Clinical trials: Myopic Children
Myopia
Retardation of Myopia in Orthokeratology
The primary aim of this study is to evaluate and compare the eyeball elongation in children wearing orthokeratology lenses and single-vision spectacles.
- Trial name
- ROMIO (NCT00962208)
- Testing
- orthokeratology lenses, single-vision spectacle lenses
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
CHAMP: Study of NVK-002 in Children With Myopia
Stage 1: To evaluate the safety and efficacy of 2 concentrations of NVK-002 compared to Vehicle (placebo) for slowing the progression of myopia in children over a 3 year treatment period.
- Trial name
- NCT03350620
- Testing
- NVK-002 Concentration 1, NVK-002 Concentration 2
- Where
- 26 sites in United States, Hungary and 4 more
- Volunteers
- 670 people
- Sponsor
- Vyluma, Inc.
Refractive Errors
Bifocal & Atropine in Myopia (BAM) Study
This study will test whether the combined treatment of 0.01% atropine and soft bifocal contact lens wear produces slower myopia progression and axial elongation compared to soft bifocal contact lenses alone in children ages 7 to…
- Trial name
- BAM (NCT03312257)
- Testing
- Multifocal D +2.50 add & 0.01% atropine
- Volunteers
- 49 people
- Sponsor
- Jenny Jones
Myopia, Esophoria
Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
The purpose of this study is to determine whether bifocal soft contact lenses are effective in controlling the progression of myopia in children and adolescents that exhibit a tendency to excessively cross their eyes while…
- Conditions
- Myopia, Esophoria, Fixation Disparity
- Trial name
- NCT00214487
- Testing
- Bifocal Contact Lenses
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopia
Low-dose Atropine for the Prevention of Myopia Progression in Danish Children
Myopia (nearsightedness) is increasing in prevalence throughout the world. It is associated with a risk of potentially blinding complications such as retinal detachment and myopic maculopathy.
- Trial name
- APP (NCT03911271)
- Testing
- 0.1% atropine and 0.01% atropine, 0.01% atropine, 0.9% Sodium-chloride
- Where
- 3 sites in Denmark
- Volunteers
- 97 people
- Sponsor
- Line Kessel
Myopia
Discontinuation of Lens Wear in New Ortho-k Children (DOEE2)
This study aims at investigating the efficacy of myopic control using ortho-k in younger and older children.
- Trial name
- DOEE2 (NCT01236755)
- Testing
- single-vision glasses, ortho-k lenses
- Where
- China
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Discontinuation of Orthokeratology on Eyeball Elongation in Myopic Children
The primary aim of this study is to compare eyeball elongation in existing ortho-k subjects who stop the treatment with subjects who continue ortho-k lens wear and control subjects wearing single-vision glasses.
- Trial name
- DOEE1 (NCT01236742)
- Testing
- ortho-k lenses, single-vision glasses
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Correction of Myopia Evaluation Trial 2
The purpose of the study is to determine if progressive addition lenses (PALs) versus single vision lenses (SVLs) slow the progression of low myopia in children with poor accommodative responses (i.e., large accommodative lags)…
- Trial name
- COMET2 (NCT00320593)
- Testing
- Progressive Addition Lenses (PALs), Single Vision Lenses (SVLs)
- Where
- 8 sites in United States
- Volunteers
- 118 people
- Sponsor
- Jaeb Center for Health Research
Nearsightedness, Near Sightedness
The Safety and Efficacy of SYD-101 in Children With Myopia
Myopia, or nearsightedness, is the most common eye disorder, often affecting more than 40% of adults in Europe, Asia and the USA.
- Conditions
- Nearsightedness, Near Sightedness, Near-sightedness
- Trial name
- STAR (NCT03918915)
- Testing
- SYD-101 0.01%, SYD-101 0.03%, Vehicle
- Where
- 47 sites in United States, Austria and 1 more
- Volunteers
- 852 people
- Sponsor
- Sydnexis, Inc.
Refractive Errors
Bifocal Lenses In Nearsighted Kids
This study will evaluate the use of two different bifocal contact lens add powers to prevent further nearsighted progression in children ages 7 to 11 years old.
- Trial name
- BLINK (NCT02255474)
- Testing
- Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Ohio State University