Clinical trials: Myopathies
Duchenne Muscular Dystrophy, Muscular Dystrophies
Non-invasive Imaging of Muscle Structure in Duchenne Muscular Dystrophy Using Multispectral Optoacoustic Tomography
This pilot study aims to assess subcellular muscle structure in patients with Duchenne X-linked progressive Duchenne muscular dystrophy (DMD) in comparison to healthy volunteers using multispectral optoacoustic tomography (MSOT).
- Conditions
- Duchenne Muscular Dystrophy, Muscular Dystrophies, Muscular Dystrophy, Duchenne
- Trial name
- MSOT_DMD (NCT03490214)
- Testing
- Multispectral Optoacoustic Tomography
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chronic Brain Injury, Cerebral Stroke
Qualitative Study Patient & Physician Experiences Botox COVID-19
During the COVID-19 pandemic and subsequent series of Lockdowns, clinic out-patient spasticity services were replaced with video based tele-consultation appointments, in order to reduce the potential risk of virus transmission…
- Conditions
- Chronic Brain Injury, Cerebral Stroke, MS (Multiple Sclerosis)
- Trial name
- QualBotoxCov (NCT05435404)
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Fibromyalgia
Evaluation of the Effectiveness of a Psychological Intervention for Fibromyalgia Supported by New Technologies
This study aims to evaluate the feasibility of a psychological intervention in patients diagnosed with Fibromyalgia supported by new technologies.
- Trial name
- NCT07347704
- Testing
- Cognitive Behavioral Therapy with app suport
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universitat Jaume I
Cerebral Palsy, Hypertonia
Use of EMG to Assess Clinical Hypertonia
A handheld surface electromyography device will be tested by clinicians on children with limb hypertonia, and inter-rater reliability will be assessed with and without the device.
- Conditions
- Cerebral Palsy, Hypertonia, Spasticity, Dystonia
- Trial name
- NCT00472914
- Testing
- portable surface electromyography
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Neuromuscular Diseases in Children, Respiratory Function Impaired
Respiratory Functions, Thoracoabdominal Movements and Exercise Capacity in Neuromuscular Diseases
The clinical trial titled "Investigation of Respiratory Functions, Thoracoabdominal Movements, and Exercise Capacity in Neuromuscular Diseases" aims to evaluate the respiratory functions, thoracoabdominal movements, and exercise…
- Conditions
- Neuromuscular Diseases in Children, Respiratory Function Impaired, Respiratory Insufficiency, Duchenne Muscular Dystrophy
- Trial name
- NCT06756633
- Testing
- Respiratory Function Test, Structured light plethysmography, 6 Minute Walking Test
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Fibromyalgia
Whole-Body Cryotherapy (WBC) as an Adjunct Treatment on Pain in Fibromyalgia Persons: Short Time Effect.
Our aim was to determine whether Whole Body Cryotherapy (WBC) can result in improved pain status, perceived health, and quality of life in patients with fibromyalgia.
- Trial name
- NCT03466008
- Testing
- Whole-Body Cryotherapy
- Volunteers
- 24 people
- Sponsor
- Haute École Robert Schuman Libramont
Sporadic Inclusion Body Myositis
Efficacy and Safety of Bimagrumab/BYM338 at 52 Weeks on Physical Function, Muscle Strength, Mobility in sIBM Patients
This study evaluated the efficacy, safety and tolerability of multiple doses of bimagrumab/BYM338 vs placebo, when administered intravenously (i.v.), on physical function, muscle strength, and mobility in patients with sporadic…
- Trial name
- RESILIENT (NCT01925209)
- Testing
- BYM338/bimagrumab
- Where
- 38 sites in United States, Australia and 8 more
- Volunteers
- 251 people
- Sponsor
- Novartis Pharmaceuticals
Fibromyalgia, Cognition
Factors Associated With Cognitive Skills in Patients With Fibromyalgia
The aim of this study was to identify factors associated with cognitive skills in female patients with fibromyalgia.
- Trial name
- NCT07662993
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Zülal TATAR
Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain
Pain Phenotype and Response to Corticosteroid Injection in Patients With Subacromial Pain Syndrome (SAPS)
The goal of this prospective cohort study is to investigate whether pain phenotype is associated with subsequent change in pain intensity after corticosteroid injection given as part of routine care in patients diagnosed with…
- Conditions
- Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain, Shoulder Pain, Shoulder Impingement Syndrome
- Trial name
- NAP SAPS CSI (NCT07792421)
- Testing
- Clinical evaluation
- Where
- Denmark
- Volunteers
- 134 people
- Sponsor
- Vejle Hospital
Temporomandibular Disorders, Headache
The BETY-Biopsychosocial Questionnaire (BETY-BQ) in Individuals With Temporomandibular Dysfunction-Related Headache
This study investigates the validity and reliability of the BETY- Biopsychosocial Questionnaire (BETY-BQ) as a biopsychosocial assessment tool in individuals with temporomandibular dysfunction-related headaches.
