Clinical trials: Nail Diseases
Fluorosis, Dental
Nails and Teeth as Biomarkers of Fluoride Exposure
To determine fluoride concentration in fingernails and estimate if there is a correlation between fluoride concentration in fingernails and fluoride concentration in toothpaste used.
- Trial name
- NCT05442320
- Testing
- Biodent Toothpaste (Ilirija d.d., Ljubljana, Slovenia)
- Volunteers
- 342 people
- Sponsor
- University of Ljubljana
Vitiligo, Healthy
Dermoscopy in Nails
Study types and frequency of nail changes in patients with vitiligocompared to healthy subjects
- Trial name
- NCT06696612
- Testing
- Dermoscopy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intestinal Parasitic Infections, Anaemia
Impact of Hand Hygiene Activities on the Prevention of Intestinal Parasitic Infections and Anaemia Among School Children
Impact exerted by intestinal parasitic infections is much higher in developing countries. School-aged children are at higher risk from the burden of disease, because they specially have many parasitic infections.
- Trial name
- NCT01619254
- Testing
- Hand washing with soap and hand finger nail clipping
- Where
- Ethiopia
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Mekelle University
Onychomycosis
A Retrospective Analysis of the Effects of Low Level Laser Therapy on Toenail Onychomycosis
The purpose of this study is to determine whether low level laser therapy (LLLT) using the Erchonia LUNULA device is effective in increasing clear nail in toenails with onychomycosis.
- Trial name
- NCT02588599
- Testing
- Erchonia LUNULA
- Volunteers
- 54 people
- Sponsor
- Erchonia Corporation
Ingrown Toenail, Virtual Reality
Virtual Reality in Ingrown Toenail Surgery
Ingrown toenail is a common condition that may cause significant pain, functional impairment, and recurrent disease. Although conservative management is appropriate for mild cases, moderate-to-severe or recurrent ingrown toenails…
- Trial name
- NCT07707726
- Testing
- Virtual Reality (VR)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent
Ingrown Toenails, Ingrown Nail Inflammation
Evaluation of Apaisant Serum - Ingrown Nails for Ingrown Toenails
To open-label clinical study aims to evaluate the efficacy and safety of APAISANT SERUM - INGROWN NAILS, a Class IIa CE-marked medical device, in relieving pain and discomfort associated with inflamed ingrown nails.
- Trial name
- NCT07041047
- Testing
- APAISANT SERUM - INGROWN NAILS
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Swiss Footcare Laboratories - Poderm Professional
Onychomycosis
CLINICAL INVESTIGATION FOR THE EVALUATION OF EFFICACY AND SAFETY OF TWO PRODUCTS FOR THE TREATMENT OF ONYCHOMYCOSIS
The efficacy and safety of ENRICHED (X92001591) will be evaluated in a multicentric, randomized, evaluator blinded clinical investigation in 88 patients.
- Trial name
- NCT06689852
- Testing
- Enriched, Loceryl 5%
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Oystershell NV
Breast Cancer, Nail Toxicity
Taxane Chemotherapy and Nail Toxicity in Women With Breast Cancer; Stage Two: Evaluation of Interventions
The study compares three strategies to prevent/minimise nail problems occuring in women, with breast cancer, undergoing Taxane chemotherapy.
