Clinical trials: Myopathies
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Muscle Weakness
Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness
The goal of this trial was to determine if a mid-thoracic high velocity low amplitude spinal manipulation improves force output in those with unilateral hip adductor weakness.
- Trial name
- NCT06534931
- Testing
- High velocity low amplitude thoracic spine manipulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New England
Chronic Fatigue Syndrome
Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 Onset ME/CFS Versus Pre-Pandemic ME/CFS Patients
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex chronic illness impacting multiple body systems and characterized by activity-limiting fatigue and post exertional symptom exacerbation, affecting over 3.5…
- Trial name
- MECFS BBB (NCT07256795)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Musculoskeletal Pain, Disability Physical
Access to Chiropractic Care During the COVID-19 Healthcare Emergency in Spain
This is a pragmatic controlled clinical trial taking place in the first phase of COVID-19 lockdown re-opening in Spain. Patients of 52 chiropractic clinics were invited to participate in a pseudo-random order (one out of every…
- Conditions
- Musculoskeletal Pain, Disability Physical, Psychological Distress
- Trial name
- NCT04573361
- Testing
- Chiropractic care (one visit), Chiropractic care (more than one visit)
- Where
- Spain
- Volunteers
- 723 people
- Sponsor
- Real Centro Universitario Maria Cristina
Fibromyalgia, Dual Task
Dual Task in Female Patients With Fibromyalgia
The aim of our study is to examine the relationship between dual task and physical and psychosocial factors in female patients with fibromyalgia.
- Conditions
- Fibromyalgia, Dual Task, Physical Function, Psychosocial Problem
- Trial name
- NCT05210751
- Testing
- Physical and psychosocial assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Izmir Katip Celebi University
Duchenne Muscular Dystrophy
A Long-term Follow-up Study of Participants Who Received Delandistrogene Moxeparvovec (SRP-9001) in a Previous Clinical Study
The purpose of this study is to provide a single clinical study with a uniform approach to monitoring long-term safety and efficacy in participants who received delandistrogene moxeparvovec in a previous clinical study.
- Trial name
- EXPEDITION (NCT05967351)
- Testing
- delandistrogene moxeparvovec
- Where
- 38 sites in United States, Belgium and 7 more
- Volunteers
- 400 people
- Sponsor
- Sarepta Therapeutics, Inc.
Temporomandibular Disorders (TMD), Orofacial Pain
Telemonitoring for TMD-Related Pain
This prospective randomized clinical trial evaluates the effectiveness of a structured telemonitoring protocol as an adjunct to conservative management in patients with temporomandibular disorder (TMD)-related orofacial pain.
- Conditions
- Temporomandibular Disorders (TMD), Orofacial Pain, Myofacial Pain Syndromes, Myalgia of Mastication Muscle
- Trial name
- NCT07764770
- Testing
- Structured Telemonitoring, Conservative Management
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University Magna Graecia
DeQuervain's Tenosynovitis
Local Corticosteroid Injection Versus Open Surgical Release in De Quervain Tenosynovitis: A Single-Center Study
This quasi-experimental study compared pain outcomes following local corticosteroid injection (CSI) versus open surgical release in 100 patients with clinically confirmed De Quervain tenosynovitis unresponsive to conservative…
- Trial name
- NCT07683429
- Testing
- Triamcinolone acetonide with lidocaine, Open surgical release of first dorsal extensor compartment
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Rawalpindi Teaching Hospital, District Headquarter Hospital, Rawalpindi
Statin Intolerance
Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity
The purpose of this study is to gain insight into the side-effects of statin consumption, and assess the ability of epicatechin (a compound in dark chocolate) to counteract or reverse these changes.
- Trial name
- NCT02490527
- Testing
- Pure epicatechin capsules (50mg), Simvastatin (40mg)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Trigger Finger
Extracorporeal Shock Wave in the Treatment of Trigger Finger
Trigger finger (TF) is a condition that causes triggering, snapping, or locking on flexion of the involved finger, with a life- time risk between 2%-3% in the general population.
