Clinical trials: Myopathies
Inflammatory Myopathy, Cardiac Disease
Adult Idiopathic Inflammatory Myopathy With Cardiac Injury
Adult patients with suspected or confirmed idiopathic inflammatory myopathy (IIM) will be recruited. Patients will be approached, consented, have baseline demographics, diagnostics and disease activity measures recorded, and…
- Trial name
- NCT05982041
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer, Quality of Life
Pilates and Dance to Breast Cancer Patients Undergoing Treatment
Breast cancer is one of the most common types of cancer in Brazil, and its treatment, namely surgery, chemotherapy, radiotherapy or hormone therapy, has consequences and side effects that significantly affect the quality of life…
- Conditions
- Breast Cancer, Quality of Life, Lymphedema, Fatigue
- Trial name
- NCT03194997
- Testing
- Dance, Pilates
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Laboratório de Pesquisa em Lazer e Atividade Física
Dupuytrens Contracture
Prospective Randomized Trial Between Needle Fasciotomy and Xiapex for Dupuytrens Contracture
The purpose of this study is to investigate whether percutaneous needle fasciotomy is as effective for treating Dupuytrens contracture as Xiapex.
- Trial name
- PNFvsxiapex (NCT02476461)
- Testing
- xiapex, percutaneous needle fasciotomy
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Chronic Fatigue Syndrome
Structural Problems in Brainstem and Cervical Spine Cord in ME/CFS
A case control study on patients with ME/CFS and healthy controls on prevalence of cervical obstructions, Cerebro spinal fluid (CSF) pressure and laboratory findings.
- Trial name
- NCT04403854
- Testing
- MRI, Spinal Tap
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bragee Clinics
Muscle Weakness, Muscle; Fatigue, Heart
The Impact of Beef on Muscle Fatigue in Older Adults
The goal of this controlled-feeding cross-over diet intervention is to compare a beef diet to a vegetarian diet on muscle fatigue in older adults.
- Conditions
- Muscle Weakness, Muscle; Fatigue, Heart, Older Adults
- Trial name
- NCT05860088
- Testing
- Beef Diet, Vegetarian Diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Duchenne Muscular Dystrophy
Phase 3 Trial of Pamrevlumab or Placebo With Systemic Corticosteroids in Participants With Non-ambulatory Duchenne Muscular Dystrophy (DMD)
To evaluate the efficacy and safety of pamrevlumab versus placebo in combination with systemic corticosteroids in participants with non-ambulatory Duchenne muscular dystrophy (age 12 years and older).
- Trial name
- LELANTOS-1 (NCT04371666)
- Testing
- Pamrevlumab, Corticosteroids
- Where
- 53 sites in United States, Australia and 12 more
- Volunteers
- 98 people
- Sponsor
- Kyntra Bio
Duchenne Muscular Dystrophy
A Study of Deflazacort (Emflaza®) in Participants With Duchenne Muscular Dystrophy (DMD)
The primary objective of this study is to evaluate the safety of a 0.9 milligrams per kilogram (mg/kg) and 0.45 mg/kg daily dose of deflazacort with a comparable natural history control group after 52 weeks of treatment in males…
- Trial name
- PTCEMF (NCT03642145)
- Testing
- Deflazacort
- Sponsor
- PTC Therapeutics
Myasthenia Gravis
Exploring Outcomes and Characteristics of Myasthenia Gravis 2
The goal of this prospective observational study is to create a network repository of clinical data and biological samples to help researchers learn more about myasthenia gravis.
- Trial name
- EXPLORE-MG2 (NCT06002945)
- Testing
- Blood sample
- Where
- 10 sites in United States
- Volunteers
- 311 people
- Sponsor
- Yale University
Amputation, Compartment Syndromes
Our Emergency Fasciotomy and Amputation Experiences
Earthquakes are natural disasters that threaten human life and cause loss of life and property in a very short time. In our country, where a large part of the population faces the risk of earthquakes, unfortunately, destructive…
- Conditions
- Amputation, Compartment Syndromes, Earthquake
- Trial name
- Earthquakes (NCT06764446)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Duchenne Muscular Dystrophy
AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)
RGX-202 is a gene therapy designed to deliver a transgene for a novel microdystrophin that includes functional elements of naturally-occurring dystrophin including the C-Terminal (CT) domain.
- Trial name
- NCT05693142
- Testing
- RGX-202
- Where
- 23 sites in United States, Canada
- Volunteers
- 65 people
- Sponsor
- REGENXBIO Inc.
Stretch, Plantar Fascia; Contracture
Effect of Stretching Exercises on Plantar Fascia
The plantar fascia (PF) extends over the calcaneal bone with a thin band corresponding to the calcaneal periosteum, continuing as the paratenon of the Achilles tendon.The triceps surae complex, serving as the main extensor and…
- Conditions
- Stretch, Plantar Fascia; Contracture, Fasciitis, Plantar
- Trial name
- NCT06370741
- Testing
- Stretching with/without device
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Okan University
Fibromyalgia, Pain, Chronic
Pain Severity in Fibromyalgia Syndrome
Fibromyalgia Syndrome (FMS) is a complex syndrome that mainly includes the musculoskeletal system and is characterized by many symptoms such as chronic widespread pain, fatigue and sleep disorders, cognitive dysfunctions…
- Trial name
- NCT05481086
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Kutahya Health Sciences University
Fibromyalgia
Effects of Diatermy in Patients With Fibromyalgia.
Diathermy is a non-invasive pain therapy based on the local application of high-frequency electromagnetic waves. This procedure produces deep heat promotes tissue repair and influences pain sensitivity.
- Trial name
- FIBDIAT (NCT06414369)
- Testing
- Diathermy, Simulated Diathermy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Camilo Jose Cela University
Fibromyalgia, Central Neuropathic Pain
Nitrous Oxide as Treatment for Fibromyalgia
The purpose of this study is to explore a potential role of nitrous oxide in treating pain associated with fibromyalgia.
- Trial name
- NCT05357066
- Testing
- Nitrous oxide gas for inhalation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Musculoskeletal Pain
Topical CBD for Musculoskeletal Pain
Rationale: CBD is commonly being used as an over-the-counter treatment for musculoskeletal pain; however, no clinical trial has been performed to establish efficacy of CBD in humans for musculoskeletal pain.
- Trial name
- NCT05170451
- Testing
- CBD, Control
- Where
- United States
- Sponsor
- University of Virginia
Spinal Cord Injury, Spasticity
Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury
Approximately 305,000 people live with a spinal cord injury (SCI) in the United States. Sixty percent of these individuals have tetraplegia, which can cause significant dysfunction of the arms and hands.
- Conditions
- Spinal Cord Injury, Spasticity, Shockwave Therapy
- Trial name
- NCT07501429
- Testing
- Focused extracorporeal shockwave therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
Well-Being, Psychological, Work Injury
Eastern Principles Acceptance and Commitment Therapy For Injury Prevention Among Nurses and Nursing Aides
This clinical trial will evaluate the effectivness of an Eastern Principles Acceptance and Commitment Therapy intervention (EPACT) relative to an estabished traditional Western-based Acceptance and Commitment Therapy intervention…
- Conditions
- Well-Being, Psychological, Work Injury, Musculoskeletal Pain, High Frequency Heart Rate Variability
- Trial name
- NCT06813495
- Testing
- Eastern Principles Acceptance and Commitment Therapy for Nurses and Nursing Aids (EPACT NNA), Acceptance and Commitment Therapy for Nurses and Nursing Aids (ACT NNA)
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Bowling Green State University
Giant Cell Tumors
Tenosynovial Giant Cell Tumors (TGCT) Observational Platform Project
TGCT is a rare disease that is difficult to manage, surgical resection is the primary treatment currently available. To date no disease registry exists and there is little data available detailing the management of patients with…
- Trial name
- TOP (NCT02948088)
- Where
- 15 sites in United States, Austria and 6 more
- Volunteers
- 183 people
- Sponsor
- Daiichi Sankyo
Epicondylitis, Tennis Elbow
Study of Sodium Hyaluronate to Provide Symptomatic Relief of Lateral Epicondylosis (Tennis Elbow)
A Randomized, Double-Blind, Placebo Controlled, Multi-Center Study of Sodium Hyaluronate to provide Symptomatic Relief of Lateral Epicondylosis (Tennis Elbow).
- Conditions
- Epicondylitis, Tennis Elbow, Epicondylosis
- Trial name
- NCT02861183
- Testing
- OVT (Sodium Hyaluronate), Saline
- Sponsor
- Anika Therapeutics, Inc.
Fibromyalgia, Fatigue
Functional Capacity Determinants in Fibromyalgia
Fibromyalgia is a chronic pain disorder characterized by widespread pain and multiple systemic symptoms that negatively affect functional capacity.
- Trial name
- NCT07318441
- Testing
- Assessment Only
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Democracy University
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