- Trial name
- NCT02583204
- Testing
- Onicolife nail drops, Nail polish
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- NHS Greater Glasgow and Clyde
Arthritis; Psoriasis (Etiology)
Assessment of the Clinical and Ultrasound Response to Apremilast by Clinical Evaluation and by a Joint-periarticular-nail Ultrasound Index in Patients With Active Psoriatic Arthritis
This study aims to evaluate more objectively, through an imaging technique such as ultrasound, changes in joints and entheses of patients with active psoriatic arthritis (PAs) who will start treatment with Apremilast after the…
- Trial name
- APREMILAST (NCT03191539)
- Testing
- Apremilast
- Volunteers
- 56 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Psoriasis
Efficacy and Safety Study of NP000888 in Subjects With Plaque and Nail Psoriasis
This study is to evaluate the efficacy and safety of topical application of NP000888 ointment compared to vehicle in plaque and fingernail psoriasis subjects. Duration of administration: 24 weeks
- Trial name
- NCT02995473
- Testing
- NP000888, Vehicle
- Where
- 10 sites in Taiwan
- Volunteers
- 61 people
- Sponsor
- Galderma R&D
Psoriasis Chronic
Quality of Life in Adalimumab Treated Psoriasis Patients Failing Other Biologic Disease Modifying Anti-rheumatic Drugs
The aim of this post-marketing observational study (PMOS) was to obtain further data on long-term safety, efficacy, and quality of life outcomes for adalimumab in routine clinical use in participants with moderate to severe…
- Trial name
- QUALITY (NCT01084668)
- Where
- 9 sites in Austria
- Volunteers
- 46 people
- Sponsor
- Abbott
Ingrowing Nail With Infection
Patient Satisfaction After Ingrown Toenail Surgery
In this study, demographic characteristics (age, gender, which toe is involved, family history) of the patients who were operated because of ingrown nails were examined, and the post-operative satisfaction score of the patients…
- Trial name
- NCT05062616
- Testing
- Toenail surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 1,200 people
- Sponsor
- Goztepe Training and Research Hospital
Dermatophytosis, Tinea Corporis
In Vitro Susceptibility of Dermatophytes to Terbinafine and Itraconazole: MIC Distributions and Elevated-MIC Isolates in Faisalabad, Pakistan
Dermatophyte infections of the skin, hair and nails are common in Pakistan, and treatment failure with standard antifungal drugs is increasingly reported.
- Conditions
- Dermatophytosis, Tinea Corporis, Tinea Cruris, Tinea Pedis
- Trial name
- NCT07898475
- Testing
- In vitro antifungal susceptibility testing
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Dr. Amara Safdar
Connective Tissue Disease, Dissecting Aneurysm
Study of Heritable Connective Tissue Disorders
The purposes of this study are to identify the genes responsible for inherited connective tissue disorders and learn about the range of medical problems they cause.
- Conditions
- Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome
- Trial name
- NCT00001641
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Psoriasis Vulgaris, Psoriasis
Tofacitinib Ointment For Chronic Plaque Psoriasis
The study is beng done to test if tofacitinib ointment is safe and effective for people with plaque psoriasis. Two dose strengths of tofacitinib ointment (20 mg/g and 10 mg/g) applied once or twice daily are being tested.
- Trial name
- NCT01831466
- Testing
- tofacitinib ointment 20 mg/g, tofacitinib ointment 10 mg/g
- Where
- 54 sites in United States, Canada and 2 more
- Volunteers
- 476 people
- Sponsor
- Pfizer
Bone Metastases, Lymphoma
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing…
- Conditions
- Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use
- Trial name
- NCT03823534
- Testing
- Ketorolac, Normal saline, Acetaminophen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University
Onychomycosis
Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis Patients
This study is Randomized, Double-Blind, Vehicle-Controlled, Multiple-Dose Study. The purpose is to determine the safety, tolerability, systemic exposure and pharmacokinetics of ME1111 after repeated daily topical application of…
- Trial name
- NCT01841996
- Testing
- ME1111 solution, Vehicle Solution
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Fungal Infection, Onychomycosis
An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection
The goal of the current study is to evaluate the ability of CGB-400, a proprietary eutectic mixture of GRAS compounds, to clear the toenail fungal growth and improve the appearance of the fungus affected area(s).
- Conditions
- Fungal Infection, Onychomycosis, Tinea Unguium
- Trial name
- NCT05202366
- Testing
- CGB-400 Topical Gel
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- CAGE Bio Inc.
Tibial Fractures
Compartmental Overpressures Associated to Reamed Intramedullary Nails
The purpose of this study is to determine the effect of reamed intramedullary nails in tibial shaft fractures (as a standard treatment), in raising intracompartmental pressures and therefore determine if they are a risk factor…
- Trial name
- NCT00842101
- Testing
- Quick Pressure Monitor
- Where
- Andorra
- Volunteers
- 80 people
- Sponsor
- University of Andorra
Onychomycosis
Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis
The purpose of the study is to evaluate and compare the efficacy of the sequential association RV4104A ointment followed by ciclopiroxolamine 1% cream and ciclopirox 8% film-forming solution versus amorolfine 5% nail lacquer…
- Trial name
- ONICO (NCT01014637)
- Testing
- Amorolfine (Antifungal), RV4104A, Ciclopiroxolamine, Cyclopirox (Keratolytic Agents/Antifungal)
- Where
- 7 sites in France
- Volunteers
- 260 people
- Sponsor
- Pierre Fabre Dermo Cosmetique