Clinical trials: NGAL
Urinary Stone, Renal Injury
Urinary NGAL and KIM-1 After ESWL
The goal of this prospective observational study is to evaluate the effect of different time intervals between extracorporeal shock wave lithotripsy (ESWL) sessions on renal injury using urinary biomarkers in patients with…
- Trial name
- NCT07341269
- Testing
- No Interventions, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Kidney Failure, Acute, Renal Insufficiency
Examining New Diagnostic Tests for Acute Kidney Injury After Heart Surgery
People who undergo coronary artery bypass grafting (CABG) or heart valve surgery may experience acute kidney injury (AKI) after their surgery.
- Trial name
- NCT00774137
- Where
- 8 sites in United States, Canada
- Volunteers
- 1,550 people
- Sponsor
- Yale University
Obesity
Anthropometric Measures and Anti-inflammatory Markers by a PUFAs Enriched Diet
In this work, the investigators report the effects of consume of 15g walnuts and 15g almonds for 8 week on weight, waist and hip circumferences, body mass index, fat mass, serum LDL-cholesterol adiponectin, lipocalin-2…
- Trial name
- NCT03211754
- Testing
- walnuts and almonds
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Systemic Inflammatory Response Syndrome, Oliguria
Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study
The investigators will determine the feasibility, safety and efficacy of intravenous sodium bicarbonate in reducing progression to overt acute renal failure in patients with the systemic inflammatory response syndrome, and low…
- Conditions
- Systemic Inflammatory Response Syndrome, Oliguria, Renal Impairment
- Trial name
- BLISS (NCT00706771)
- Testing
- Sodium bicarbonate, Sodium chloride
- Where
- 2 sites in Australia
- Volunteers
- 70 people
- Sponsor
- Austin Health
Rhabdomyolysis, Acute Kidney Failure
Plasma Neutrophil Gelatinase Associated Lipocalin Levels During Emergency Management of Rhabdomyolysis
This research project consists of a prospective diagnostic study conducted on patients with clinical suspicion of rhabdomyolysis admitted to the emergency rooms of the University Hospitals of Nimes, Montpellier, Paris, Nice and…
- Trial name
- NCT01544231
- Testing
- Plasma NGAL level
- Where
- 5 sites in France
- Volunteers
- 197 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Kidney Injury, Congenital Cardiac Disorders
Urine Biomarkers to Predict Acute Kidney Injury After Pediatric Cardiac Surgery
The goal of this prospective cohort study is to evaluate, in pediatric patients after cardiac surgery, the predicting capability of biomarkers for acute kidney injury.
- Trial name
- NCT05637424
- Volunteers
- 101 people
- Sponsor
- University Ghent
the Patients With Partial Nephrectomy
Assessment of Acute Renal Injury During Partial Nephrectomy Using Neutrophil Gelatinase-associated Lipocalin (NGAL): Prospective Comparative Study Between Open, Video-assisted Minilaparotomy, Laparoscopic, and Robotic-assisted Laparoscopic Surgery
Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of acute kidney injury.
- Trial name
- NCT01891032
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Yonsei University
Moderate to Severe Ulcerative Colitis
Study on Variation of Serum and Fecal Biomarkers After Treatment to Predict Mucosal Healing in Patients With Ulcerative Colitis
Mucosal healing is recognized hitherto as the best therapeutic endpoint in patients with Ulcerative Colitis (UC) but its use in daily practice is limited by the low acceptability of repeated colonoscopies.
- Trial name
- MIROIR (NCT07653750)
- Testing
- Serum and fecal measurements
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Kidney Disease-Mineral and Bone Disorder
Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients
The goal of this observational study or clinical trial is to learn about the effect of neutrophil gelatinase-associated lipocalin (NGAL) on vascular calcification in maintenance hemodialysis patients with secondary…
- Trial name
- NGAL (NCT05720273)
- Testing
- palicalcitol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiaoyan Jia
Acute Kidney Injury
Effect of CVVH on NGAL in Septic AKI
The plasma level of neutrophil gelatinase-associated lipocalin (NGAL) in critically ill patients with AKI is not affected by continuous venovenous hemofiltration (CVVH).
- Trial name
- NCT02536027
- Testing
- continuous venovenous hemofiltration
- Volunteers
- 30 people
- Sponsor
- First People's Hospital of Chenzhou
Urinary Tract Infection Complicated, Kidney Stones
Resistance Characteristics and Development of Diagnostic Model for Postoperative UTI in Patients With Kidney Stones
The combined detection of HBP, ADPN, NGAL, and hs-CRP enables the construction of a highly efficient diagnostic model, offering a novel strategy for early infection identification and risk stratification after surgery.
- Conditions
- Urinary Tract Infection Complicated, Kidney Stones, Antimicrobial Resistance
- Trial name
- NCT06946667
- Testing
- the UTI group, the Non-UTI group
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Xingxin Jiang
Acute Renal Failure, Sepsis
Angiotensin in Septic Kidney Injury Trial
The purpose of this study is to determine the effect of a systemic infusion of angiotensin II on haemodynamics and urine output in critically ill patients with severe sepsis/septic shock and acute renal failure.
- Conditions
- Acute Renal Failure, Sepsis, Septic Shock
- Trial name
- ASK-IT (NCT00711789)
- Testing
- Angiotensin II
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Austin Health
Coronary Artery Stenosis
Kidney Damage In Patients With Severe Fall In eGFR
This is a pilot study using a randomized, double blinded, comparison of two iodinated contrast agents used during percutaneous coronary intervention (PCI).
- Trial name
- NCT01136915
- Testing
- Iopamidol 370, Iodixanol 320
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Bracco Diagnostics, Inc
Anesthesia, Spinal Aneshtesia
Renal Functions in Preeclamptic Pregnant Women Using Neutrophil Gelatinase-associated Lipocalin (NGAL) and Standard Renal Function Tests
Acute kidney injury (AKI) is a significant postoperative complication. Risk factors for AKI include impaired renal perfusion, decreased functional renal reserve, as well as advanced age, peripheral arterial disease, diabetes…
- Conditions
- Anesthesia, Spinal Aneshtesia, Acute Kidney Failure, Spinal Anesthesia Induced Hypotension
- Trial name
- NCT07015359
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Nihan Aydin Guzey
Cardiorenal Syndrome
Accuracy of Urinary NGAL in Predicting CardioRenal Syndrome in Acute Heart Failure at Emergency - CYNDERELA-HF Study
Rationale: Heart Failure (HF) elevated prevalence in Brasil and the world; 20-30% AHF patients develop CardioRenal Syndrome (CRS) type 1; Worsening Renal Failure (WRF) is a prognostic marker of mortality in Acute HF;NGAL is a…
- Trial name
- CYNDERELA-HF (NCT01364636)
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Pro-Cardiaco Hospital
Laparoscopic Colorectal Surgery, Acute Kidney Injury
The Effect of Fluid Management by Pleth Variability Index on Acute Kidney Injury in Obese Patients
This study was to find out whether laparoscopic colorectal surgery is detrimental to the kidneys via PVI monitoring. To detect the kidney injury, so-called kidney troponin NGAL ,which gives earlier information than creatin in…
- Trial name
- NCT03408834
- Testing
- pulse variability index
- Volunteers
- 29 people
- Sponsor
- Ankara University
Kidney Transplant; Complications, Acute Kidney Injury
Biomarkers NGAL, IL 18 as Predictors of Acute Kidney Injury in Renal Transplant Recipients
New markers of AKI including plasma Neutrophil Gelatinase Associated Lipocalin (NGAL) and Interleukin 18(IL-18) may form a biomarker panel that may help predict AKI earlier in the course of disease than creatinine.
- Trial name
- NCT03605264
- Volunteers
- 22 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Kidney Failure, Acute
Effects of Endothelin Receptor Antagonist on Ischemic Kidney Injury During Nephron Sparing Surgery
Based on animal studies, it was found that administration of endothelial receptor antagonists before and after renal blood vessels clamp and release results in a significantly reduced renal function injury.
- Trial name
- NCT04450095
- Testing
- Ambrisentan 10 MG
- Where
- 2 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Acute Kidney Injury
Neutrophil Gelatinase Associated Liocalin in Predicting AKI in Coronary Artery Disease
The aim of this work is to assess the clinical significance of serum levels of neutrophil gelatinase-associated lipocalin (NGAL) to predict AKI in patients exposed to PCI.
- Trial name
- NCT03266367
- Testing
- Neutrophil gelatinase-associated lipocalin (NAGL)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University
To Determine If Blood Level (NGAL) Could Accurately Early Detect Acute Renal Damage in All Patients Requiring Critical Care
NGAL in Prediction of AKI and Patient Outcomes
This single-center prospective non-randomized observational research included 120 critically ill persons, at Sohag University hospital's critical care unit.
- Trial name
- NGAL AKI (NCT06691607)
- Testing
- Serum NGAL level
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sohag University