Clinical trials: Nail Diseases
Onychomycosis
Human Factors Testing for OTC Use of the Erchonia® LunulaLaser
Human factors validation testing to assess the intended user's ability to correctly, safely, and effectively set-up, activate and operate the LunulaLaser™ OTC, to administer a treatment to a suitably qualified client, and to…
- Trial name
- NCT05626270
- Testing
- LunulaLaser OTC
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Erchonia Corporation
Onychomycosis
Deposition of Terbinafine After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subungual Onychomycosis in the Great Toenail
The purpose of this study is to determine how much terbinafine is delivered to the nail bed after treatment with a number of modifications to a previously studied method for iontophoretic delivery of terbinafine gel.
- Trial name
- NCT01484145
- Testing
- Terbinafine HCl
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nitric BioTherapeutics, Inc
Onychomycosis of Toenails
Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
The purpose of this study is to determine whether AN2690 topical solution is a safe and effective treatment for onychomycosis of the toenail.
- Trial name
- NCT01302119
- Testing
- AN2690 Topical Solution, 5%, Solution Vehicle
- Where
- 32 sites in United States, Canada
- Volunteers
- 604 people
- Sponsor
- Pfizer
Skin Condition, Hair Fragility
Assessment of Anti-aging Efficacy of Marine Collagen Peptides
To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
- Conditions
- Skin Condition, Hair Fragility, Nails, Ingrown
- Trial name
- NCT06306105
- Testing
- Marine Collagen Peptides
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Onychomycosis
Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail
The purpose of the study is to determine whether NB002, 0.25%, and 0.5% are safe and effective in the treatment of distal subungual onychomycosis of the toenail.
- Trial name
- NCT00453271
- Testing
- NB-002, Vehicle control
- Where
- 24 sites in United States, Canada
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- NanoBio Corporation
Arthrodesis, Bunion
Multi-Plane Hallux Valgus Correction With the Phantom® Nail
The goal of this research study is to determine the change in frontal plane rotation of the 1st metatarsal from pre to post arthrodesis of the 1st TMT joint with the Phantom® Intramedullary Nail combined with a supinating…
- Conditions
- Arthrodesis, Bunion, Hallux Valgus
- Trial name
- NCT04084262
- Testing
- Intramedullary Nail
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Paragon 28
Skin Laxity, Hair Thinning
Benefit of Bovine or Marine Collagen Vs. Placebo on Skin, Hair, Nails and Whole Body Health in Healthy Adults
The BECOME Study (Bovine and Marine Collagen Efficacy for Skin, Hair, Nails and Whole Body Health Markers Evaluation) is a randomized controlled trial designed to compare the effects of bovine and marine collagen supplements…
- Conditions
- Skin Laxity, Hair Thinning, Nails
- Trial name
- BECOME (NCT06603194)
- Testing
- Bovine or Marine Collagen
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ancient + Brave
Onychomycosis
Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail
The purpose of the study is to determine the safety and efficacy of 5.0% AN2690 Solution in the treatment of distal, subungual onychomycosis of the great target toenail.
- Trial name
- NCT01278394
- Testing
- AN2690 Solution, 5.0%
- Where
- 2 sites in Mexico
- Volunteers
- 29 people
- Sponsor
- Pfizer
Onychomycosis, Toe
Scoring Clinical Index For Onychomycosis in Toenail Onychomycosis Treating With Itraconazole Capsules
The purpose of this study is to evaluate the participants with toenail onychomycosis (fungal infection of the nail) confirmed positive by potassium hydroxide (KOH) and bacterial identification test after administration of…
- Trial name
- NCT00871728
- Testing
- Itraconazole
- Volunteers
- 132 people
- Sponsor
- Janssen Korea, Ltd., Korea
Onychomycosis
The Efficacy of CELEXT07 in the Treatment of Toenail Onychomycosis
This will be an interventional safety and efficacy study of CELENT07 when used as a topical treatment of onychomycosis in the toenails (tinea unguium) of adults 18 years and older.
- Trial name
- NCT02644551
- Testing
- CELEXT07, Penlac, vehicle solution
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- 9305-9954 Quebec Inc
Pachyonychia Congenita
A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita
PALV-08 is a multicenter, open-label treatment (OLT) study enrolling adults with Pachyonychia Congenita (PC) with genotyped keratin mutations KRT6A, KRT6B, KRT6C or KRT16 who were previously enrolled in the PALV-05 (VAPAUS)…
- Trial name
- NCT05643872
- Testing
- PTX-022
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Palvella Therapeutics, Inc.
