Clinical trials: Nasolabial Fold
Nasolabial Folds, Wrinkles
TEOSYAL® RHA Ultra Deep and Perlane-L® for the Correction of Nasolabial Folds
The purpose of this study is to compare the effectiveness and safety of TEOSYAL® RHA Ultra Deep versus Perlane-L® in the treatment of moderate to severe nasolabial folds.
- Trial name
- NCT02253147
- Testing
- TEOSYAL® RHA Ultra Deep
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Teoxane SA
Granulomatous Disorder
Protocol for the Post-approval Study of Artefill for Correction of Nasolabial Folds
This study is a five-year, multi-center, non-randomized, non-controlled post-approval study designed to follow a total of 1000 consecutive qualified and consenting subjects treated with ArteFill® in the course of clinical…
- Trial name
- NCT03299712
- Testing
- ArteFill
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Suneva Medical, Inc.
Nasolabial Folds
Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose
Safety study that compares Perlane to Perlane with Lidocaine while correcting wrinkles in the area around your nose.
- Trial name
- NCT00823069
- Testing
- Perlane and Perlane-L
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medicis Global Service Corporation
Dermatological Non-Disease
Effectiveness and Safety of Princess FILLER Lidocaine in Correction of Nasolabial Folds (NLF)
Clinical Investigation to demonstrate the effectiveness and safety of Princess Filler Lidocaine in the correction of moderate to severe nasolabial folds
- Trial name
- FILIDO (NCT03990883)
- Testing
- Princess Filler Lidocaine
- Where
- 11 sites in United States
- Volunteers
- 295 people
- Sponsor
- Croma-Pharma GmbH
Nasolabial Folds, Wrinkles
A Prospective Clinical Investigation of DMFI150 for Treating Nasolabial Folds
This is a prospective clinical investigation designed to evaluate the performance and safety of DMFI150 for the treatment of nasolabial folds. 30 adult participants will receive a single treatment with the investigational device.
- Trial name
- NCT07292779
- Testing
- DMFI150
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Nasolabial Fold, Hypoplastic
Safety Study of TPX-121 on Nasolabial Folds
Nasolabial folds augmentation is possible through dermal filler and botulinum toxin, however, safety issues are existed as well as efficacy. Therefore, there is a need for a safer procedure for nasolabial folds correction.
- Trial name
- NCT06533540
- Testing
- TPX-115(allogeneic fibroblasts)
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Tego Science, Inc.
Wrinkles
A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Volume Plus Versus YVOIRE Volume in Nasolabial Fold Injection
The objective of this study was to evaluate the efficacy and safety of HA IDF II plus (with lidocaine) injected in the nasolabial fold compared to HA IDF II (without lidocaine).
- Trial name
- NCT02340078
- Testing
- HA IDF II plus, HA IDF II
- Volunteers
- 62 people
- Sponsor
- LG Life Sciences
Facial Wrinkles
A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)
The purpose of this research study is to compare subject comfort during and after injection with NADGL and Captique® Injectable Gel, in the nasolabial folds.
- Trial name
- NCT00417469
- Testing
- NADGL
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Genzyme, a Sanofi Company
Aging
Split-face Comparison Study to Assess ELAPR Compared to Juvéderm® for the Treatment of Nasolabial Folds
Patients presenting to the clinic for treatment of moderate to severe Nasolabial folds will be recruited to receive either ELAPR002b or ELAPR002d for the treatment of one Nasolabial fold and Juvéderm® Ultra Plus for the treatment…
- Trial name
- NCT01463657
- Testing
- Juvéderm® Ultra Plus, ELAPR002
- Where
- 2 sites in Australia
- Volunteers
- 30 people
- Sponsor
- Elastagen Pty Ltd
Lips Enhancement, Perioral Wrinkles
Evaluation of Facial HA Dermal Fillers in Real-Life Conditions
The goal of this post-market interventional study is to confirm, under real-life conditions, the safety and performance of hyaluronic acid-based dermal fillers intended to modify skin anatomy and facial appearance.
