Clinical trials: Nasal Allergies
Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis
Bioequivalence Study of Azelastine Hydrochloride/ Fluticasone Propionate 137 Microgram/50 Microgram Nasal Spray and Dymista Nasal Spray
Single dose (four sprays) bioequivalence study of Azelastine Hydrochloride/ Fluticasone Propionate 137 microgram/50 microgram Nasal Spray and 'DYMISTA' (Azelastine Hydrochloride/Fluticasone Propionate) Nasal Spray 137…
- Trial name
- NCT06180083
- Testing
- Azelastine Hydrochloride/ Fluticasone propionate nasal spray, 'DYMISTA' NASAL SPRAY
- Where
- India
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Perennial Allergic Rhinitis
Safety Study of Olopatadine Nasal Spray
The purpose of this study is to determine whether olopatadine nasal spray is safe and effective when used for up to one year by patients with perennial allergic rhinitis.
- Trial name
- NCT00578331
- Testing
- Olopatadine 0.6% nasal spray
- Where
- United States
- Volunteers
- 890 people
- Sponsor
- Alcon Research
Asthma, Seasonal Allergic Rhinitis
The Role of Pollen Starch Granules in Pollen Challenge Studies in the Fraunhofer Environmental Exposure Unit
The aim of the study is to explore the contribution of pollen starch granules to the induced symptoms and airway inflammation in patients with allergic rhinitis and mild asthma in a controlled pollen exposure(pollen challenge…
- Trial name
- NCT00209365
- Testing
- exposure to grass pollen/starch granules
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Asthma, Allergic Rhinitis
Fractional Exhaled Nitric Oxide (FeNO) Result Prediction Factors in Children With Allergic Diseases
In about 800 children with allergic diseases (asthma, allergic rhinitis, atopic dermatitis) the investigators will retrospectively and cross-sectionally analyze the influence/correlation of diagnosis, treatment methods, allergy…
- Conditions
- Asthma, Allergic Rhinitis, Atopic Dermatitis
- Trial name
- NCT00815984
- Testing
- measurements of lung function tests
- Where
- Poland
- Volunteers
- 800 people
- Sponsor
- Medical University of Lodz
Eosinophilic Esophagitis
Allergy Immunotherapy in the Management of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a disease that has increased in incidence over the past decade that affects males predominantly, and in adults, is characterized by heartburn, dysphagia, strictures and food impactions.
- Trial name
- AIMEE (NCT01685034)
- Testing
- Allergy immunotherapy ("allergy shots")
- Sponsor
- United States Naval Medical Center, San Diego
Allergic Rhinitis, Asthma
Safety and Efficacy of Small Extracellular Vesicles Nebulizer in Patients With Allergic Rhinitis Complicated With Asthma
This trial aims to evaluate the safety, tolerability and efficacy of hUC-MSC-sEV-002 nebulizer in patients with allergic rhinitis and asthma.
- Trial name
- NCT07453771
- Testing
- hUC-MSC-sEV-002 Nebulizer, hUC-MSC-sEV-002 Mimetic (Normal Saline)
- Where
- 5 sites in China
- Volunteers
- 18 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Pollen Allergy
Identification of Allergen-reactive Antibodies in the Blood of Pollen Allergic Patients
The project examines the hypothesis that monoclonal allergen-neutralizing antibodies can be recombinantly produced from B lymphocytes isolated from pollen allergic patients.
- Trial name
- NCT03727399
- Testing
- blood withdrawal
- Where
- Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mabylon AG
Healthy Individuals, Allergic Rhinitis
Health Effects of Wood Smoke and Traffic-Related Air Pollution Exposures: a Necessary Comparison
Accumulating evidence demonstrates that breathing air pollutants leads to devastating increases in sickness and death worldwide over time.
- Trial name
- WADE (NCT06749093)
- Testing
- Filtered Air (FA), Wood Smoke (WS), Diesel Exhaust (DE)
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Perennial Allergic Rhinitis
Effects of Pine Cone Extract on Serum IgE Levels in Perennial Rhinitis
The medicinal properties of pinecones have been used for years to treat a variety of illnesses. In the mouse model, an extract of pine cones, poly-phenylpropanoid-polysaccharide complex (PPC), has been shown to reduce total serum…
- Trial name
- PCE (NCT04024033)
- Testing
- pine cone extract
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of South Florida
Allergic Rhinitis
Assess the Efficacy and Safety of Rhinocort Aqua
The purpose of this study is to compare Rhinocort with placebo in pediatric subjects aged 2-5 years with allergic rhinitis to study effects on nasal symptoms such as sneezing, runny and stuffy noses.
