Clinical trials: Myopia; Refractive Error
Presbyopia
Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The purpose of this study is to evaluate the on-eye multifocal clinical performance of investigational LID233309 contact lenses and Oasys multifocal (MF) contact lenses in a daily wear dispensing trial.
- Trial name
- NCT06469242
- Testing
- Serafilcon A multifocal contact lenses, Senofilcon A multifocal contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
- Where
- 8 sites in United States
- Volunteers
- 106 people
- Sponsor
- Alcon Research
Myopia
Evaluation of Comfilcon A and Senofilcon A Lenses
Evaluation of Comfilcon A and Senofilcon A Lenses
- Trial name
- NCT01695369
- Testing
- Senofilcon A; Comfilcon A, Comfilcon A; Senofilcon A
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Astigmatism
Study of a Hand-held Device Plus Mobile App Versus Standard Eye Care Devices in Measuring Refractive Error of the Eye
Single-center, open-label, prospective study in healthy volunteers desiring refraction for correction of visual acuity to compare a handheld device supported by a mobile application with the phoropter and autorefractor.
- Trial name
- NCT03929588
- Testing
- Hand-held device supported by a mobile application, Phoropter, Autorefractor
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia
BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens
To determine if patients are unreactive to the lens care solution / Biofinity combination.
- Trial name
- NCT02196766
- Testing
- Bioclean First Care EX / comfilcon A, Aosept Clearcare / comfilcon A
- Where
- 3 sites in Japan
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Pain, Vision Nearsighted
Post Photorefractive Keratectomy (PRK) Use of an Eye Shield for Maintaining Vision and Mitigating Pain
The purpose of this research is to determine if an investigational thin shield over the cornea can safely and effectively reduce or eliminate pain following Post Photorefractive Keratectomy (PRK).
- Trial name
- Nexis-CS0032 (NCT01592643)
- Testing
- Eye Shield
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
Presbyopia, Near Vision
Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia
Phase 3 Efficacy Study to evaluate the Safety and Efficacy of LNZ100 \& LNZ101 for the Treatment of Presbyopia
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- CLARITY 2 (NCT05728944)
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 17 sites in United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia
A Dispensing Clinical of Fanfilcon A Lens Against Lotrafilcon B Lens Over 1 Month Wear Per Lens
This is a study to evaluate the performance of fanfilcon A lens when worn on a daily wear modality over approximately 1 month in comparison to the lotrafilcon B lens.
- Trial name
- NCT02716298
- Testing
- fanfilcon A, lotrafilcon B
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- CooperVision, Inc.
Presbyopia
A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With Presbyopia
The purpose of this study is to determine whether EV06 Ophthalmic Solution is safe and effective in improving distance corrected near vision in people who have presbyopia.
- Trial name
- NCT02516306
- Testing
- EV06 Ophthalmic Solution
- Where
- 4 sites in United States
- Volunteers
- 75 people
- Sponsor
- Encore Vision, Inc.
Myopia, Safety Issues
The Safety and Effectiveness of Breath-O Lenses
In Hong Kong, approximately 80% of children are myopic by the end of childhood. There is intense interest currently in the potential role of peripheral defocus as a clinical treatment to slow myopia progression.
- Trial name
- NCT03616600
- Testing
- Breath-O-Correct Lens
- Where
- Hong Kong
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Refractive Errors, Myopia
Clinical Assessment of a HYDRAGLYDE® Regimen
The purpose of this study is to evaluate worn AIR OPTIX® plus HYDRAGLYDE® (AOHG) lenses cleaned and disinfected with HYDRAGLYDE® containing lens solutions compared to each of the control habitual silicone hydrogel (SiHy) lenses…
- Conditions
- Refractive Errors, Myopia, Hypermetropia
- Trial name
- NCT03026257
- Testing
- Lotrafilcon B contact lenses with added wetting agent, Samfilcon A contact lenses, POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 323 people
- Sponsor
- Alcon, a Novartis Company
Refractive Error
AIR OPTIX® COLORS Registration Trial
The purpose of this study was to evaluate the subjective and objective performance and the physiological response to AIR OPTIX® COLORS soft contact lenses compared with AIR OPTIX® AQUA contact lenses in participants with normal…
- Trial name
- NCT01440322
- Testing
- Lotrafilcon B contact lens with color, Lotrafilcon B contact lens
- Volunteers
- 150 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses
The purpose of this study was to compare three CE-marked daily disposable contact lenses for tear film stability as measured by pre-lens non-invasive keratograph break up time (PL NIK-BUT).
- Conditions
- Myopia, Hyperopia, Refractive Error
- Trial name
- NCT01839318
- Testing
- Nelfilcon A contact lenses, Omafilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Myopia
A Comparison of Daily Disposable Contact Lenses.
This study seeks to evaluate the clinical performance of a new CE marked daily disposable contact lens that contains a wetting agent to a recently improved daily disposable contact lens.
- Trial name
- NCT00727558
- Testing
- nelfilcon A, narafilcon A
- Where
- 19 sites in United Kingdom
- Volunteers
- 248 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Comparison of Two Daily Disposable Contact Lenses
This study seeks to evaluate the clinical performance of a recently improved daily disposable contact lens to an established daily disposable contact lens that contains a wetting agent.
- Trial name
- NCT00600080
- Testing
- etafilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Clariti contact lenses.
- Trial name
- NCT03888482
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 154 people
- Sponsor
- Alcon Research
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT01787760
- Testing
- Test Soft Contact Lens B, Test Soft Contact Lens C, Active Comparator
- Where
- Hong Kong
- Volunteers
- 221 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Prospective Study of Two Daily Disposable Contact Lenses
The purpose of this study was to evaluate the performance of a novel silicone hydrogel contact lens, DAILIES TOTAL1® (DT1) compared to the standard hydrogel material in 1-DAY ACUVUE® MOIST® (1DAVM) contact lens in contact lens…
- Trial name
- NCT01636986
- Testing
- Delefilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Myopia
Feasibility of a New Silicone Hydrogel Lens
The objective of this study is to determine the product feasibility of the investigational contact lens (Test) when compared to the currently marketed Acuvue Oasys contact lens (Control) and the Air Optix Aqua contact lens…
- Trial name
- NCT01131130
- Testing
- Investigational contact lens, Acuvue Oasys Contact Lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Evaluating NeuroVision's Neural Vision Correction (NVC) Myopia Treatment
The purpose of the present study is to carry out a trial to evaluate the clinical efficacy of the NeuroVision Low Myopia Treatment. The specific questions to be answered are: 1.
- Trial name
- NCT00469612
- Testing
- NeuroVision's NVC treatment for Low Myopia
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Clinical Comparison of Silicone Hydrogel and HEMA-based Daily Disposable Contact Lenses
The purpose of this trial was to compare the performance of an investigational daily disposable contact lens to a commercially available daily disposable contact lens.
- Trial name
- NCT01362907
- Testing
- Delefilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 40 people
- Sponsor
- CIBA VISION