Clinical trials: Nasolabial Fold
Facial Wrinkles
Safety and Effectiveness of Belotero® in Subjects With Fitzpatrick Phototypes IV Through VI
This is a study to assess how safe and effective an investigational product, Belotero® is in people with all skin types with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00922623
- Testing
- Belotero®
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- Merz North America, Inc.
Nasolabial Fold Correction
A Study in Adults Evaluating Polycaprolactone Microsphere Filler for Treatment of Moderate to Severe Nasolabial Folds
The goal of this clinical trial is to evaluate the safety and efficacy of polycaprolactone microsphere filler (Lafullen) for the correction of moderate to severe nasolabial folds in adults aged 18 and above, regardless of gender.
- Trial name
- NCT06961448
- Testing
- Hyaluronate Gel for Injection, Polycaprolactone microsphere filler
- Volunteers
- 208 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Correction of Nasolabial Folds
Safety and Effectiveness of THIODERM STRONG in the Correction of Nasolabial Folds
This is a prospective, open label, dose-escalating, multicenter clinical investigation to evaluate the safety and effectiveness of THIODERM STRONG in the correction of nasolabial folds.
- Trial name
- NCT03650218
- Testing
- THIODERM STRONG
- Where
- 2 sites in Austria
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Dermal Filler, Hyaluronic Acid
China Post-Market Clinical Follow-up of FACILLE®
The results showed that subjects tolerated the Sodium Hyaluronate Gel for Injection (FACILLE®) well, with no systemic AEs, SAEs, and unanticipated AEs and associated with high satisfaction and self-evaluated effectiveness.
- Conditions
- Dermal Filler, Hyaluronic Acid, Nasolabial Fold
- Trial name
- NCT05294562
- Volunteers
- 1,552 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Lips Enhancement, Nasolabial Fold Correction
Evaluation of the Safety and Performance of an Injectable Hyaluronic Acid Filler
Evaluation of the safety and performance of the investigational device in its three concentrations for cheek and lips augmentation and correction of the nasolabial folds, assuming that the performance of the product will be…
- Conditions
- Lips Enhancement, Nasolabial Fold Correction, Midface Volume Deficit
- Trial name
- NCT04971876
- Testing
- HLR-1, HLR-2, HLR-3
- Where
- 3 sites in Germany, Poland
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hallura Ltd.
Nasolabial Folds
An Efficacy and Safety Study of TheraFill® Versus KOKEN for 3 Months on Nasolabial Folds
Investigational Device : TheraFill® (Atelocollagen Dermal Filler) Title : A Randomized, Multicenter, Prospective and Paired Comparison of the Efficacy and Safety of TheraFill® versus KOKEN for 3months on Nasolabial Folds Sites…
- Trial name
- NCT01060943
- Testing
- KOKEN, Atelocollagen Filler
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Physiological Stress, Disorder of Aging
Non-inferiority of Belotero® Basic Versus Juvéderm® Ultra 3
This study will investigate the non-inferiority of Belotero® Basic versus Juvéderm® Ultra 3 in the treatment of nasolabial folds
- Conditions
- Physiological Stress, Disorder of Aging, Skin Diseases, Wrinkles
- Trial name
- NCT01305187
- Testing
- Hyaluronic Acid Filler
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Nasolabial Folds
A Study Comparing SYB PDO Thread and MINT Lift® for Temporary Nasolabial Fold Improvement
The objective of this clinical trial is to verify the safety and efficacy of SYB PDO Thread in the temporary improvement of nasolabial Folds.
- Trial name
- NCT06093321
- Testing
- SYB PDO Thread, MINT lift®
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Nasolabial Folds, Wrinkles
Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds
Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds
- Trial name
- NCT07412392
- Testing
- DIOSHA S Lido, YOUTHFILL Fine with Lidocaine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hyundae Meditech
Aging, Skin Wrinkling
Safety and Effectiveness of STYLAGE® L for Correction of Moderate and Severe Nasolabial Folds in Chinese Adults
This is a safety and efficacy study of STYLAGE® Lin Chinese adults with Nasolabial Folds.
