Clinical trials: Myopathies
Myofascial Pain Syndrome (MPS)
Effects of Electrical Muscle Stimulation on Myofascial Pain Syndrome
The goal of this clinical trial is to determine if Electrical Muscle Stimulation (EMS) combined with Active Stretching (AS) (EMS+AS) and EMS+AS combined with Trigger Point Pressure Release (TPR) (EMS+AS+TPR) are effective…
- Trial name
- NCT07315776
- Testing
- Therapist-assisted Passive stretching (PS), The two-combination of EMS+AS, Trigger point pressure release (TPR)
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- University of Bath
Pain, Analgesics
Mentholated Cream Containing Oxygenated Glycerol Triesters on Acute Pain of the Muscles and Joints
A single center trial to evaluate the efficacy, tolerance, and acceptability of Oxygenated Glycerol Triesters (OGT) mentholated cream on acute musculoskeletal pain in normal healthy adult volunteers suffering from a recent…
- Trial name
- NCT01387750
- Testing
- Mentholated Cream, Mentholated Cream with OGT
- Volunteers
- 71 people
- Sponsor
- NEMA Research, Inc.
Fibromyalgia
Effectiveness of Acupuncture in Relieving Pain Due to Fibromyalgia
This study will determine the effectiveness of acupuncture versus a placebo in altering brain activity and relieving pain due to fibromyalgia.
- Trial name
- NCT00142597
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Michigan
Spinal Cord Injuries
The Effects of Spasticity on Glucose Metabolism in Individuals With Spinal Cord Injury
Muscle atrophy may occur in individuals with spinal cord injury (SCI) as a result of diminished physical activity and alterations in glucose metabolism and body composition may be seen.
- Trial name
- NCT03859960
- Testing
- body composition, glucose, insulin, glycohemoglobin
- Volunteers
- 33 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Chronic, Fibromyalgia
Pain Neuroscience Education in Patients with Fibromyalgia
Many patients with fibromyalgia have little understanding of their condition, leading to maladaptive pain cognitions and coping strategies.
- Trial name
- NCT04050839
- Testing
- Pain neuroscience education, Medical treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Tennis Elbow
Effect of Premodulated Current Versus Diadynamic Current On the Management of Tennis Elbow.
104 patients with unilateral tennis elbow from both genders (57 females and 43 males) referred by orthopaedist with age ranged between 20 and 60 years.
- Trial name
- NCT05084664
- Testing
- electrical stimulation
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- October 6 University
Myofascial Pain Syndrome, Temporomandibular Joint Disorders
Comparison of Lidocaine, Mepivacaine, and Dry Needling in Myofascial Pain Syndrome
This randomized clinical trial will aim to compare the effectiveness of dry needling, lidocaine injection, and mepivacaine injection in the treatment of myofascial pain in the masticatory muscles.
- Conditions
- Myofascial Pain Syndrome, Temporomandibular Joint Disorders, Facial Pain
- Trial name
- NCT07079449
- Testing
- Dry Needling, Lidocaine Hydrochloride, Mepivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Sümer Münevveroğlu
Muscle Weakness, Muscle Atrophy
Effect of Neuromuscular Electrical Stimulation Combined With Blood Flow Restriction on Muscular and Cardiovascular Function
Neuromuscular electrical stimulation (NMES) has recently been combined with blood flow restriction (BFR) in controlled trials and has shown increased muscular strength and size compared with NMES and BFR on their own.
- Trial name
- NCT03662555
- Testing
- Neuromuscular electrical stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Hypovitaminosis D, Hand Grasp
Vitamin D and Hand Grip Strength at 5 Years in Odense Child Cohort
This study will encompass an analysis of an eventual association between vitamin D status (maternal during pregnancy, at birth or at 5 years) and hand grip strength at 5 years in children from Odense Child Cohort.
- Conditions
- Hypovitaminosis D, Hand Grasp, Children
- Trial name
- VITHGS (NCT03381378)
- Volunteers
- 881 people
- Sponsor
- Odense University Hospital
Arthritis, Polymyalgia Rheumatica
A Qualitative Assessment of the Severity and Impact of Rheumatic Immune-Related Adverse Events Following Immune Checkpoint Inhibitor Immunotherapy
To understand the severity and nature of participants experiences during irAEs following immune checkpoint inhibitor immunotherapy.
