Clinical trials: Nasal Cannula
Thoracic Surgery, Respiratory Failure
High Flow Nasal Cannula in Thoracic Surgery: a Physiologic Study
The goal of this study is to evaluate the role that high-flow nasal cannulas (HFNC) have on respiratory drive, work of breathing and neuromuscular efficiency after lung resection surgery.
- Trial name
- NCT03877172
- Testing
- High-flow nasal cannula
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Clinic of Barcelona
Acute Respiratory Failure
High Flow Nasal Cannulas in Children
Non-invasive Continuous Positive Airway Pressure (nCPAP) is widely recognized as an efficient respiratory support in infants with mild to moderate Acute Hypoxemic Respiratory Failure (AHRF).
- Trial name
- HFNC (NCT03689686)
- Testing
- Noninvasive Respiratory Support
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
COVID 19
Use of the Nasal Cannula During COVID-19
The objective of this investigation is to determine the incidence of the use of the low flow nasal cannula in suspected or confirmed cases with Covid-19
- Trial name
- NCT04376580
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tiva Group
Hypoxemia, Conscious Sedation
Impact of Nasal Mask Versus Nasal Cannula Oxygenation on Hypoxemia in Gastrointestinal Endoscopy: A Brain Function Monitoring (SedLine)-Guided Randomized Controlled Trial (NAMSHIC)
This randomized controlled trial compared the efficacy of a nasal mask versus a standard nasal cannula for oxygen delivery during gastrointestinal endoscopic procedures performed under target controlled propofol infusion…
- Trial name
- NAMSHIC (NCT07500779)
- Testing
- Nasal Mask Oxygenation, Nasal Cannula Oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Respiratory Distress Syndrome, Newborn
RAM Cannula Versus Short Bi-nasal Cannula in Respiratory Distress Syndrome
Noninvasive ventilation defines methods of providing ventilation support with constant or variable pressure using nasal or nasopharyngeal interfaces without endotracheal intubation or tracheostomy.
- Trial name
- NCT03366714
- Testing
- nasal CPAP support with RAM cannula, nasal CPAP support with Hudson cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Infant, Newborn, Disease, Hypoxia
CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial
The purpose of this study is to determine if in preterm infants < 34 weeks' gestation at birth receiving respiratory support with continuous positive airway pressure (CPAP) or nasal cannula (NC), CPAP compared with NC will…
- Conditions
- Infant, Newborn, Disease, Hypoxia, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
- Trial name
- COCO (NCT04792099)
- Testing
- Continuous positive airway pressure, Nasal Cannula
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Alabama at Birmingham
Hypoxemia
The Correlation Between Sleep Quality and Atrial Fibrillation Undergoing High-flow Nasal Cannula Oxygen (HFNC)
The investigators hypothesized that heated humidified high-flow nasal cannula oxygen(HFNC) along with high quality of sleep, in comparison with noninvasive positive pressure ventilation (NIV), could reduce the release of…
- Trial name
- NCT02713737
- Testing
- heated humidified high-flow nasal cannula, noninvasive ventilation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Airway Disorder
Optimizing High Flow Nasal Cannula Oxygenation in Pediatric Airway Procedures
The purpose of this study is to investigate which flow rate (higher versus lower) is most effective at increasing apneic time and preventing greater than 5% drop in desaturation, as well as assessing transcutaneous carbon dioxide…
- Trial name
- NCT06947902
- Testing
- High flow, Low Flow
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Swallowing Disorder, Respiratory Insufficiency
The Impact of High-Flow Nasal Cannula on Swallow Function
Background: High-flow nasal cannula (HFNC) is a non-invasive heated and humidified oxygen delivery device that is capable of delivering high-flow rates.
- Trial name
- NCT03590457
- Testing
- Airvo 2; High-Flow nasal cannula system
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Apneic; Oxygenation
Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient
This prospective, randomized, double-blind study is intended to enroll a total of 100 patients with a BMI ≥ 40 kg/m2 and another 100 patients with a BMI ≥ 30 kg/m2 (but less than 40 kg/m2) undergoing surgery with general…
- Trial name
- NCT03671837
- Testing
- Oxygen, Air
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Respiratory Failure, Hypoxemia
High-flow Nasal Cannula vs. Helmet PSV vs. Helmet CPAP During Respiratory Failure
The investigators designed a cross-over, randomized trial to assess the physiological effects of helmet pressure support ventilation (PSV) and continuous positive airway pressure (CPAP) as compared to high-flow nasal cannula…
- Trial name
- HIGHFLOWHELMET (NCT04241861)
- Testing
- Respiratory support (High-flow oxygen therapy), Respiratory support (Helmet PSV), Respiratory support (Helmet CPAP)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
De Novo Hypoxemic Acute Respiratory Failure (hARF)
Impact on Mortality of a Strategy Including Continuous Positive Airway Pressure Plus High Flow Nasal Cannula Oxygen Therapy Versus High Flow Nasal Cannula Oxygen Therapy Alone in Patients With de Novo Acute Hypoxemic Respiratory Failure: a Prospective, Randomized Controlled Trial.
