Clinical trials: Myopathies
Lateral Epicondylitis, Pain
The Effects of Radial and Focused Extracorporeal Shock Wave Therapies on Lateral Epicondylitis
To date, focused and radial types of extracorporeal shock wave therapy have been effectively used in lateral epicondylitis. However, studies directly addressing a comparison between radial and focused types of extracorporeal…
- Trial name
- NCT04838002
- Testing
- Extracorporeal shock wave
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Şeyhmus KAPLAN
Ear Protective Devices, Temporomandibular Joint Disorders
The Use of Earplugs on Temporomandibular Joint
The term temporomandibular joint disorder (TMD) refers to a group of disorders affecting the temporomandibular joint and/or muscles of mastication. Typical symptoms are; joint noises, pain, and limited mouth opening.
- Conditions
- Ear Protective Devices, Temporomandibular Joint Disorders, Physical Therapy Modalities
- Trial name
- NCT05362877
- Testing
- Earplug, occlusal splint, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Fibromyalgia
Repetitive Transcranial Magnetic Stimulation in Fibromyalgia
The purpose of this study is to determine the analgesic effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) used as an additional procedure to rehabilitation exercises in patient suffering from fibromyalgia.
- Trial name
- STIMALGI (NCT01308801)
- Testing
- active rTMS + rehabilitation exercise
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Grenoble
Hypogonadism, Male, Fatigue Syndrome, Chronic
Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone
The overall goal of this study is to evaluate the effect of a testosterone drug called Depo-Testosterone (or 'testosterone cypionate'), an FDA-approved drug for improving fatigue, sexual function, quality of life, body…
- Trial name
- NCT04049331
- Testing
- Testosterone Undecanoate 750 MG/3 ML Intramuscular Solution [AVEED]
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Achilles Tendinopathy, Achilles Tendon Enthesopathy
Treatment for Achilles Tendinopathy
The purpose of this study is to determine whether sclerotherapy using a 25% dextrose and 1% lidocaine solution is an efficacious treatment for patients with chronic Achilles tendinopathy who have failed a home based, heavy load…
- Conditions
- Achilles Tendinopathy, Achilles Tendon Enthesopathy, Mid-Portion Achilles Tendinopathy, Insertional Achilles Tendinopathy
- Trial name
- NCT00835939
- Testing
- 25% Dextrose and 1% Lidocaine, Lidocaine, sclerotherapy
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Temporomandibular Joint Dysfunction Syndrome
Efficacy of Low Level LASER Therapy in Treating Temporomandibular Muscle Disorders
This study aimed to evaluate the sustainability of the efficacy of using low level laser therapy and CAD/CAM Michigan splint in improving the range of mandibular movements, muscle activity and reducing the pain.
- Trial name
- RCT (NCT05901701)
- Testing
- Low Level LASER therapy, Hard occlusal splint
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Intensive Care (ICU) Myopathy
Intermittent Versus Continuous Feeding in ICU Patients
The purpose of this study is to determine whether intermittent nasogastric enteral feeding, rather than conventional continuous enteral feeding, will preserve muscle mass in the critically ill (Primary end-point).
- Trial name
- NCT02358512
- Testing
- Enteral feeding
- Where
- 2 sites in United Kingdom
- Volunteers
- 127 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Adrenal Insufficiency, Polymyalgia Rheumatica
Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency
In this double-blinded randomised placebo-controlled clinical trial, the aim is to determine the effect of supplemental hydrocortisone compared with placebo during mild to moderate physical or mental stress on health related…
- Conditions
- Adrenal Insufficiency, Polymyalgia Rheumatica, Giant Cell Arteritis
- Trial name
- RESCUE (NCT05435781)
- Testing
- Hydrocortisone
- Where
- 3 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- Marianne Christina Klose
Dermatomyositis, Polymyositis
Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis
The purpose of this multi-center pilot study is to determine if the drug tocilizumab (Actemra) is effective in the treatment of patients with refractory adult polymyositis (PM) and dermatomyositis (DM).
