Clinical trials: Myopia Progression
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Myopia
Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center
This randomized controlled trial aims to evaluate the efficacy and safety of low-dose topical atropine sulphate (0.05%), a non-selective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in…
- Trial name
- NCT07164092
- Testing
- Atropine 0.05% Eye drops
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Myopia
Red Light Intervention on Myopic Progression
To explore the effectiveness of using repeated low-level red-light therapy to slow myopia progression.
- Trial name
- NCT05203432
- Testing
- Red Light Intervention, Atropine
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
High Myopia, Posterior Scleral Reinforcement
Efficacy and Safety of Posterior Scleral Reinforcement on Controlling Myopia in Adults With High Myopia
This study will evaluate the efficacy and safety of posterior scleral reinforcement on controlling myopia progression, including change in refraction, axial elongation as well as sight-threatening complications, in adults with…
- Conditions
- High Myopia, Posterior Scleral Reinforcement, Adults, Axial Elongation
- Trial name
- NCT03381079
- Testing
- Posterior scleral reinforcement
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Refractive Errors
Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities
Chinese children are some of the most short-sighted in the world, but only one in five children in poor areas who needs glasses has them.
- Trial name
- SWISH (NCT04077086)
- Testing
- Spectacles
- Where
- 3 sites in China, United Kingdom
- Volunteers
- 10,000 people
- Sponsor
- Queen's University, Belfast
Myopia, Myopia Progression
Mobility Performance in Daily Activities Among Children Wearing Spectacle Lenses
The aim of this study is evaluate and compare the mobility performance of children in daily activities while wearing single vision spectacle lenses (control) versus myopia control spectacle lenses (test).
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- NCT07229352
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia, Myopia, Progressive
Can Distance Center and Near Center Multifocal Contact Lenses Control Myopia Progression in Children?
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequency and severity of various ocular pathologies.
- Trial name
- ADPADP (NCT03519490)
- Testing
- Hybrid Contact Lens
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas A. Aller, OD
Myopia
The Effect of +3.00ADD on Myopia Progression in Chinese Children
The purpose of this study is to evaluate the effect of +3.00ADD vs single vision spectacle on the progression of myopia in children.
- Trial name
- NCT03242226
- Testing
- two spectacles, single vision spectacles
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Progressive, Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression
This is a monocenter, randomized, controlled, parallel-group, double-masked clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation at baseline compared to a…
- Trial name
- NCT05331378
- Testing
- Test myopia control lenses, Single vision lenses
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Myopia Control With Simultaneous Vision Approach
To determine if the 'Defocus Incorporated Soft Contact' (DISC) lens slows myopia progression in Hong Kong schoolchildren using simultaneous vision approach.
- Trial name
- NCT00919334
- Testing
- Defocus Incorporated Soft Contact (DISC) lens
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Myopia Progression Trial With Novel Myopia Control Design Spectacle Lenses
This is a mono-center, randomized, double-masked, cross-over study to evaluate rate of myopia progression with novel designed myopia control lens (test) compared to SVL (control).
- Trial name
- NCT04048148
- Testing
- Novel designed myopia control spectacle lenses
- Where
- Vietnam
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision Institute
Myopia
Myopia Control With a Innovative Spectacle Lens
The purpose of this study is to demonstrate that the test spectacle lens is safe and effective in slowing myopia progression in children.
- Trial name
- NCT05174780
- Testing
- innovative myopia control spectacle lens, Single vision spectacle lens
- Where
- 9 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Refractive Error - Myopia
Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression
To explore the minimum power and frequency of Repeated Low-level Red-light (RLRL) to control myopia progression in low-myopic children aged 8-10 years, and the rebound effect of low-myopic children after discontinuation of RLRL…
- Conditions
- Myopia, Refractive Error - Myopia, Choroidal Thickness, Retina
- Trial name
- NCT06717048
- Testing
- Repeated Low-level Red-light, Red LED
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT01787760
- Testing
- Test Soft Contact Lens B, Test Soft Contact Lens C, Active Comparator
- Where
- Hong Kong
- Volunteers
- 221 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Safety and Efficacy Study of 0.5%, 0.1% & 0.01% Atropine Treatment to Both Eyes In Treatment of Myopia In Children
The purpose of this study is to find an optimal dose of atropine for preventing the rapid progression of myopia in children by comparing the efficacy, safety and functional impact of binocular treatment with 0.5%, 0.1% and 0.01%…
- Trial name
- NCT00371124
- Testing
- Atropine Eye drops
- Where
- Singapore
- Volunteers
- 400 people
- Sponsor
- Singapore National Eye Centre
Myopia, Esophoria
Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
The purpose of this study is to determine whether bifocal soft contact lenses are effective in controlling the progression of myopia in children and adolescents that exhibit a tendency to excessively cross their eyes while…
- Conditions
- Myopia, Esophoria, Fixation Disparity
- Trial name
- NCT00214487
- Testing
- Bifocal Contact Lenses
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Intermittent Exotropia, Myopia Overcorrection
Overminus Lens Therapy in Intermittent
In this prospective study, entitled "The Long-Term Efficacy of Overminus Lens Therapy in Intermittent Exotropia",the investigators examined the long-term impact of overminus lenses on the management of intermittent exotropia…
- Conditions
- Intermittent Exotropia, Myopia Overcorrection, Over-minus Therapy, Myopia Progression
- Trial name
- NCT03952702
- Testing
- Myopic overcorrection
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ege University
Myopia Progression
Effectiveness of Orthokeratology in Decreasing Myopic Progression in a Young Adult Population Enrolled in a Professional Optometric Curriculum
The high prevalence of myopia - especially in Asian countries - is well documented, as are the sight-threatening complications of high or degenerative myopia.
- Trial name
- NCT02623543
- Testing
- OrthoK
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Illinois College of Optometry
Myopia
Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United Kingdom
Short-sightedness, also called myopia, makes objects in the distance, such as the television, look blurred. This is caused by the eye growing too long, something that usually happens while children are also getting taller.
- Trial name
- CHAMP-UK (NCT03690089)
- Testing
- Atropine Sulfate
- Where
- 4 sites in United Kingdom
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Myopia
Effectiveness of DIMS Spectacle as a Function of the Age
Purpose: To evaluate the effectiveness of Defocus Incorporated Multiple Segments (DIMS) in slowing myopia progression as a function of age in pediatric patients.
- Trial name
- NCT06556849
- Testing
- Defocus Incorporated Multiple Segments (DIMS)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Luca Buzzonetti