Clinical trials: Myopia
Cataract
Ocular Biometrics in a French Population
The investigators aimed to study ocular biometrics parameters and their association with age, gender and the prevalence of high myopia in a population of cataract surgery candidates in the South of France.
- Trial name
- NCT04992403
- Where
- France
- Volunteers
- 11,650 people
- Sponsor
- University Hospital, Montpellier
Myopia
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
Myopia, or shortsightedness, is a multifactorial disorder, governed by environmental and genetic factors. Myopia is the most common ocular disorder worldwide with an increasing prevalence over the past few decades and affecting…
- Trial name
- MODERATO (NCT07028827)
- Testing
- 0.05% atropine eye drops, 0.025% atropine eye drops
- Where
- 11 sites in Albania, Italy and 3 more
- Volunteers
- 234 people
- Sponsor
- Ocus Innovation Ireland Limited
Myopia, Astigmatism
Evaluation of Outcomes Following LASIK Surgery Using CustomVue
The aim of the study was to evaluate visual outcomes, contrast sensitivity, glare and induced high order aberrations induced by the new CustomVue software use for wavefront-guided LASIK.
- Conditions
- Myopia, Astigmatism, Myopic Astigmatism
- Trial name
- NCT00366769
- Testing
- Wavefront-guided LASIK using CustomVue platform
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Cataract, Astigmatism
Evaluation of Toric Intraocular Lens(IOL) Combined With Capsular Tension Ring(CTR) in Patients With Cataract Combined With High Myopia
The objective of this study is to evaluate the postoperative visual quality and IOL stability in patients with cataracts and high myopia who have undergone surgery using astigmatism-correcting IOLs in conjunction with tension…
- Conditions
- Cataract, Astigmatism, Intraocular Lens Rotation
- Trial name
- NCT06571773
- Testing
- intraoperative implantation of Capsular Tension Ring, none intraoperative implantation of CTR
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai 10th People's Hospital
Myopia
Comparison of Lens Fit and Lens Power of a New Contact Lens to Two Marketed Contact Lenses in a Population of Soft Contact Lens Wearers
The purpose of this study is to evaluate the comparability of lens fit and lens power of a new contact lens to the lens fit and lens power of two marketed lenses.
- Trial name
- NCT01244529
- Testing
- galy A Plus, seno A, galy A
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Refractive Error
Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia
Phase 3 study to evaluate the safety and effectiveness of LNZ100 \& LNZ101 for the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Error, Eye Diseases, Near Vision
- Trial name
- CLARITY 1 (NCT05656027)
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Brimonidine
- Where
- 25 sites in United States
- Volunteers
- 469 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Pseudophakia, Myopia
Treatment of Residual Refraction Errors 6 Months After Trifocal IOL Implantation With Relex-Smile
Successful treatment of residual refraction 6 months after IOL Implantation with Relex-Smile.
- Conditions
- Pseudophakia, Myopia, Hyperopia
- Trial name
- NCT04712318
- Testing
- Relex Smile, Relex smile with fresh corneal lenticule implantation
- Where
- Kosovo
- Volunteers
- 130 people
- Sponsor
- Eye Hospital Pristina Kosovo
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Myopia, Hyperopia
A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia
This clinical study has been planned to evaluate the safety and effectiveness of common treatment algorithms using 500 Hz laser repetition rate for the correction of Ammetropia and Presbyopia
- Conditions
- Myopia, Hyperopia, Presbyopia
- Trial name
- NCT02112968
- Testing
- Proscan, Zyoptix, Supracor
- Volunteers
- 97 people
- Sponsor
- Technolas Perfect Vision GmbH
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Keratoconus, High Myopia
Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging
The purpose of this study was to compare Scheimpflug corneal tomography findings in keratoconus and high myopic astigmatic eyes, as well as to establish the parameters distinguishing keratoconus from high myopic astigmatism.
- Trial name
- NCT06739018
- Testing
- pentacam scheimpflug tomography
- Where
- 2 sites in Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Myopia
Electronic Spectacles Versus Low Dose Atropine in Young Myopes
This is a bilateral, dispensing, masked, randomized clinical trial. Myopic children will be randomly assigned to one of the following: (1) Investigational clinical prototype (CP1) device without atropine, (2) Investigational CP1…
- Trial name
- NCT06034379
- Testing
- eSpectacle Clinical prototype (CP1) device, 0.01% atropine
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Refractive Errors, Cycloplegic Refraction
ML Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults
This study presents a machine learning model that predicts cycloplegic refraction in adults with myopia using standard non-cycloplegic eye measurements, aiming to reduce the need for cycloplegic drops while still identifying…
- Conditions
- Refractive Errors, Cycloplegic Refraction, Accommodation
- Trial name
- NCT07690813
- Testing
- Machine learning model for predicting cycloplegic refraction
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Myopia
Effects of Contact Lens Care Regimens on the Corneal Epithelium
The purpose of this study is to compare the performance of two different contact lens care solutions, specifically their affects on the front surface of the eye.
- Trial name
- NCT00349882
- Testing
- soft contact lens, Marketed multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Myopia
A Dispensing Comparison of a Test Daily 1 Day Lens Against a Control 1 Day Lens.
The purpose of this study is to compare the dispensing performance of somofilcon A test 1 day contact lens against somofilcon A control 1 day contact lens.
- Trial name
- NCT03951610
- Testing
- Test lens, Control lens
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- CooperVision, Inc.
Myopia
Spectacle Films Utilising S.T.O.P.® Technology for Slowing Down Myopia Progression in Children
There are two parts to this trial. First, to compare the rate of myopia progression of spectacle films using Spatio Temporal Optic Phase (S.T.O.P.®) technology that provide a dynamic optical cue against single vision spectacle…
- Trial name
- NCT06137560
- Testing
- Single vision spectacle lens, Single vision spectacle lens + S.T.O.P.® Kit 1, Single vision spectacle lens + S.T.O.P.® Kit 2
- Where
- 5 sites in China, India
- Volunteers
- 210 people
- Sponsor
- nthalmic Pty Ltd
Myopia, Hyperopia
DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study
The purpose of this study is to continuously assess the visual performance and safety of DAILIES TOTAL1 soft contact lenses in a real world setting and broader patient base through routine clinical practices.
- Conditions
- Myopia, Hyperopia, Presbyopia, Astigmatism
- Trial name
- NCT06483113
- Testing
- Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 192 people
- Sponsor
- Alcon Research
Myopia, Severe
Large Cohort of 1000 Patients With Severe Myopia
The prevalence of myopia and severe myopia are increasing and will affect 50% and 10% of the population respectively. Severe myopia exposes an increased risk of glaucoma, cataract, retinal detachment and myopic maculopathy, a…
- Trial name
- MyoCo1000 (NCT05849974)
- Testing
- Structural and fonctional phynotyping
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Myopia
Effectiveness and Safety of Repeated Low-Level Red-Light Therapy on Myopia Control Among Children and Adolescents
Myopia has become one of the leading causes of visual impairment globally and brings a heavy burden on the society. Therefore, preventing and controlling the progression of myopia has become an urgent public health issue that…
- Trial name
- NCT05871840
- Testing
- Repeated Low-Level Red-Light (RLRL) Therapy
- Volunteers
- 360 people
- Sponsor
- Shenzhen Hospital (Guangming), University of Chinese Academy of Sciences