De novo hypoxemic acute respiratory failure (hARF) is one of the main causes of intensive care unit (ICU) admission. In de novo hARF, intubation is associated with a dramatic increase in mortality rate.
- Trial name
- HighCPAP (NCT06213168)
- Testing
- HFNC, CPAP and HFNC
- Where
- 29 sites in France
- Volunteers
- 1,084 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Care, High-flow Nasal Cannula Oxygen
Effect of High-flow Nasal Cannula Oxygen on Lung Volumes Determined by Electrical Impedance Tomography
Effect of High-flow nasal cannula oxygen on end-expiratory lung volumes determined by electrical impedance tomography
- Conditions
- Critical Care, High-flow Nasal Cannula Oxygen, Electrical Impedance Tomography, End Expiratory Lung Volume
- Trial name
- OXIDIA (NCT02186288)
- Testing
- High-flow nasal cannula oxygen
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atelectasis
Prevention of Atelectasis, Via High Flow Nasal Cannula to Obtain a PEP, During General Anesthesia in Children
Anesthesia causes respiratory changes and complications, which are the main causes of complications and anesthesia-related deaths.
- Trial name
- PREVAT-PED (NCT03592589)
- Testing
- high flow nasal canula
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Hypoxemic Respiratory Failure, Acute Hypercapnic Respiratory Failure
Asymmetrical Versus Conventional High-flow Nasal Cannula in Acute Respiratory Failure
The goal of this randomized crossover physiological study is to evaluate the physiologic effects of asymmetrical nasal cannula and conventional nasal cannula in patients with acute respiratory failure.
- Trial name
- NCT06204276
- Testing
- Experimental: Asymmetrical high-flow nasal cannula, Active comparator: Conventional high-flow nasal cannula
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Siriraj Hospital
High-Flow Nasal Cannula, COPD
Effect of Postextubation High-Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypercapnic COPD
To test if high-flow conditioned oxygen therapy is noninferior to NIV for preventing postextubation respiratory failure and reintubation in patients with hypercapnic COPD, investigators plan to conduct the participants level, 1:1…
- Trial name
- COPD (NCT03928535)
- Testing
- High-FlowNasal Cannula, Noninvasive Ventilation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xiangya Hospital of Central South University
Healthy Volunteers
Physiological Effects of High-flow Nasal Cannula During Exercise
The high-flow nasal cannula (HFNC) has increased its evidence in patients during pulmonary rehabilitation. These studies hypothesize that the physiological effects of HFNC (positive expiratory pressure, anatomical dead space…
- Trial name
- NCT05550935
- Testing
- High-flow Nasal Cannula
- Where
- Chile
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Respiratory Distress Syndrome
Effect of High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure
Respiratory distress syndrome (RDS) in preterm babies is caused by a deficiency of lung surfactant. The risk of RDS increases with decreasing gestational age, and is almost inevitable in babies born at less than 28 weeks…
- Trial name
- NCT05849116
- Volunteers
- 100 people
- Sponsor
- Assiut University
Respiration, Artificial
A SBT-based Protocol-directed Program in Difficult-to-Wean Patients
Weaning patients from a ventilator is one of the most challenging processes in an intensive care unit. The investigators aimed to determine whether spontaneous breathing trial (SBT)-based protocol-directed weaning combined with…
- Trial name
- NCT05035355
- Testing
- a weaning protocol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- JinyanXing
Postoperative Hypoxemia
Transoral Nasal Cannula Oxygen Therapy for Mouth-Breathing Patients in the Postanesthesia Care Unit
Postoperative hypoxemia is a common complication in the postanesthesia care unit (PACU). Patients who breathe through the mouth after tracheal extubation may receive limited benefit from standard nasal cannula oxygen therapy…
- Trial name
- NCT07841223
- Testing
- Transoral nasal cannula oxygen delivery
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University