Clinical trials: NERVES
Inferior Alveolar Nerve, Mandibular Nerve Blocks
Use of CBCT to Improve Inferior Alveolar Nerve Block Success
The study looks to compare the success rate of lower jaw anesthesia injection (inferior alveolar nerve) that is guided by pre-treatment 3D dental scan (CBCT) versus standard injection technique.
- Trial name
- NCT05406895
- Testing
- 2% Lidocaine with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Intertransverse Process Block, Thoracic Nerve Block
A Novel Intertransverse Plane Block: a Magnetic Resonance Imaging and Volunteer Study
Intertransverse process block (ITPB) is a thoracic nerve block technique where the LA is injected into the thoracic "intertransverse tissue complex" posterior to the superior costotransverse ligament (SCTL).
- Conditions
- Intertransverse Process Block, Thoracic Nerve Block, Thoracic Paravertebral Block
- Trial name
- NCT05538884
- Testing
- Intertransverse process block
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Inferior Alveolar Nerve Injuries, Impacted Third Molar Tooth
The Impact of 3D-CBCT Imaging on Nerve Injuries During Wisdom Tooth Surgery
The investigators aim to investigate if the additional information available from a 3D scan of the wisdom tooth can reduce the risk of nerve injury during wisdom tooth surgery compared to conventional 2D images.
- Trial name
- IMPACTION (NCT06261853)
- Testing
- 3D-CBCT, 2D-OPG
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,292 people
- Sponsor
- University of Aberdeen
Accessory Nerve Injuries, Physical Therapy
Assessing the Implementation of Myofascial Techniques in Patients With Accessory Nerve Damage After Oncologic Treatment
The majority of head and neck cancers develop locally and regionally. Therefore, to reduce the risk of metastasis, 90% of surgeries performed in the head and neck area include the removal of regional lymph nodes and delivery of…
- Trial name
- PHYSIOACCESS (NCT06397742)
- Testing
- Physical activity, Physical therapy - myofascial techniques
- Where
- Poland
- Volunteers
- 57 people
- Sponsor
- The Greater Poland Cancer Centre
Acute Post-operative Pain, Nerve Block
Comparison of Analgesia Efficacy of Transversus Abdominis Plane Block and Posterior Approach Quadratus Lumborum Block
Prostate cancer is the second most common cancer and the fifth in cancer-related deaths. Open radical retropubic prostatectomy is the most common surgical treatment for localized prostate cancer.
- Conditions
- Acute Post-operative Pain, Nerve Block, Prostate Cancer
- Trial name
- NCT06075498
- Testing
- transversus abdominis plane block,
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Muğla Sıtkı Koçman University
Vestibular Schwannoma, Acoustic Neuroma
Auditory Nerve Test System During Vestibular Schwannoma Resection
The Auditory Nerve Test System (ANTS) is a novel device that stimulates the auditory nerve much like a cochlear implant. The purpose of this study is to demonstrate feasibility of the ANTS during translabyrinthine surgery for…
- Conditions
- Vestibular Schwannoma, Acoustic Neuroma, Sensorineural Hearing Loss, Asymmetric Sensorineural Hearing Loss
- Trial name
- ANTS (NCT04241679)
- Testing
- Auditory Nerve Test System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Ischemic Stroke, Vagus Nerve Stimulation
Effect Of Robotic Rehabilitation And Vagus Nerve Stimulation In Ischemia Stroke Patients
This study was conducted in patients with ischemic stroke; This study was conducted to examine the effect of robotic rehabilitation and transcutaneous auricular vagal nerve stimulation applied in addition to robotic…
- Conditions
- Ischemic Stroke, Vagus Nerve Stimulation, Robotic Rehabilitation, Autonomic Nervous System
- Trial name
- ERRVNS (NCT06381089)
- Testing
- Robotic Rehabilitation, Transcutaneous Auricular Vagal Nerve Stimulation
- Volunteers
- 40 people
- Sponsor
- SEFA HAKTAN HATIK
Parkinson Disease
Progression Follow up of the First-degree Relatives of Patients With REM Sleep Behavior Disorder
REM sleep behavior disorder is a novel and distinct parasomnia characterized by recurrent dream enactment behaviors (DEBs) and polysomnographic features of REM sleep without atonia (RSWA), with typical onset age at early 60's.
- Trial name
- NCT05353959
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Ultrasound Imaging of Anatomical Structures, Nerve Block
Nerve and Plane Block Data Collection Study for the Development of Artificial Intelligence-assisted Software
The primary objective of this observational study is to acquire ultrasound images (raw data) from nerve and plane block regions to develop artificial intelligence-guided nerve block software (Nerveblox).