- Trial name
- NCT00641693
- Testing
- Budesonide
- Volunteers
- 650 people
- Sponsor
- AstraZeneca
Asthma, Allergic Rhinitis
PF and FeNO and Clinical Characteristics in Children Being Diagnosed Due to Suspicion of Allergic Diseases
The aim of this study is to assess the influence of kind of allergic disease, allergic profile, allergen exposure, treatment method on lung function parameters, fractional exhaled nitric oxide level in children suspected and…
- Conditions
- Asthma, Allergic Rhinitis, Atopic Dermatitis, Urticaria
- Trial name
- NCT01805635
- Testing
- No intervention
- Where
- Poland
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Allergic Rhinitis, Rhinitis, Allergic, Seasonal
Investigate Two Trial Models; Vienna Challenge Chamber (in and Out of Season) and Park Study (in Season) Using a Drug for Seasonal Allergic Rhinitis
The aim of the study is to investigate the trial models, Vienna Challenge Chamber (VCC), in and out of season, and Park Study in season and the clinical efficacy of repeat doses of fluticasone propionate in subjects with seasonal…
- Trial name
- NCT00400998
- Testing
- Fluticasone Propionate
- Where
- Austria
- Volunteers
- 41 people
- Sponsor
- Research Consult GmbH
Rhinitis, Allergic, Seasonal
Investigation Of a New Oral Anti-Histamine in Healthy Male Subjects
This study is designed to assess the safety and tolerability of single, escalating oral doses and repeat oral doses (7 days, once daily) of GSK835726 in healthy male subjects
- Trial name
- NCT00605852
- Testing
- GSK835726
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma; Allergic Rhinitis
Tolerability and Pharmacokinetics of CSPCHA115 Capsules in Chinese Healthy Volunteers
A randomized, single-center, double-blind, ascending multiple-dose, placebo-controlled study to evaluate the tolerability and pharmacokinetics of CSPCHA115 capsules in Chinese healthy volunteers.
- Trial name
- NCT04161547
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Seasonal Allergic Rhinitis
A Study Comparing the Bioequivalence of Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray (Apotex, Inc.) to That of Dymista™ Nasal Spray (Meda Pharmaceuticals, Inc.) in the Treatment of Seasonal Allergic Rhinitis
This study is to evaluate the equivalence of generic Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray with that of the marketed drug, Dymista™ Nasal Spray, in the treatment of seasonal allergic rhinitis, and to…
- Trial name
- NCT02279563
- Testing
- Azelastine HCl and Fluticasone Propionate Nasal Spray, 137 µg/50 µg per spray, Dymista™ Nasal Spray
- Volunteers
- 595 people
- Sponsor
- Apotex Inc.
Allergic Rhinitis
Revaccination With Pollinex® Quattro
The purpose of this non interventional study (NIS) was to observe the efficacy of Pollinex® Quattro as a short-term revaccination in patients who have already been successfully desensitized at least five years ago against…
- Trial name
- NCT02579720
- Volunteers
- 108 people
- Sponsor
- Prof. Dr. Ralph Mösges
Rhinitis, Allergic, Perennial
Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR)
The primary objective of this study is to compare the efficacy and safety of GW685698X 100mcg once daily (QD) aqueous nasal spray with vehicle placebo nasal spray in adult and adolescent subjects (12 years of age and older) with…
- Trial name
- NCT00289198
- Testing
- FF
- Where
- 42 sites in United States, Australia and 7 more
- Volunteers
- 301 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis/Rhinoconjunctivitis +-Intermittent Asthma, Sensitization Against Betula Alba (Birch) Pollen
Depigoid Birch 5000 Longterm Study in Adults and Adolescents
Specific immunotherapy for IgE mediated sensitization to birch pollen. Long-term study to assess safety and efficacy of Depigoid(R)Birch 5000 - a modified pollen extract of Betula alba (Birch) - versus placebo.
- Trial name
- NCT01694836
- Testing
- s.c. injection
- Where
- 2 sites in Germany
- Volunteers
- 634 people
- Sponsor
- Leti Pharma GmbH
Seasonal Rhinitis and/or Rhinoconjunctivitis, Birch Pollen Allergy
SUBLIVAC® Birch PROBE Study
Objective of the study is to show, on an exploratory basis, that treatment with SUBLIVAC Birch is also effective compared to treatment with Staloral Birch by means of reduction in allergic symptoms during nasal provocation in…
- Trial name
- NCT00932607
- Testing
- sublingual immunotherapy
- Where
- Germany
- Volunteers
- 74 people
- Sponsor
- HAL Allergy
Thoracic Surgery
PCR Technique to Identify Methicillin-sensitive and Methicillin-resistant Staphylococcus Aureus in Nasal and Respiratory Tract Samples
In patients on mechanical ventilation, it is not known whether the identification of S. aureus in LRT samples improves the performance of its nasal detection.
- Trial name
- NCT02640001
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Emilio Bouza