Onychomycosis
Topical Gel Anti-Fungal Agent for Tinea Unguium
The purpose of this study is to compare, in a controlled fashion, the response to two anti-fungal agents, naftifine or terbinafine, with vehicle in novel topical gel formulations in the treatment of subjects with distal subungual…
- Trial name
- NCT00253305
- Testing
- Organogel of naftifine, 2%, Organogel of terbinafine, 2%, Organogel of naftifine, 6%
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- MediQuest Therapeutics
Psoriasis
A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis
The primary objectives of the study are to 1) compare the efficacy responses of CP 690,550 (5 mg BID and 10 mg BID) versus placebo following 24 weeks of CP 690,550 treatment and subsequent withdrawal of active treatment at…
- Trial name
- NCT01186744
- Testing
- CP-690,550
- Where
- 87 sites in United States, Argentina and 10 more
- Volunteers
- 666 people
- Sponsor
- Pfizer
Onychomycosis of Toenail
Safety and Efficacy of Next Science Gel on Toenail Fungus
This is a 52 week, 20-patient open-label pilot study on the safety and efficacy of Next Science Wound gel in the treatment of mild to moderate Distal Subungual Onychomycosis.
- Trial name
- NCT04042857
- Testing
- Next Science Treatment Gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Next Science TM
Onychomycosis
Effectiveness and Safety of Nailner Brush 2in1 in Onychomycosis
Evaluate the effectiveness of Nailner Brush 2-in-1 in the treatment of onychomycosis based on the blinded evaluation of the percentage of healthy nail surface after 6 months of treatment compared to baseline.
- Trial name
- NCT05560841
- Testing
- topical treatment
- Where
- 2 sites in Tunisia
- Volunteers
- 50 people
- Sponsor
- Karo Pharma AB
Fingernail Psoriasis
Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis
The purpose of this clinical study is to compare the efficacy and safety of three concentrations of topical methotrexate for the treatment of fingernail psoriasis.
- Trial name
- NCT00666354
- Testing
- Methotrexate
- Where
- 7 sites in United Kingdom
- Volunteers
- 83 people
- Sponsor
- MediQuest Therapeutics
Onychomycosis
Efficacy Study of LIQUICURE™ to Treat Toe Nail Fungus
There is a major clinical need for an inexpensive topically-applied product that can inhibit the growth of the dermatophytes that cause nail fungus.
- Trial name
- CT001 (NCT00960089)
- Testing
- LIQUICURE
- Where
- 4 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Chesson Laboratory Associates, Inc
Distal Subungual Onychomycosis, Fungal Infection
A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail
This study will be a multicenter, international, randomized, vehicle-controlled, parallel-group, double-blinded study. Subjects who are eligible to participate with a confirmed diagnosis of Distal Subungual onychomycosis (DSO) of…
- Conditions
- Distal Subungual Onychomycosis, Fungal Infection, Fungus, Nail
- Trial name
- NCT04188574
- Testing
- BB2603-1, BB2603-3, BB2603-10
- Where
- 20 sites in Czechia, Germany and 1 more
- Volunteers
- 111 people
- Sponsor
- Blueberry Therapeutics
Onychomycosis
A Trial of the Safety and Efficacy of EcoNail™ in the Treatment of Fungus Infections of the Great Toenail
Approximately 40 qualified subjects with mild-to-moderate great toenail fungus infection will be treated for 48 weeks with lacquer application to at least one affected great toenail.
- Trial name
- NCT00385502
- Testing
- EcoNail™ (econazole 5%/SEPA® 18% nail lacquer)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Abeona Therapeutics, Inc
Moderate to Severe Nail Psoriasis
Study of Safety, Tolerability, and Efficacy of Secukinumab in Subjects With Moderate to Severe Nail Psoriasis
This purpose of this study was to demonstrate the efficacy of secukinumab versus placebo on nail psoriasis and to assess long-term efficacy, safety and tolerability of secukinumab.
- Trial name
- TRANSFIGURE (NCT01807520)
- Testing
- Secukinumab
- Where
- 40 sites in United States, Australia and 7 more
- Volunteers
- 198 people
- Sponsor
- Novartis Pharmaceuticals