- Trial name
- NCT03928873
- Testing
- Low energy ESWT, High energy ESWT
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Fibromyalgia, Pain
Feasibility and Acceptability of Home-based Stretching Exercises in Fibromyalgia
The study aims to gather knowledge about the patient's acceptance of the intervention and testing procedures, assess the adherence to the intervention, estimate the recruitment rate, and inform the sample size calculation for a…
- Conditions
- Fibromyalgia, Pain, Quality of Life
- Trial name
- NCT06176053
- Testing
- Homebased stretching exercise and app supervision
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University College of Northern Denmark
Medial Tibial Stress Syndrome
Comparison of ESWT and Deep Tissue Massage in Individuals With Medial Tibial Stress Syndrome
This study, titled "Comparison of the Effectiveness of Extracorporeal Shock Wave Therapy and Deep Tissue Massage in Individuals with Medial Tibial Stress Syndrome (MTSS)," is designed as a prospective, randomized controlled trial…
- Trial name
- NCT07056426
- Testing
- Exercises, ESWT, Deep Tissue Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Ankara Yildirim Beyazıt University
Golfer's Elbow, Medial Epicondylitis
COMPARATIVE EFFECTS OF DRY NEEDLING AND NEURAL MOBILIZATION ON PAIN, STRENGTH AND RANGE OF MOTION IN PATIENTS WITH GOLFER'S ELBOW
This randomized clinical trial aims to compare the effectiveness of Dry Needling and Neural Mobilization in patients diagnosed with Golfer's Elbow (Medial Epicondylitis).
- Trial name
- DN-NM-GE (NCT07643740)
- Testing
- Dry needling, Neural mobilization
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- Green International University
Musculoskeletal Status, Muscle Weakness
Use of Jumping Mechanography as a Method to Assess Musculoskeletal Status in Older Adults
Decline in muscle function may increase risk of hip fracture and decrease quality of life. Different tests are currently used to measure muscle function but they do not work for all individuals.
- Trial name
- NCT00596089
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Muscle Damage
Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion
Purpose: To investigate the impact of milk protein ingestion on resistance exercise-induced muscle damage in untrained males and females.
- Trial name
- EIMD-MILK (NCT04986150)
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durham University
Fibromyalgia
High-definition Transcranial Electrical Stimulation for Fibromyalgia
Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct current or alternating current to change the excitability of the cerebral cortex.
- Trial name
- NCT04550598
- Testing
- HD-tCES
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Taipei Medical University
Trigger Finger
Endoscopic Trigger Finger Release
The purpose of this study is to compare recovery, scar, and patient satisfaction after retrograde endoscopic trigger finger release versus the standard open surgical treatment.
- Trial name
- NCT03883477
- Testing
- Endoscopic Release, Standard Open Release
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Fibromyalgia
Study of Milnacipran in Patients With Inadequate Response to Duloxetine for the Treatment of Fibromyalgia
The objective of this study is to evaluate the safety, tolerability and efficacy of milnacipran in patients with an inadequate response to duloxetine for the treatment of fibromyalgia.
- Trial name
- NCT01077375
- Testing
- Milnacipran
- Where
- 26 sites in United States
- Volunteers
- 107 people
- Sponsor
- Forest Laboratories
Fibromyalgia, Chronic Pain
Efficacy of Psychological Therapy in Chronic Pain and Fibromyalgia
Today, one of the most important challenges of the health system is the attitude towards chronic disorders. That implies changing from a health structure established for the treatment of acute diseases to a continued care system.
- Trial name
- DOLORTRATPSI (NCT03992612)
- Testing
- control group: usual medical care, MBPM- Mindfulness-Based Pain Management
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Duchenne Muscular Dystrophy (DMD)
Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy
This is a pharmacokinetic study (PK Study) to better understand empagliflozin dosing in pediatric Duchenne muscular dystrophy patients.
- Trial name
- CHERISH (NCT07172971)
- Testing
- SGLT-2 inhibitor, SGLT2 inhibitor
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University Medical Center
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