Clinical trials: Nano-hydroxyapatite
Molar-Incisor Hypomineralization (MIH)
Color Change and Desensitization of Molar Incisor Hypomineralization-Affected Enamel Using Biomimetic Nano-Hydroxyapatite Toothpaste
This clinical trial aims to evaluate if nano-hydroxyapatite (Nano-HA) toothpaste effectively treats children with Molar-Incisor Hypomineralization (MIH). It will also assess the safety of Nano-HA toothpaste.
- Trial name
- NCT07436039
- Testing
- Fluoridated Toothpaste, Nano-hydroxyapatite Toothpaste
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdulaziz University
Alveolar Bone Resorption, Socket Preservation
Efficacy Of Eggshell-Derived Nanohydroxyapatite Based Mineralized Plasmatic Matrix Versus Xenogeneic Based Mineralized Plasmatic Matrix in Posterior Mandibular Socket Preservation
After tooth extraction, the alveolar bone, which supports the teeth, undergoes a natural resorption process. This bone loss can be significant, especially in the first few months post-extraction, leading to a reduction in both…
- Conditions
- Alveolar Bone Resorption, Socket Preservation, Wound Healing, Nano-hydroxyapatite
- Trial name
- NCT07404098
- Testing
- Socket preservation using eggshell-derived nanohydroxyapatite-based mineralized plasmatic matrix along with platelet-rich fibrin (PRF)., Socket preservation using deproteinized bovine bone mineral (DBBM) xenograft along with platelet-rich fibrin (PRF).
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Marginal Integrity of Hydroxyapatite Nanofiber Reinforced Flowable Composite
Evaluation of Marginal Integrity of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional Resin-Based Flowable Composite in Initially Demineralized Pits and Fissure: A One Year, Randomized Clinical Trial
This study will be conducted to evaluate the Marginal integrity of Hydroxyapatite Nanofiber reinforced flowable composite compared to a conventional resin-based flowable composite during management of initial carious lesion in…
- Trial name
- NCT03242291
- Testing
- Conventional resin-based flowable composite, Hydroxyapatite Nanofiber reinforced flowable composite
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion
Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite
Dental caries is a common oral disease. The process of caries formation is a cycle of remineralization and demineralization with various stages being either reversible or irreversible.
- Trial name
- NCT05771077
- Testing
- Poly(Amidoamine) dendrimer
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Egymedicalpedia
Dentin Sensitivity
Use of Biomaterials as Desensitizer Agents
Aim: to investigate the clinical effectiveness over 12 weeks of three different biomaterials, nano-hydroxyapatite based, in the therapy of the dental sensitivity.
- Trial name
- NCT02770573
- Testing
- Cavex Bite&White ExSense, Kuraray Teethmate™ Desensitizer, Ghimas Dentin Desensitizer
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Università degli Studi di Sassari
Dental Caries in Children, Cariostatic Agent
Cariostatic and Remineralizing Effects of Three Different Dental Varnishes
This study is a randomly, controlled, prospective in vivo study. The objective of this study is: To evaluate the cariostatic and re-mineralizing effects of Nano silver fluoride, Nano Hydroxyapatite and sodium fluoride varnishes…
- Conditions
- Dental Caries in Children, Cariostatic Agent, Resistance, Dental Caries, Fluoride Varnishes
- Trial name
- NCT04887389
- Testing
- Nano Silver Fluoride varnish, nano-hydroxyapatite varnish, sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Nisreen Ibrahim khan
Bone Resorption
Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Alendronate in the Preservation of the Tooth Socket
Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in teh research project, which TEMPhas more TEMPthan 20 teeth, are over 18 years old and…
- Trial name
- NCT03980847
- Testing
- Alendronate 20 mg, Nanocrystal hydroxyapatite
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Maxillary Sinus Augmentation
Open Maxillary Sinus Augmentation Using Different Types of Bone Particles
Two stage sinus lifting using Nano hydroxyapatite particles [Nanostreams] versus Deprotenized bovine bone [Tutogen] : Randomized clinical trial. comparing between Height of new bone formation, Bone area percent( Histomorphometric)
- Trial name
- NCT03184857
- Testing
- open maxillary sinus lifting
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Dentin Sensitivity
Nano-hydroxyapatite With Potassium Nitrate in the Therapy of the Dental Sensitivity
The chief aim of this study is to evaluate the difference in tooth sensitivity after having used a gel containing nano - hydroxyapatite and potassium nitrate This randomized double-blind clinical study is designed to compare the…
- Trial name
- NCT02895321
- Testing
- Cavex Bite&White ExSense, Colgate, Protection Caries
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Università degli Studi di Sassari
Periodontitis, Intrabony Periodontal Defect
Clinical Evaluation of Nano-Hydroxyapatite as an Adjunctive to Minimally Invasive Non-Surgical Technique in the Treatment of Deep Intra-bony Defects
This randomized controlled clinical trial aims to evaluate the effectiveness of using nano-hydroxyapatite (nHA) gel alongside a minimally invasive non-surgical technique (MINST) to treat deep intra-bony defects in patients with…
- Trial name
- MINST (NCT07608783)
- Testing
- Minimally invasive non-surgical technique (MINST), nano-hydroxyapatite
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Chitosan, Nano-hydroxyapatite Hydrogel
Chitosan Nano-hydroxyapatite Hydrogel in Non-Surgical Treatment of Intrabony Defect
The aim of this study was to evaluate the clinical effect of Chitosan with nano-hydroxyapatite hydrogel in the treatment of periodontal intrabony defects.
- Conditions
- Chitosan, Nano-hydroxyapatite Hydrogel, Intrabony Defect
- Trial name
- NCT06373757
- Testing
- Nano-HAP/Chitosan hydrogel
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- October 6 University
Dentin Sensitivity
Effect of Nano-hydroxyapatite and LASER on Dentin Hypersensitivity
The aim of this study was to evaluate the effect of nanohydroxyapatite associated with low potency laser therapy in eliminating or reducing dentin hypersensitivity in a randomized placebo-controlled clinical trial.
- Trial name
- NCT03637426
- Testing
- Laser, nano-hydroxyapatite, Laser + nano-hydroxyapatite
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para