- Trial name
- NCT05902026
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hasan Kalyoncu University
Trigger Point Pain, Myofascial
Comparison of Ischemic Release and Sustained Pressure Direct Myofascial Release in Upper Trapezius Trigger Point
This randomized controlled trial aims to compare the clinical effectiveness of ischemic release and sustained pressure direct myofascial release for upper trapezius trigger points.
- Trial name
- NCT07838584
- Testing
- Ischemic release, Sustained pressure Direct Myofascial release
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Foundation University Islamabad
Fibromyalgia Syndrome, Fibromyalgia
Effects of 2-Aticyto Complex and D-Ribose on Pain and Clinical Course in Patients With Fibromyalgia
This multicenter, randomized, double-blind, placebo-controlled study will evaluate whether an oral supplement containing 2-Aticyto Complex and D-ribose (FibroThol), added to ongoing standard medical treatment, improves pain…
- Trial name
- NCT07495943
- Testing
- 2-Aticyto Complex and D-ribose Oral Supplement
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Duchenne Muscular Dystrophy
Aerobic Exercise in Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy (DMD) is the most common neuromuscular disease in childhood with an estimate incidence of 1 in 3500 to 5000 male births.
- Trial name
- NCT04173234
- Testing
- Aerobic Training, Home exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Hacettepe University
Myocarditis, ANCA Associated Vasculitis
EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases
Inflammatory Cardiovascular Diseases and Autoimmune Rheumatic Diseases (ICARDs) encompass cardiovascular involvement in connective tissue diseases, vasculitis, and primary inflammatory cardiac processes affecting all layers of…
- Conditions
- Myocarditis, ANCA Associated Vasculitis, Pericarditis, Systemic Sclerosis
- Trial name
- EACVI-INFLAME (NCT07077304)
- Testing
- observational study
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Herniated Disk, Temporomandibular Disorders
Randomized Clinical Trial of Treatment for Temporomandibular Joint (TMJ) Disc Displacement
The effectiveness of physical therapy for treatment of anterior disc displacement without reduction of temporomandibular disorders has not been well defined.
- Trial name
- NCT00936338
- Testing
- splint and joint mobilization self exercise
- Where
- Japan
- Volunteers
- 44 people
- Sponsor
- Tokyo Medical and Dental University
Fibromyalgia
Study of the Symptomatic Improvement in Patients With Fibromyalgia by Means of a Food Supplement
Fibromyalgia is a syndrome (set of symptoms) of unknown etiology and characterized by diffuse musculoskeletal pain and chronic fatigue.
- Trial name
- FIBROFIN (NCT05718908)
- Testing
- Food supplement
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Arafarma Group, S.A.
Lateral Epicondylitis, Lateral Epicondylitis, Left Elbow
Doxycycline for Elbow Tendinopathy
To evaluate the feasibility of subantimicrobial -dose (SD) doxycycline to improve outcomes of nonsurgical management of elbow tendinopathy via matrix metalloproteinase (MMP) inhibition as well as evaluate if participants will be…
- Conditions
- Lateral Epicondylitis, Lateral Epicondylitis, Left Elbow, Lateral Epicondylitis, Right Elbow, Lateral Epicondylitis, Unspecified Elbow
- Trial name
- NCT04686799
- Testing
- Doxycycline Hyclate 20 MG
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Hospital for Special Surgery, New York
Nonaka Myopathy, Hereditary Inclusion Body Myopathy
Pharmacokinetic Study on N-acetylneuraminic Acid
The aim of this study is to investigate pharmacokinetics and safety of N-acetylneuraminic acid in patients with Distal myopathy with rimmed vacuoles (DMRV) - hereditary inclusion body myopathy (hIBM).
- Trial name
- NCT01236898
- Testing
- NPC-09
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Tohoku University
Multiple Sclerosis, Fatigue Syndrome, Chronic
Chronic Fatigue in Multiple Sclerosis: MS Copilot Boost Solution Compared to Standard Care
The main objective of the MS Boost study is to demonstrate the superiority of MSCopilot Boost over standard practice in reducing the impact of fatigue on Patients with Multiple Sclerosis (MS).
- Trial name
- MSBoost (NCT06386133)
- Testing
- MS Boost, Standard of care
- Volunteers
- 208 people
- Sponsor
- Ad scientiam
Muscle Pain, Joint Pain
Prevalence of Muscle and Nerve and Joint Pain
The purpose of the study is to provide adequate information about the percentage of the main tissue that causing pain in most common spinal disorders either it is muscular, nerve or joint in each spinal parts, that will provide…
- Conditions
- Muscle Pain, Joint Pain, Nerve Pain
- Trial name
- NCT06402448
- Testing
- muscle pain , joint pain and nerve pain.
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Hadeer Gomaa Ebraheem Aly
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