Clinical trials: Nasal Surgical Procedures
Nasal Surgery, Anesthesia
Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery
This study compares remifentanil infusion versus nicardipine infusion for controlled hypotension during elective nasal surgery. Both agents are standard clinical methods.
- Conditions
- Nasal Surgery, Anesthesia, Controlled Hypotension for Nasal Surgeries
- Trial name
- NCT07660562
- Testing
- Nicardipine, Remifentanil
- Volunteers
- 44 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Airway Complication of Anesthesia
Role of Airway Topicalization in Awake Fiberoptic Intubation
Airway management is an integral part of general anesthesia. Difficult airway management may lead to various adverse events such as airway trauma, up to cardiopulmonary arrest.
- Trial name
- NCT06720220
- Testing
- Dexmedetomidine Hydrochloride, Nebulization, Atomization
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Colonoscopy, Positive-Pressure Respiration
Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center
The primary objective of the prospective study is to compare the incidence, duration, and severity of oxygen desaturation in high-risk patients randomized to nasal mask with nasal positive airway pressure (PAP) or standard care…
- Trial name
- NCT05754255
- Testing
- Nasal Cannula, Nasal Positive Airway Pressure System
- Where
- United States
- Sponsor
- Indiana University
COVID 19, SARS-Cov-2
Combination of Chest Scanography and Nasal Viral Detection Test to Detect COVID-19 Positive Patients Before Surgical Intervention in a University Hospital During Coronavirus Pandemia
This research aims to improve the screening for COVID-19 upon admission to the Montpellier University Hospital for an act under general anesthesia or at high risk of transmission of the virus.
- Trial name
- COVID-Scan (NCT04355715)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Septal Deformity, Nasal Obstruction
A Clinical Study to Evaluate the Safety and Efficacy of Surgical Material for Nasal Septoplasty
The purpose of this clinical trial is to evaluate safety and efficacy of TnR mesh for patients who need nasal septoplasty for septal deformity with nasal obstruction.
- Trial name
- NCT03088618
- Testing
- Nasal septoplasty
- Where
- 2 sites in South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- T&R Biofab Co., Ltd.
Septoplasty
Different Techniques for Prevention of Complications After Septoplasty Operation
the aim of the study is to compare complication of trans-nasal quilting sutures, nasal pack and intra intranasal silicon splint in endoscopic septoplasty
- Trial name
- NCT06920368
- Testing
- septoplasty with nasal packs, septoplasty with intra-nasal silicon splint, septoplasty with trans--septal quilting sutures
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Surgical Wound Infection, Preoperative Care
Povidone-Iodine for Nasal Decolonization
To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA.
- Conditions
- Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
- Trial name
- NCT05529173
- Testing
- Povidone-Iodine 10%, 0.9% NaCl Solution
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
Rhinosinusitis, Sinusitis
Clinical Outcomes and Patient Satisfaction With Velnez Versus Nasopore in Nasal Surgery
This clinical trial evaluated two absorbable nasal packing materials - VELNEZ and NASOPORE - in adult patients (18-70 years) who underwent nasal surgery, including septoplasty, FESS, or turbinoplasty.
- Conditions
- Rhinosinusitis, Sinusitis, Chronic Rhino-sinusitis
- Trial name
- NCT07560254
- Testing
- VELNEZ Nasal Pack, NASOPORE Nasal Pack
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- Ayu, Inc.
Laryngoscopy, Child
Airway Interventions During Intravenous Anesthesia in Children Undergoing Direct Laryngoscopy for Surgical Procedures Using High Flow Nasal Versus Low Flow Oxygen. A Pilot Study.(Flowkid)
The goal of this clinical trial is to evaluate possible differences in airway responses and interventions during intravenous anesthesia for direct laryngoscopy in children when comparing two oxygenation methods (conventional low…
- Conditions
- Laryngoscopy, Child, Oxygen Therapy
- Trial name
- NCT06037915
- Testing
- low flow oxygen with nasopharyngeal tube, high flow oxygen with OptiflowTM Nasal High Flow
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Laryngologic Surgical Procedures
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery
The purpose of this study is to investigate whether selected, short laryngologic surgical procedures can be safely and potentially more effectively performed without the use of endotracheal tube or jet ventilation, under…
- Trial name
- NCT03091179
- Testing
- THRIVE, Endotracheal tube
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Surgical Site Infection
Prevention of Surgical Site Infections: Effectiveness of Nasal Povidone-Iodine and Nasal Mupirocin
We hypothesize the application of mupirocin or povidone-iodine to the nares is equally effective in short term Staphylococcus aureus(SA)suppression.
- Trial name
- NCT01313182
- Testing
- mupirocin calcium ointment, 2%, 3M Skin and Nasal Antiseptic
- Where
- United States
- Volunteers
- 1,874 people
- Sponsor
- Solventum US LLC
Nose Diseases
Pre-emptive Analgesia Using Nebulized Ketamine Versus Nebulized Dexmedetomidine in Endoscopic Nasal Surgeries
this study aims to compare the efficacy of pre-emptive nebulized ketamine versus nebulized dexmedetomidine for post operative pain relief in endoscopic nasal surgery
- Trial name
- NCT07056582
- Testing
- Dexmedetomidine, Ketamine, 0.9%sodium chloride
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Sohag University
Postoperative Pain
Efficacy of Fentanyl Soaked Nasal Packs on Postoperative Pain in Nasal Surgeries.
Efficacy of fentanyl soaked nasal packs on postoperative pain in nasal surgeries.
- Trial name
- NCT06531759
- Testing
- Fentanyl
- Volunteers
- 100 people
- Sponsor
- Assiut University
Head and Neck Cancer
Analysis of Tumor Tissue and Lymph Nodes Surgically Removed From Patients With Cancers of the Head and Neck
RATIONALE: Diagnostic procedures, such as analysis of tumor tissue and lymph nodes that have been surgically removed, may improve the treatment of patients with cancers of the head and neck.
- Trial name
- NCT00002695
- Testing
- DNA stability analysis, microsatellite instability analysis, mutation analysis
- Where
- 4 sites in United States
- Volunteers
- 530 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Hypotension During Surgery
Controlled Hypotension in Rhinoplasty and Septoplasty: Incidence of Cognitive Dysfunction and Delirium
Controlled hypotension application is a commonly preferred anesthesia practice during surgical procedures, particularly in regions with rich tissue perfusion, aiming to reduce bleeding, enhance surgical field visibility, and…
- Trial name
- NCT06238973
- Testing
- Group Low, Group Middle
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University
Idiopathic Rhinitis
Posterior Nasal Nerve Combined With Anterior Ethmoid Neurotomy for Idiopathic Rhinitis
The present study was a prospective, parallel controlled, multicentre clinical study. The trial was divided into two groups, the posterior nasal nerve combined with anterior ethmoid neurotomy group (group A) and the standardized…
- Trial name
- NCT06870292
- Testing
- Posterior nasal nerve combined with anterior ethmoid neurotomy, Drug therapy group
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- Xu Yu
Staphylococcus Aureus
Evaluation of a Diagnostic Device for Detection of Nasal Staphylococcus Aureus
To establish the clinical test performance characteristics of sensitivity, specificity and predictive values for direct detection of nasal Staphylococcus aureus colonization against clinical microbiology laboratory culture…
- Trial name
- NCT00406549
- Where
- 11 sites in United States, France and 2 more
- Volunteers
- 2,000 people
- Sponsor
- Solventum US LLC