- Trial name
- NCT06375603
- Testing
- Ultrasound scans
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Smart Alfa Teknoloji San. ve Tic. A.S.
New Nerve Conduction Protocol for Pectoral Nerve
Electrodiagnostic Approach for Pectoral Nerve Conduction Studies
Anatomical studies have challenged traditional perceptions of the pectoral nerve structure, revealing a network of three branches rather than the previously accepted medial and lateral branches.
- Trial name
- NCT06369376
- Testing
- New nerve conduction protocol
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Dorsal Scapular Nerve Entrapment
Dorsal Scapular Nerve Injection Combined With Muscle Needle Release
Ultrasound-guided perineural injection (PIT) of 5% dextrose (D5W) hydrodissection has been widely used in the treatment of peripheral entrapment neuropathies.
- Trial name
- NCT06329960
- Testing
- Ultrasound-guided injection combined with needle release
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Nerve Condition, Health, Subjective
Evaluation of Nerve Conduction Study
the investigators study different modality to obtain nerve evoked reponses. They use different parameters of acquisition and stimulation and they compare amplitude and latency of nerve conduction response
- Trial name
- SPEMG (NCT06367478)
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring
Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes.
- Conditions
- ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter, Intracranial Hypertension
- Trial name
- NCT06367868
- Testing
- After 5 ml CSF Drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa
Nerve Block
USG Block of Cutaneous Nerves of the Arm
For superficial surgery of anteromedial and posteromedial surfaces of the upper arm, the medial brachial cutaneous nerve (MBCN) and the intercostobrachial nerve (ICBN) must be selectively blocked, in addition to an axillary…
- Trial name
- NCT03928574
- Testing
- Ultrasound-Guided Plane Block, Conventional Block
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Nerve Block
US-Guided Superficial Cervical Plexus Block
This retrospective observational study compare ultrasound-guided plane and landmark-based superficial cervical plexus block
- Trial name
- NCT03933566
- Testing
- Ultrasound-Guided Superficial Cervical Plexus Block, Landmark-Based Superficial Cervical Plexus Block
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Brain and Central Nervous System Tumors, Intraocular Melanoma
Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer
RATIONALE: Radiolabeled monoclonal antibodies, such as iodine I 131 monoclonal antibody 3F8, can find tumor cells and carry tumor-killing substances to them without harming normal cells.
- Conditions
- Brain and Central Nervous System Tumors, Intraocular Melanoma, Lung Cancer, Melanoma (Skin)
- Trial name
- NCT00445965
- Testing
- DNA analysis, immunologic technique, pharmacological study
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Neurofibromatosis Type 1, Plexiform Neurofibroma
Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours
Phase I and II study of the MEK inhibitor Selumetinib given twice daily on 5 out of 7 days in children with NF1 and inoperable plexiform neurofibromas or progressive/relapsed optic pathway gliomas.
- Conditions
- Neurofibromatosis Type 1, Plexiform Neurofibroma, Optic Nerve Glioma
- Trial name
- INSPECT (NCT03326388)
- Testing
- Selumetinib
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Stress, Psychological, Sleep
Stress and Sleep Study
This between-subject, longitudinal pilot study in healthy college students aims to explore the acceptability and preliminary outcomes of two novel and complementary interventions that may improve stress and sleep: transcutaneous…
- Conditions
- Stress, Psychological, Sleep, Transcutaneous Electric Nerve Stimulation, Vagus Nerve Stimulation
- Trial name
- NCT05218109
- Testing
- tVNS, Mindfulness, Number Puzzle
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Florida
Esophageal Neoplasm, Anastomotic Leak
Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation
Analyze the correlation between the conformity of the anatomy (based on endoscopic examination) and postoperative anastomotic fistula and anastomotic stenosis; establish an anastomotic classification; and construct a predictive…
- Conditions
- Esophageal Neoplasm, Anastomotic Leak, Recurrent Laryngeal Nerve Injuries, Anastomotic Stenosis
- Trial name
- NCT06348381
- Testing
- No intervention
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shanghai Chest Hospital
Nerve Block, Cleft Palate
Maxillary Nerve Blocks in Children - An MRI Study of the Suprazygomatic Approach
Ultrasound-guided suprazygomatic maxillary nerve block (SMNB) will be performed in paediatric patients with or without the aid of ultrasound guidance.
- Conditions
- Nerve Block, Cleft Palate, Analgesia
- Trial name
- NCT05778903
- Testing
- Nerve block
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital