Clinical trials: Myopia
Myopia
Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation
This study evaluates the safety and efficacy of a viscoelastic-free method for Implantable Collamer Lens(ICL) implantation to treat high myopia.
- Trial name
- NCT03059043
- Testing
- viscoelastic-free implantation system, standard viscoelastic-assisted Implantation system
- Where
- 5 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Myopia, Ear Acupressure Pellets
Effects of Auricular Point Pressing With Pellets in Children With Insufficient Hyperopia Reserve
This project aims to address the trend of early onset and high myopia among children in China by focusing on insufficient hyperopia reserve, a key early warning indicator for myopia.
- Conditions
- Myopia, Ear Acupressure Pellets, Hyperopia Reserve, Low-concentration Atropine Eye Drops
- Trial name
- NCT07475585
- Testing
- Ear acupoint pressure pellet intervention group, Atropine intervention group, Joint intervention Group
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Myopia
Base Curves of Bandage Contact Lenses and Their Effects on Post Trans-PRK Vision and Pain
The objective of this study was to investigate the impact of employing bandage contact lenses with a base curve of 8.4 mm versus 8.8 mm on visual recovery following Trans-PRK in patients characterized by steep corneas and high…
- Trial name
- NCT06393855
- Testing
- single-step Trans-PRK, Placing a bandage contact lens on the cornea, with an 8.4-mm base curve in right eye and one with an 8.8-mm base curve in the left eye., Placing a bandage contact lens on the cornea,A contact lens placed on the cornea, with an 8.8-mm base curve in right eye and one with an 8.4-mm base curve in the left eye.
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Dongyang People's Hospital
Retinal Detachment
Evaluation of Vitrectomy With ILM Peeling in Myopic Macular Hole With Only Posterior Retinal Detachment
Retinal detachment (RD) resulting from the macular hole (MH), also known as MH-induced RD (MHRD), most commonly occurs in eyes with high myopia and results in irreversible visual disorders.
- Trial name
- NCT06194760
- Testing
- Vitrectomy with ILM peeling
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Al-Azhar University
Cataract
Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction
The objective of this study is to compare the contrast sensitivity, high and low contrast visual acuity (VA), glare meter outcomes, and subject satisfaction with three different FDA-approved intraocular lenses (IOLs) designed to…
- Trial name
- NCT01225952
- Testing
- Crystalens AO, ReSTOR 3.0, AMO Tecnis Multifocal
- Where
- Philippines
- Volunteers
- 93 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Comparison of a Laser Keratome to a Mechanical Microkeratome
The purpose of this study was to evaluate the performance of the INTRALASE®, a laser keratome which creates a corneal flap, and compare it to a mechanical microkeratome (Amadeus™).
- Conditions
- Myopia, Astigmatism, Myopic Astigmatism
- Trial name
- NCT00366574
- Testing
- Amadeus Microkeratome, IntraLase
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Myopia
A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight
The objective of this study is to determine whether the remote monitoring of myopia patients with the EyeQue Insight (visual acuity test) can replace regularly scheduled follow-up visits.
- Trial name
- NCT04693260
- Testing
- Visual Acuity with a Hand-held Device Supported by Mobile App.
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia
Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye Drops
To assess the one-month ocular effects of nightly application of experimental BHVI2 and 0.02% atropine eye drops either alone or in combination, in children aged between 6 to 13 years old with myopia and randomized to use of…
- Trial name
- NCT03690414
- Testing
- Experimental BHVI2, Atropine sulfate 0.02% eye drops, Combination eye drops
- Where
- Vietnam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
Myopia
Evaluation of the Efficacy of Red Light in Adult Patients With High and Extreme Myopia
This study, led by Jie ying from the Ophthalmology Department of Beijing Tongren Hospital Affiliated to Capital Medical University, is a researcher-initiated clinical trial (IIT) designed to evaluate the therapeutic efficacy of…
- Trial name
- NCT07412678
- Testing
- Red light, Single vision spectacle lenses
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Beijing Tongren Hospital
Human Myopia Model
Clinical Research Plan for Human Myopia Models
Collect optical biological parameters, refractive index data, and other related parameters of myopia and refractive errors in children and adolescents, and establish an optical model of myopia in children and adolescents.