- Conditions
- Lips Enhancement, Perioral Wrinkles, Nasolabial Fold Wrinkles, Cheek Augmentation
- Trial name
- NCT07255261
- Testing
- Facial injection of hyaluronic acid-based dermal fillers.
- Where
- 8 sites in France
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Symatese
Nasolabial Folds
Evaluation of Pain With Radiesse® With Lidocaine for Nasolabial Folds
To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler with lidocaine
- Trial name
- NCT01069354
- Testing
- Radiesse® Injectable Dermal Filler with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Where
- 2 sites in Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Correction of Nasolabial Folds
A Clinical Investigation of the Decoria® Aesthetic Group (DAG) for Correction of Nasolabial Folds (NLF)
Decoria intense is a class III medical device and is CE-marked and has been on the market since 2014. Decoria intense is a hyaluronic acid filler that will be used according to intended use for correction of nasolabial folds.
- Trial name
- Decorate01 (NCT05235126)
- Testing
- Decoria intense
- Where
- 2 sites in Sweden
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Bohus Biotech AB
Correction of Nasolabial Folds
Post Market Study Evaluating Princess Filler Lidocaine for the Correction of Nasolabial Folds
In this study, eligible subjects with moderate to severe nasolabial folds will be treated with Princess® FILLER Lidocaine and will return for follow-up assessments 2, 4, 24 and 36 weeks after the treatment.
- Trial name
- FINO (NCT03611491)
- Testing
- Princess FILLER Lidocaine
- Where
- 2 sites in Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Lips Enhancement Nasolabial Fold Correction Midface Volume Deficit
THE EVALUATION OF THE SAFETY AND PERFORMANCE OF AN INJECTABLE HYALURONIC ACID FILLER
Evaluation of the safety and performance of the investigational device in its three concentrations for cheek and lips augmentation and correction of the nasolabial folds, assuming that the performance of the product will be…
- Trial name
- NCT07763990
- Testing
- HLR-1, HLR-2, HLR-3
- Where
- 2 sites in Israel
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Hallura Ltd.
Correction of Nasolabial Folds
Clinical Study to Evaluate the Efficacy and Safety of Dermalax Implant Plus
This study is to verify that Dermalax Implant Plus is not inferior to the reference device, Restylane® Sub-Q, in terms of efficacy and safety in the correction of nasolabial folds
- Trial name
- NCT02179606
- Testing
- Dermalax Implant Plus, Restylane Sub-Q
- Where
- 2 sites in South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Across Co., Ltd.
Moderate to Severe Nasolabial Folds
Saypha® Volume LIdocaine in Nasolabial Folds
Comparison of saypha Volume Lidocaine from 2 different manufacturing locations in correcting moderate to sever nasolabial folds
- Trial name
- SAVINO (NCT04883632)
- Testing
- Saypha Volume Lidocaine
- Where
- 3 sites in Austria
- Volunteers
- 110 people
- Sponsor
- Croma-Pharma GmbH
Nasolabial Folds
Belotero Post Approval Study
A prospective, open-label 1-month post-approval study to evaluate the short term safety of Belotero® Balance in the re-treatment of nasolabial folds.
- Trial name
- NCT01635855
- Testing
- Belotero®
- Where
- 9 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Facial Wrinkles
Multicenter Study of the Safety and Efficacy of Dermal Filler, Belotero® Soft
This study is to determine the safety and effectiveness of Belotero® Soft compared to active comparator in the correction of mild facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00877279
- Testing
- CosmoDerm1, Belotero Soft
- Where
- 5 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Nasolabial Folds, Wrinkles
Non-comparative Evaluation of Facial Expressions Following Lower Face Correction Using Emervel Classic and Emervel Deep
Study is designed to characterize subject and treating investigator reported outcomes in the early post-treatment period, following bilateral correction of nasolabial folds using Emervel Classic and Emervel Deep. 1.
- Trial name
- NCT02672644
- Testing
- Emervel Classic, Emervel Deep
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Folds
Evaluation of Pain With Lidocaine-Mixed Radiesse® Injectable Dermal Filler
To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler mixed with lidocaine.
- Trial name
- NCT01012661
- Testing
- Radiesse® Injectable Dermal Filler Mixed with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.