- Conditions
- Arthritis, Polymyalgia Rheumatica, Immune Checkpoint Inhibitors
- Trial name
- NCT06647134
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Patella; Tendinitis
Protein Turnover in Healthy and Overuse-diseased Tendon
The goal of this clinical trial is to examine the regional protein turnover in tendon tissue from patients with chronic patellar tendinopathy and comparing this to healthy controls.
- Trial name
- NCT05776485
- Testing
- Progressive resistance training, Cross-sectional comparison between healthy and tendinopathic group
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Temporomandibular Disorder
Safety and Efficacy of Erenumab-aooe in Patients With Temporomandibular Disorder
The purpose of this proof of concept study is to evaluate the safety and efficacy of the off-label use of Aimovig® (EREN) in reducing Temporomandibular Disorder (TMD) pain compared to placebo.
- Trial name
- NCT04884763
- Testing
- Erenumab-aooe (EREN) 140 mg s.c. administered every four weeks for a total of five treatments
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Lateral Epicondylitis
Comparison of Peloidotherapy and Extracorporeal Shock Wave Therapy Efficiency in Patients With Lateral Epicondylitis
Investigator could not find a study comparing ESWT(Extracorporeal Shock Wave Therapy) and Peloidotherapy methods in the treatment of lateral epicondylitis in the literature.
- Trial name
- NCT04748406
- Testing
- Extracorporeal Shock Wave Therapy(ESWT), Peloid therapy, Home Workout Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Konya Meram State Hospital
Fibromyalgia
A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL Taken Daily in Patients With Fibromyalgia
This is a Phase 3, randomized, parallel-group, double-blind, placebo-controlled, 14-week study designed to evaluate the efficacy and safety of TNX-102 SL 5.6 mg (2 x 2.8 mg tablets) taken daily at bedtime for the treatment of…
- Trial name
- RESILIENT (NCT05273749)
- Testing
- TNX-102 SL Tablet, 5.6 mg
- Where
- 33 sites in United States
- Volunteers
- 457 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Mitochondrial Myopathy
Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy
Phase 1/2, multi-center, randomized, double-blind, multiple ascending dose, placebo-controlled study that enrolled 36 subjects with mitochondrial myopathy associated with genetically confirmed mitochondrial disease to evaluate…
- Trial name
- MMPOWER (NCT02367014)
- Testing
- elamipretide (low dose), elamipretide (intermediate dose), elamipretide (high dose)
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Stealth BioTherapeutics Inc.
Gulf War Illness, Persian Gulf Syndrome
Exercise in Gulf War Illness (GWI)
The purpose of this study is to determine if submaximal exercise by bicycle stress tests with pulmonary measurement of VO2MAX plus maximal isometric hand grips on 2 consecutive days causes a higher level of "exertional…
- Trial name
- NCT01291758
- Testing
- Submaximal bicycle exercise stress tests performed 24 hr apart
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Spasticity, Muscle, Stroke
Effects of Using the Electrodress Mollii on Spasticity
Spasticity is a common manifestation of lesions of central motor pathways, such as after stroke, traumatic brain or spinal cord injury and in cerebral palsy and is associated with increased impairments and disabilities.
- Conditions
- Spasticity, Muscle, Stroke, Electric Stimulation Therapy
- Trial name
- NCT04076878
- Testing
- Mollii
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Danderyd Hospital
Muscle Weakness, Cervical Disability
Effectiveness of a Training Protocol With the Cervical Device in Subjects With Deep Cervical Muscle Strength Deficit.
The purpose of this study is to evaluate the clinical results produced by a training protocol with the new device for cervical treatment (CDAT) and the conventional training protocol (CT) versus a control group (C) in subjects…
- Trial name
- NCT05288712
- Testing
- Training protocol with the device cervical for treatment (CDAT), Conventional training protocol
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Universitat Internacional de Catalunya
Fibromyalgia, Irritable Bowel Syndrome
Exercise, Irritable Bowel Syndrome and Fibromyalgia
The project focuses on "somatic functional syndrome", a category of disorders characterized by subjective symptoms, suffering and disability without evident organic or functional alterations.
- Trial name
- AF-IBS-FM (NCT06166563)
- Testing
- Exercise Program
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Fibromyalgia
Validity and Reliability of the 2-minute Step Test in Patients With Fibromyalgia
The objective of this study was twofold: first, to assess the validity and reliability of the 2 Minute Step Test (2MST) in patients with fibromyalgia; and second, to explore its relationship with objective assessment methods…
- Trial name
- NCT06061016
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
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