- Trial name
- NCT04861766
- Testing
- STYLAGE® L, Active Comparator
- Where
- 8 sites in China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Rhytids
A Study to Determine How Long Restylane® Will Last After Initial Treatment With 2 Different Re-treatment Schedules.
A total of 75 subjects will be enrolled into a 36 month study. Subjects will be treated with Restylane® on both sides of the face (nasolabial folds) at the first visit, on one side of the face at month 4.5 and on the other side…
- Trial name
- NCT00765583
- Testing
- Restylane
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Medicis Aesthetics, Inc.
Nasolabial Folds
Study to Assess Adverse Events and How Effective NOA LIFT is Compared to JUVÉDERM VOLIFT With Lidocaine for the Correction of Nasolabial Folds in Adults
Nasolabial folds (NLFs) are wrinkles that run from the sides of the nose to the corners of the mouth. The goal of this study is to evaluate how safe and effective NOA LIFT is compared to JUVÉDERM VOLIFT with Lidocaine for…
- Trial name
- NCT07794878
- Testing
- NOA LIFT, JUVÉDERM VOLIFT with Lidocaine
- Where
- 6 sites in China
- Volunteers
- 288 people
- Sponsor
- AbbVie
Wrinkle Severity Rating Scale(WSRS) Grade 3 (Moderate) or 4 (Severe) of Nasolabial Folds
Clinical Trial of YYD701-2 for Treatment of Nasolabial Folds
A multicenter, active-controlled, randomized, evaluator and subject blinded, split-face, comparative, non-inferiority, Medical device Clinical trial.
- Trial name
- NCT03170050
- Testing
- YYD701-2, Restylane Perlane Lidocaine
- Where
- 2 sites in South Korea
- Volunteers
- 107 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Correction of Nasolabial Folds
Observational Study to Evaluate Long-term Safety and Biodegradability of YVOIRE Volume s
To evaluate long-term safety of YVOIRE volume s by incidence of adverse events including injection site local reactions and biodegradability.
- Trial name
- NCT02661737
- Testing
- YVOIRE volume s
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Facial Wrinkles
Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.
This was a study to find out how an investigational product, Belotero, compares to a second product in people with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00876265
- Testing
- Belotero, Zyplast
- Where
- 6 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Aging
Effectiveness and Safety of STYLAGE® L Lidocaïne in the Treatment of Nasolabial Folds
STYLAGE® L Lidocaine is a CE-marked hyaluronic acid gel intended to fill skin depressions on the face by dermal injection. In this study, 50 healthy subjects between the age of 30 and 65, with moderate to severe nasolabial folds…
- Trial name
- NICE (NCT04844216)
- Testing
- STYLAGE® L Lidocaine, Active control
- Where
- 2 sites in France, Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Nasolabial Fold
Efficacy and Safety Evaluation Study of Neuramis® Deep Lidocaine in Correction of Nasolabial Fold
The purpose of this study is to compare the efficacy and safety of the study medical device, Neuramis® Deep Lidocaine and the control medical device, Restylane® PERLANE-L in correction of nasolabial folds
- Trial name
- NCT02751034
- Testing
- Neuramis® Deep Lidocaine, Restylane® PERLANE-L
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Medy-Tox
Nasolabial Fold Correction
Study to Evaluate Safety and Efficacy of Revanesse® Ultra + vs Revanesse® Ultra for Correction of NLF
A Multicenter, Double-Blind, Randomized, Split-Face Study to Evaluate the Safety and Efficacy of Revanesse® Ultra + (with Lidocaine) versus Revanesse® Ultra for the Correction of Nasolabial Folds to compare the safety and…
- Trial name
- NCT02991040
- Testing
- Revanesse Ultra+ (with lidocaine), Revanesse Ultra
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prollenium Medical Technologies Inc.