Clinical trials: Narcotic Consumption, active
Opioid Consumption, Postoperative, Pain After Surgery
Preoperative Opioid Tapering Before Spine Surgery
This is a pilot study in which patients taking opioids chronically who are scheduled for spine surgery at least 4 weeks in advance will be randomly assigned to one of two groups: opioid tapering with education alone or opioid…
- Conditions
- Opioid Consumption, Postoperative, Pain After Surgery, Opioid Dependency
- Trial name
- NCT07221786
- Testing
- Opioid tapering with CBT and education, Opioid tapering with education alone
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Thomas Jefferson University
ACL Repair
The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumption in Patients Undergoing Autograft ACL Reconstruction
The purpose of the research is to investigate the effect of preoperative Cryoneurolysis of the knee on postoperative pain management in patients undergoing autograft anterior cruciate ligament (ACL) reconstruction (a surgical…
- Trial name
- NCT06603051
- Testing
- Cryoneurolysis
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Virtua Health, Inc.
Postoperative Pain, Nausea and Vomiting, Postoperative
Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks
The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control…
- Conditions
- Postoperative Pain, Nausea and Vomiting, Postoperative, Dizziness, Constipation
- Trial name
- Dex-Dex PNB (NCT07099222)
- Testing
- Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks, Ropivacaine with low, non weight based Dexamethasone additive
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Opioid Use Disorder, Opioid Consumption
Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery
The mechanisms leading to opioid tolerance or dependence are not well understood and there are currently no biomarkers for predicting who is at risk for development of OUD.
- Conditions
- Opioid Use Disorder, Opioid Consumption, Persistent Opioid Use, Persistent Postsurgical Pain
- Trial name
- NCT07693270
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Opioid Abuse (Disorder), Opioid Analgesia
Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity
The goal of this clinical trial is to evaluate strategies for optimizing postoperative multimodal pain regimens and reducing opioid dependency in patients undergoing upper extremity surgery.
- Conditions
- Opioid Abuse (Disorder), Opioid Analgesia, Opioid Analgesic Adverse Reaction, Opioid Consumption
- Trial name
- NCT07750639
- Testing
- Naproxen, Acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- AdventHealth