Clinical trials: NEURON SPECIFIC ENOLASE
Cervical Compression Myelopathy, Ischemia
Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery
The purpose of this study is to assess whether a large clinical trial testing the effect of RIPC on neurologic outcome in patients undergoing elective cervical decompression surge is warranted.
- Conditions
- Cervical Compression Myelopathy, Ischemia, Reperfusion Injury, Spinal Cord Injury
- Trial name
- NCT00778323
- Testing
- limb remote ischemic preconditioning (LRIPC)
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Xijing Hospital
Peri-operative Injury, Newborn, Infant, Disease
Cerebral Oxymetry and Neuronal Markers in Newborns and Infants Undergoing Surgery
The purpose of this study is to assess whether peri-operative period in neonates and infants is associated with an increase in blood biomarkers, specific for neuronal injury, and to correlate them with clinical variables and…
- Trial name
- NEMARKO (NCT02423369)
- Testing
- Cerebral near infrared spectroscopy, S-100B protein in serum, NSE protein in serum
- Where
- Lithuania
- Volunteers
- 49 people
- Sponsor
- Lithuanian University of Health Sciences
Traumatic Brain Injury
Safety of Darbepoetin Alfa Treatment in Patients With Severe Traumatic Brain Injury
The purpose of this study is to see if the treatment of severely brain injured patients with darbepoetin (a long acting form of erythropoietin) will be safe, and will reduce brain damage by decreasing harmful levels of chemicals…
- Trial name
- NCT00375869
- Testing
- Darbeopoetin
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Royal Alexandra Hospital
Out of Hospital Cardiac Arrest, Brain Injury
Therapeutic Hypothermia and eArly Waking
Unconscious survivors of cardiac arrest who are treated with intravenous therapeutic hypothermia for 24 hours will be assessed after 12 hours for appropriateness to be woken early and extubated whilst continuing to receive…
- Trial name
- THAW (NCT03065946)
- Testing
- Early wakening
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Generalized Epilepsy
Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy
Epilepsy is one of the most common and frequently encountered neurological conditions that impose a huge burden on the healthcare systems.
- Trial name
- NCT03590197
- Testing
- Melatonin 3 mg
- Where
- India
- Volunteers
- 104 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Seizures, Focal
Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures
The present study has been planned to assess the level of serum neuron-specific enolase (NSE) in focal seizures and its changes after antiepileptic therapy.
- Trial name
- NCT02705768
- Testing
- Carbamazepine, Oxcarbazepine
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Cardiac Arrest, Hypothermia
Neuron Specific Enolase (NSE) as Outcome Parameter of Cooling Therapy After Survived Sudden Cardiac Death
Sudden cardiac death remains one of the major leading causes of death. Therapeutic hypothermia is a validated standard procedure to avoid or minimize cognitive deficits after cardiac arrest.
- Trial name
- NCT01102153
- Testing
- Coolgard, ArcticSun
- Where
- 2 sites in Germany
- Volunteers
- 108 people
- Sponsor
- University of Leipzig
Kidney Transplant; Complications, Neurologic Manifestations
Evaluation of s100β, NSE and GFAP Levels in Renal Transplantation
Uremic encephalopathy is an organic brain disorder may be frequently seen in patients with acute or chronic renal failure. Certain neurological symptoms can be found under clinical glomerular filtration rate of 15 ml/minutes.
- Conditions
- Kidney Transplant; Complications, Neurologic Manifestations, Uremic Encephalopathy
- Trial name
- NCT04042272
- Testing
- S100β, Neuron specific enolase (NSE) and Glial fibrillary acidic protein (GFAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Carcinoma, Non-Small-Cell Lung
NSE/Alb as a Prognostic Biomarker for Lung Cancer
The incidence and mortality rate of lung cancer is the highest in the world. Current studies have found that tumor markers, inflammatory or nutritional indicators have a good predictive value for the prognosis of patients with…
- Trial name
- NARPBLC (NCT03724604)
- Testing
- Neuron-Specific Enolase to Albumin Ratio
- Where
- China
- Volunteers
- 202 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Spinal Injury
Neuromarker S-100B as Diagnostic Tool
The hypothesis of this study is to find evidence if there is an influence of spine surgery on the serum levels of two proteins secreted from neuronal cells.
- Trial name
- SpineSurgery (NCT01840397)
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna