Clinical trials: Myopathies
Parkinson Disease, Tremor, Limb
Effects of a Dynamic Upper Limb Orthosis in Patients With Parkinson's Disease
This is a randomized controlled clinical trial aimed at Parkinson's disease patients. Its objective is to evaluate the effects of a dynamic upper limb orthosis to achieve maximum hand functionality, reducing tremor and rigidity
- Conditions
- Parkinson Disease, Tremor, Limb, Rigidity, Muscle
- Trial name
- NCT04815382
- Testing
- Dynamic Upper Limb Orthosis
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Burgos
Temporomandibular Disorder
Cervical Spine Thrust Joint Manipulation for Temporomandibular Disorder
Background: Temporomandibular disorder (TMD) is a common and costly problem that often leads to chronic pain or dysfunction. There is moderate evidence to support physical therapy (PT) interventions for individuals with TMD, yet…
- Trial name
- NCT03300297
- Testing
- Cervical Spine Thrust Joint Manipulation, Home Program, Suboccipital Release
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Bradley University
Achilles Tendon, Tendinopathy
Eccentric Training and Cryotherapy Vs Eccentric Training and Whole Body Vibration in Achilles Tendinopathy
The purpose of this study is to determine the effectiveness of eccentric exercise combined with vibration or cryotherapy in Achilles tendon pathology.
- Trial name
- NCT03029910
- Testing
- Cryotherapy and eccentric exercise, Vibration and eccentric exercise
- Where
- Spain
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Fibromyalgia
Laughter Frequency and Fibromyalgia Symptoms
The purpose of this study is to investigate whether daily laughter frequency is associated with pain intensity and emotional state ratings in individuals who have fibromyalgia syndrome.
- Trial name
- LAF (NCT02957110)
- Testing
- Laughter Frequency
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Walden University
Inflammation In Skeletal Muscle
Natural History of Inflammatory Muscle Diseases
Objective: To collect information and biospecimens (such as blood, muscle, and skin samples) that will be used to research causes and treatments of inflammatory muscle diseases.
- Trial name
- NCT05738824
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Breast Cancer, Chemotherapy Effect
Effects of Creatine Supplementation in Breast Cancer Survivors
The purpose of this study is to test the hypothesis that creatine will accelerate adaptations associated with exercise in breast cancer survivors recently completing chemotherapy.
- Conditions
- Breast Cancer, Chemotherapy Effect, Muscle Weakness, Muscle Loss
- Trial name
- NCT04207359
- Testing
- Creatine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Fibromyalgia
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
The study is a Phase 3, double-blind, placebo-controlled, randomized withdrawal study to assess the efficacy and safety of AXS-14 in the management of fibromyalgia.
- Trial name
- FORWARD (NCT07398417)
- Testing
- AXS-14 (Esreboxetine)
- Where
- 53 sites in United States
- Volunteers
- 620 people
- Sponsor
- Axsome Therapeutics, Inc.
Fatigue Syndrome, Chronic, Cold
Effectiveness of Antrodia Cinnamomea Mycelia on Improving Immune Response in Subhealth People
This study aims to assess the effect of Antrodia cinnamomea mycelia on immune modulation in subhealth people.
- Trial name
- NCT05728918
- Testing
- Antrodia cinnamomea mycelia
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Greenyn Biotechnology Co., Ltd.
Musculoskeletal Pain
vEAET for Older Veterans With Chronic Musculoskeletal Pain Pilot
An uncontrolled pilot in which Veterans age 60-95 years with chronic musculoskeletal (MSK) pain will undergo Emotional Awareness and Expression Therapy (EAET) delivered over video teleconference (VTC; together vEAET).
- Trial name
- vEAET (NCT04552860)
- Testing
- Emotional Awareness and Expression Therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Duchenne Muscular Dystrophy
Upper Limb Assessment in Duchenne Muscular Dystrophy
The literature on outcome measures assessing upper limbs in Duchenne muscular dystrophy (DMD) is quite scanty. While there have been considerable advances for ambulant DMD boys, no prospective study has so far been devoted to…
- Trial name
- PUL in DMD (NCT02436720)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Catholic University of the Sacred Heart
Oculopharyngeal Muscular Dystrophy
Treatment of Oculopharyngeal Muscular Dystrophy With Trehalose
BB-OPMD-202 is a randomized, double-blind, placebo-controlled study of IV trehalose for treatment of OPMD. The study includes a 4-week screening period, a 24-week blinded treatment period during which patients will receive weekly…
- Trial name
- NCT04226924
- Testing
- Trehalose
- Where
- 3 sites in Canada
- Sponsor
- Bioblast Pharma Ltd.
Physical Performance, Rhabdomyolysis
The Effect of Remote Ischemic Preconditioning on Physical Performance and Exertional Rhabdomyolysis
In order to examine the effect of RIPC on skeleton muscle exertional damage and on aerobic and anaerobic physical performances, 30 healthy volunteers will undergo a series of different physical tests twice; once without…
- Trial name
- NCT02518724
- Testing
- RIPC intervention exposure
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Duchenne Muscular Dystrophy, Upper Limb Function
Pulmonary and Upper Limb Functions in Duchenne Muscular Dystrophy
Although it is known that the functions of pulmonary and upper limb is affected in late stage of Duchenne Muscular Dystrophy (DMD) negatively, the investigators do not have clear information about its early stage.
- Conditions
- Duchenne Muscular Dystrophy, Upper Limb Function, Respiratory Function Test
- Trial name
- NCT03552874
- Testing
- The Performance of Upper Limb Questionnaire (PUL)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Temporomandibular Joint Disorder
Validation and Cultural Adaptation of Jaw Functional Limitation Scale-20
Temporomandibular joint (TMJ) disorder (TMD) is common. Jaw Functional Limitation Scale-20 (JFLS) is a validated tool for the evaluation of patients suffering from TMD
- Trial name
- NCT07789197
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Fibromyalgia
Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome.
Ketamine and Esketamine intravenous perfusions can modulate chronic pain. The purpose of this study is to determine if Ketamine or Esketamine are favorable for outpatients suffering from fibromyalgia.
- Trial name
- KESK-FIQ (NCT04938713)
- Testing
- Ketamine 50 MG/ML, Esketamine 25 MG/ML
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Charleroi
Systemic Lupus Erythematosus, Cutaneous Lupus Erythematosus
A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis
The purpose of this study is to evaluate the safety and tolerability of escalating, multiple subcutaneous (SC) doses of VIB7734 in participants with Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE)…
- Conditions
- Systemic Lupus Erythematosus, Cutaneous Lupus Erythematosus, Sjogren's Syndrome, Systemic Sclerosis
- Trial name
- NCT03817424
- Testing
- VIB7734
- Where
- 30 sites in United States, Poland and 1 more
- Volunteers
- 31 people
- Sponsor
- Amgen
Studying Efficacy of dTMS in FM
dTMS as a Treatment for Patients With Fibromyalgia
Purpose: The purpose of the study is to explore the efficacy of H1 deep TMS for the treatment of FMS. Design: Prospective randomized sham controlled trial Study Population \& sample size:forty (40) FMS subjects between 18-80…
- Trial name
- NCT03460340
- Testing
- prefrontal deep rTMS of H1 Coil
- Volunteers
- 40 people
- Sponsor
- Shalvata Mental Health Center
Neuropathic Pain, Fibromyalgia
Deep rTMS (H-coil) for Neuropathic Pain or Fibromyalgia
This study will investigate the efficacy and safety of "deep" rTMS on neuropathic pain or fibromyalgia. It will be randomized and sham controlled and will last 3 months.
- Trial name
- H-FINEP (NCT06250491)
- Testing
- Deep active rTMS with Hesed coil
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Nadine ATTAL
Pain, Stomatognathic Diseases
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
- Conditions
- Pain, Stomatognathic Diseases, Muscle Hypertonia, Myofacial Pain Syndromes
- Trial name
- NCT05021874
- Testing
- Four different physiotherapy treatment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Musculoskeletal Pain, Physical Performance
Kinesiophobia and Physical Function in Elderly With Musculoskeletal Pain
This study aims to investigate how kinesiophobia (fear of movement), pain intensity, and physical performance are related in older adults experiencing musculoskeletal pain.
- Conditions
- Musculoskeletal Pain, Physical Performance, Geriatrics, Kinesiophobia
- Trial name
- NCT07272876
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
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