Clinical trials: Myopathies
Musculoskeletal Pain
Ultrasonographic Parameters and Life Quality in Nocturnal Shoulder Pain
This study aimed to investigate the effects of nocturnal pain on clinical and ultrasonographic parameters in patients with rotator cuff tendinopathy.
- Trial name
- NCT03466307
- Testing
- Ultrasonography
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Tissue Injury, Major Trauma
Markers of Tissue Injury and Rhabdomyolysis in Patients With Major Trauma
Major trauma is associated with a release of alarmins (DAMPs - damage-associated molecular patterns) from the injured tissues. This process results in the activation of the immune system, which is one of the main mechanisms…
- Conditions
- Tissue Injury, Major Trauma, Rhabdomyolysis
- Trial name
- NCT03986736
- Testing
- Laboratory analysis - upon admission, Laboratory analysis - 24 hours after injury
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Ostrava
Atrophy, Muscular
31P MRS Ischaemic Exercise Optimisation and COPD
An MRI study to develop a reliable methodology for 31P MRS ischaemic exercise in order to obtain a consistent standard of measurement of muscle metabolism while maintaining an acceptable level of subject comfort and use optimised…
- Trial name
- NCT01476072
- Testing
- MRI scan
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fibromyalgia
Pranayama and Diaphragmatic Breathing Exercise Applied to Female Patients With Fibromyalgia
Female patients diagnosed with fibromyalgia were divided into pranayama breathing exercise, diaphragm breathing exercise and control groups.
- Trial name
- NCT05840939
- Testing
- Pranayama, diaphragm breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Fibromyalgia
Investigation of the Effectiveness of Thoracic Mobilization Exercise in Fibromyalgia Patients
The aim of this study is to investigate the effects of mobilization exercises applied to the thoracic region on pain, anxiety, depression, disease impact questionnaire, sympathetic and parasympathetic activity in patients…
- Trial name
- NCT06415565
- Testing
- conventional physiotherapy, thoracic mobilization methods
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Fibromyalgia
Heart Rate Variability in Fibromyalgia - Effects of Strengthening Exercises
Abstract Objective: Autonomic dysfunction is an important mechanism that could explain many symptoms observed in fibromyalgia (FM).
- Trial name
- NCT02004405
- Testing
- strengthening exercise, flexibility exercise
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Espirito Santo
Spastic Cerebral Palsy
Knee Joint Angle Affect Muscle Architecture in Children With Cerebral Palsy
To determine if there is an effect of knee joint angle on muscle architecture in children with spastic cerebral palsy
- Trial name
- NCT06481722
- Testing
- cerebral palsy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Duchenne Muscular Dystrophy (DMD)
Twice Weekly Steroids and Exercise as Therapy for DMD
The study team will determine the potential of low dose twice weekly prednisone and whether exercise training can synergize to delay disease progression and improve muscle strength/physical function in boys with Duchenne muscular…
- Trial name
- NCT04322357
- Testing
- Prednisone, Exercise Training on standard steroid regimen, Exercise training on twice-weekly steroids
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Florida
Temporomandibular Disorders (TMD)
INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR
Temporomandibular disorders (TMD) encompass all temporomandibular muscular and osteoarticular conditions. TMD affects 31% of the adult population, with chronic, debilitating pain in 10% of cases.
- Trial name
- DiagDTM (NCT07499869)
- Testing
- digital jaw impressions and Modjaw® records
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Congenital Myotonic Dystrophy
Tideglusib: Expanded Access Use in Congenital Myotonic Dystrophy
This treatment plan is limited to a single patient with Congenital Myotonic Dystrophy, who is ineligible or otherwise unable to participate in ongoing clinical trials.
- Trial name
- NCT07119775
- Testing
- Tideglusib
- Sponsor
- AMO Pharma Limited
Fibromyalgia, Primary, Fibromyalgic Sindrome
Fibromyalgia Different Approaches: Acupuncture vs Migratens
Fibromyalgia or Fibromyalgic Sindrome (FMS) is a chronic debilitating pain syndrome, characterized by widespread chronic musculoskeletal pain and generalized painful hypersensitivity, which may be associated with systemic…
- Trial name
- FrIDAy (NCT04098757)
- Testing
- Migratens
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Vittorio Schweiger
Pediatrics, Muscle Spasticity
BOTOX® Treatment in Pediatric Lower Limb Spasticity
This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with lower limb spasticity.
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy
- Trial name
- NCT01603628
- Testing
- botulinum toxin Type A
- Where
- 53 sites in United States, Hungary and 7 more
- Volunteers
- 384 people
- Sponsor
- Allergan
Chronic Fatigue Syndrome
Discovering Trends in Chronic Fatigue Syndrome Patients' Clinical Study Experiences
The study seeks to delve into the firsthand experiences of patients diagnosed with chronic fatigue syndrome who partake in a separate clinical trial featuring a specific medical intervention.
- Trial name
- NCT05967494
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Duchenne Muscular Dystrophy
An Open-Label Extension Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy
The GalaxyDMD study is a global Phase 3, open-label, treatment extension study to evaluate the safety, tolerability, and durability of effect in long-term dosing of edasalonexent in pediatric patients with a genetically confirmed…
- Trial name
- GalaxyDMD (NCT03917719)
- Testing
- Edasalonexent
- Where
- 23 sites in United States, Australia and 4 more
- Volunteers
- 130 people
- Sponsor
- Catabasis Pharmaceuticals
Music
Study Strategies in Musicians and Their Relationship With Physical and Emotional Variables
The musician profession requires great efforts not only at job level, also social, mental and physical level from the beginning of musical studies.
- Trial name
- SSMmusic (NCT05503472)
- Testing
- observational
- Where
- Spain
- Volunteers
- 94 people
- Sponsor
- University of Valencia
Fibromyalgia
Maintenance of Efficacy.
The hypothesis of Study A6061054 is to demonstrate superiority of efficacy of esreboxetine at 3 and 6 months compared to placebo.
- Trial name
- NCT00796601
- Testing
- Esreboxetine
- Sponsor
- Pfizer
Temporomandibular Joint and Muscle Disorder
An Implementation and Biobehavioral Study of Temporomandibular Joint and Muscle Disorder (TMJMD)
With the great economic costs and traditionally poor outcomes among chronic temporomandibular joint and muscle disorder (TMJMD) patients, it has become important to treat patients in the acute state, in order to prevent these…
- Trial name
- NCT00952900
- Testing
- Biobehavioral, Active Coping/Attention Intervention
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
TMJ Disorder
MESNA Injection for TMJ Internal Derangement
The pathogenesis of temporomandibular disorders focusing on the biochemistry of the synovial fluid in various stages of temporomandibular joint disease.
- Trial name
- NCT05882604
- Testing
- Mesna Injection, Arthrocentesis with ringer solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Myofascial Pain Syndrome
Effect of Kinesiotaping on Myofascial Pain Syndrome Post Neck Dissection Surgery
The purpose of the study is to evaluate the effect of Kinesio taping on myofascial pain syndrome post neck dissection surgery.
- Trial name
- NCT05265884
- Testing
- Kinesiotaping, traditional therapy intervention
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Muscle Weakness, Pulmonary Arterial Hypertension
Transforming Growth Factor Beta Signalling in the Development of Muscle Weakness in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a disease that causes raised blood pressure in blood vessels that pick up oxygen from the lungs. It has a life expectancy similar to some cancers.
- Trial name
- NCT01847716
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Imperial College London
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