- Trial name
- TIM (NCT02043548)
- Testing
- tocilizumab
- Where
- 7 sites in United States
- Volunteers
- 36 people
- Sponsor
- Chester Oddis
Arthritis
Evaluation of Walk With Ease in Arthritis
The overall goal of this study is to determine the whether the Walk with Ease (WWE) program in its 2 version (group-assisted and self-directed) can increase physical activity and fitness levels among individuals (18 years and…
- Trial name
- WWE (NCT00526435)
- Testing
- Walk with Ease - Group, Walk with Ease - Self
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- Centers for Disease Control and Prevention
Osteoarthritis, Back Pain
Investigation of the Cultural Adaptation, Validity, and Reliability of the Turkish Version of the CAP Questionnaire
The "CAP questionnaire," developed by modifying the CAP-Knee questionnaire to assess potential nociplastic pain features in painful musculoskeletal disorders, has been described.
- Conditions
- Osteoarthritis, Back Pain, Fibromyalgia
- Trial name
- NCT06825650
- Testing
- Questionnaire study
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Hacettepe University
Fibromyalgia
Study of Mattress Type in Fibromyalgia
The purpose of this research study is to determine if a new mattress relieves the symptoms of fibromyalgia and improves sleep, and if this is the case, whether one type of mattress is better than the other in doing so.
- Trial name
- NCT01108718
- Testing
- Tempur-Pedic Mattress (2 months), Control Mattress (2 months)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Beth Israel Medical Center
Duchenne Muscular Dystrophy
Natural History of Duchenne Muscular Dystrophy Cardiomyopathy (DMD-CMP)
The purpose of this study is to describe the progression of tissular and functional myocardial abnormalities in patients with Duchenne muscular dystrophy using cardiac magnetic resonance imaging and blood biomarkers assays.
- Trial name
- DMD-CMP (NCT05558813)
- Testing
- Cardiac MRI, Blood assays
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fibromyalgia
Efficacy and Tolerability of CELERGEN in Fibromyalgia
Celergén® is a dietary supplement with anti-inflammatory and antioxidant properties composed of marine sperm extract, hydrolyzed collagen, CoQ10, lutein and selenium.
- Trial name
- NCT03911882
- Testing
- Celergen Administration
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Celergan SA
Tendinopathy
Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles Tendinopathy
This is a prospective single blinded randomised controlled trial with a 12-week intervention period and a half-year follow-up period.
- Trial name
- NCT02732782
- Testing
- Isometric exercise, Eccentric exercise
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Humboldt-Universität zu Berlin
Fibromyalgia (FM)
Effects of Curcumin-Piperine Supplementation in Fibromyalgia
The goal of this clinical trail is to evaluate the effectiveness and safety of curcumin-piperine supplementation in patients with fibromyalgia over 3 months compared to placebo.
- Trial name
- NCT07753018
- Testing
- Curcumin - Piperine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Trigger Point Pain, Myofascial
Safe Zone in Trigger Point Injection
The goal of this observational study is to define the safe distance that will reduce the risk of pneumothorax through ultrasonographic imaging measurements in both sitting and prone positions to ensure patient safety during these…
- Trial name
- NCT06664359
- Testing
- Ultrasound guided injection with local anaestethic
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people
- Sponsor
- Ankara University
Fibromyalgia
Comparison of Ba-Duan-Jin and Pregabalin in Patients with Fibromyalgia
Fibromyalgia is a chronic debilitating musculoskeletal pain syndrome. Pregabalin is the only medication that has been approved to treat fibromyalgia in China.
- Trial name
- NCT03797560
- Testing
- Ba-Duan-Jin, Pregabalin capsule
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Critical Illness Myopathy, Myopathy Critical Illness
Understanding the Mechanisms of Critical Illness Myopathy by Use of a Novel Electrophysiological Method - MVRCs
Critical illness myopathy (CIM) is a disabling condition that develops in critically ill patients. The syndrome is not only a cause of prolonged intensive care hospitalisation but also a main reason for delayed recovery.
- Trial name
- NCT04711070
- Where
- 2 sites in Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sándor Beniczky
Fibromyalgia
Effects of Laying on of Hands in Fibromyalgia
Fibromyalgia is conceptualized as non-inflammatory syndrome with manifestation in the musculoskeletal system associated with chronic generalized pain, fatigue, mood and sleep changes.
- Trial name
- NCT06195462
- Testing
- Laying on of hands with intention health (LHHI), Laying on of hands by spiritist passe, Control
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal do Triangulo Mineiro
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