idiopathic, Dermatomyositis, Antisynthetase Syndrome, Immune-Mediated Necrotizing Myopathy
- Trial name
- TIMEISMUSCLE (NCT05832034)
- Testing
- Immune Globulin Intravenous (Human)
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Muscle Function, Muscle Soreness
Vitamin D2, Muscle Damage, NASCAR Pitcrew
Hypothesis: Six weeks of supplementation with vitamin D (4000 IU/day) using Dole's Vitamin D Portobello Mushroom Powder will increase winter serum vitamin D levels, and improve muscle function and strength, and innate immunity…
- Conditions
- Muscle Function, Muscle Soreness, Vitamin D Status
- Trial name
- NCT01825616
- Testing
- Vitamin D2 mushroom powder
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Fasciitis, Plantar
Efficacy of Focused Shock Waves Combined With Adjuvant Therapy With Tendon Supplement
Physical treatment with focused shock waves is effective in the treatment of tendonitis. Food supplements could facilitate the healing of tendinopathies when combined with shock wave therapy.
- Trial name
- NCT04664712
- Testing
- Tendisulfur Pro, Focused shock wave
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
MYOPATHY
Stem Cell Transplantation in Idiopathic Inflammatory Myopathy Diseases
Myositis is a disease, believed to be due to immune cells, cells which normally protect the body, but are now attacking the muscles and other organ systems within body.
- Trial name
- NCT00278564
- Testing
- Hematopoietic stem cell transplantation, Cyclophosphamide, Mesna
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Northwestern University
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Cerebral Palsy, Spastic
The Effect of Botulinum Toxin and ESWT Applications on Spasticity and Functionality in Cerebral Palsy Patients
Cerebral Palsy (CP) is a group of movement and posture disorders associated with a non-progressive affect during brain development that can cause limitation of activity and disability.
- Trial name
- NCT05627921
- Testing
- Extracorporeal Shock Wave Therapy, Botilinum Toxin injection
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Temporomandibular Disorder (TMD), Temporomandibular Joint Pain
EMVITAL + EMFACE Combination Therapy for Temporomandibular Joint (TMJ) Pain Relief
This prospective, multi-center, open-label, single-arm clinical study will evaluate the efficacy and performance of the BTL-043 and BTL-785F devices for alleviating TMJ pain.
- Conditions
- Temporomandibular Disorder (TMD), Temporomandibular Joint Pain, Facial Pain, Neck Pain
- Trial name
- NCT07661121
- Testing
- Treatment with BTL-043 and BTL-785F
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- BTL Industries Ltd.
Fibromyalgia
Micronized and Ultramicronized Palmitoylethanolamide in Fibromyalgia Patients
The onset of chronic Fibromyalgia symptomatology is due to central alterations, together with peripheral neuroimmune modifications.
- Trial name
- NCT04488926
- Testing
- micronized and ultra-micronized Palmitoylethanolamide (mPEA and umPEA, 300mg + 600mg) microgranules, Standard Therapy, Rescue Drug
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Epitech Group SpA
Muscle Weakness
Evaluation of Effectiveness of Combining High Protein Intake With Early Physical Exercise During Critical Illness
Assessment of Effectiveness of combined high protein intake with early physical exercise by ultrasound measurement of rectus femoris muscle thickness in Intensive Care Unite mechanically ventilated patients.
- Trial name
- NCT05877989
- Testing
- Amino Acid, Physical exercise
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Lupus Erythematosus, Systemic, Foot Orthoses
Effect of Insoles in Patients With Systemic Lupus Erythematosus
Demonstrate that custom-made insoles improve painful symptomatology, health and foot function in subjects with SLE and podiatric involvement.
- Conditions
- Lupus Erythematosus, Systemic, Foot Orthoses, Musculoskeletal Pain
- Trial name
- EISLE (NCT04098055)
- Testing
- Custom-Made Foot Orthoses
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Seville
De Quervain's Tenosynovitis
Analyze the Comparison of the Effectiveness of Kinesio ®and Dynamic Taping for De Quervain's Tenosynovitis
_De Quervain's tenosynovitis is inflammation and swelling of the tendon caused by repetitive thumb movements. In severe cases, the tendon sliding is limited, resulting in limited joint range of motion and affecting the quality of…
- Trial name
- NCT07062276
- Testing
- Dynamic taping, Kinesio ®
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
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