- Trial name
- NCT06185868
- Testing
- No intervention measures
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Robotrak Technologies Co., Ltd.
Cataract
A Dynamic Study of Pupil Diameter After Artificial Lens Implantation in Patients With High Myopia
Age-related cataract remains the leading cause of blindness in developing countries. And, with the aging of the population in these countries, the number of cataract patients will continue to grow.
- Trial name
- NCT06505434
- Testing
- Cataract surgery
- Volunteers
- 60 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram.
- Trial name
- NCT06282848
- Testing
- Atropine 0.05%, DIMS lens
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Mental Health
A Study of the Impact of Digital Intervention on Parents/primary Caregivers' Myopia Prevention and Control Health Literacy on Preschoolers' Myopia and Physical and Mental Health
The study is a Randomized controlled trial based on digital interventions, involving pre-school children and their parents or major caregivers.
- Conditions
- Myopia, Mental Health, Obesity
- Trial name
- NCT06620250
- Testing
- Digital Prevention and control of myopia
- Volunteers
- 882 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
High Myopia, Refractive Errors
Repeated Low-Level Red-Light Therapy for Shortening Axial Length
The purpose of this clinical trial is to confirm the incidence and magnitude of axial length shortening after RLRL therapy in Chinese high myopia children and teenagers.
- Conditions
- High Myopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05550740
- Testing
- RLRL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Corneal re-Epithelialization
A Study to Assess the Safety, Tolerability and Effect of Nexagon™ Applied to the Eye After PRK Laser Eye Surgery for Nearsightedness
Phase 1 randomized, prospective, double-masked, vehicle-controlled, dose-escalation study to evaluate the safety, tolerability and clinical effect of Nexagon™ in subjects following bilateral PRK for the correction of mild to…
- Trial name
- NCT00654550
- Testing
- Nexagon™ or Nexagon™ vehicle
- Where
- New Zealand
- Volunteers
- 24 people
- Sponsor
- OcuNexus Therapeutics, Inc.
Myopia, Progressive
A Unified Index to Predict the Success Probability of Myopia Control
Orthokeratology lenses (OK-lens) and multifocal contact lenses (MFCL) are optical devices designed to slow down the progression of myopia. Both treatments a long-term commitment from doctors and patients.
- Trial name
- NCT05773118
- Testing
- orthokeratology lens, multifocal soft contact lens, Single vision spectacles
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Myopia, Orthokeratology
Effectiveness of Myopia Control by Breath-O Correct Orthokeratology Lenses
This is a 24-month longitudinal randomized controlled trial aiming to evaluate the effectiveness of myopia control by Breath-O correct orthokeratology lenses in different myopia progression groups classified according to their…
- Trial name
- NCT03919396
- Testing
- Breath-O orthokeratology lenses
- Where
- Hong Kong
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Prevention of Myopia of Prematurity by Calcium Supplementation
The purpose of this study is to determine if supplementation of calcium by the enteral route (gut feeding) to extremely low birth weight infants will lead to less myopia (nearsightedness) at 6-12 months postnatal age.
- Trial name
- NCT00892476
- Testing
- Calcium Supplementation, Standard of Care
- Volunteers
- 99 people
- Sponsor
- University of Alabama at Birmingham
Myopia
Effects of Contact Lens Care Regimens on the Corneal Epithelium
The purpose of this study is to compare the performance of two different contact lens care solutions, specifically their affects on the front surface of the eye.
- Trial name
- NCT00349882
- Testing
- soft contact lens, Marketed multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Myopia, Keratoconus
Assessment of Corneal Biomechanical Properties Using Corvis ST and ECD Following LASIK, PRK, CXL, Veriflex IOL and Implantable Collamer Lens
To evaluate corneal biomechanical changes using the Corvis ST and ECD in patients who have under-gone LASIK, PRK, corneal cross-linking (CXL), Veriflex IOL and ICL.
- Conditions
- Myopia, Keratoconus, Refractive Surgery
- Trial name
- NCT06818461
- Testing
- Corvis St Before and after lasik, PRK, CXL, Veriflex IOL and ICL
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University