Clinical trials: Nasolabial Folds
Wrinkles, Folds
A Clinical Investigation Comparing the Safety and Performance of RefillHA Solid With Hydryalix Ultra Deep Lidocaine for the Correction of Moderate-to-severe Nasolabial Folds
Prospective, controlled, randomized, monocentric, double-blind, split-face non-inferiority clinical study to evaluate the safety and performance of injectable implant based on hyaluronic acid hydrogel with lidocaine for…
- Trial name
- NCT07736703
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glyance
Correction of Nasolabial Folds
Observational Study to Evaluate Long-term Safety and Biodegradability of YVOIRE Volume s
To evaluate long-term safety of YVOIRE volume s by incidence of adverse events including injection site local reactions and biodegradability.
- Trial name
- NCT02661737
- Testing
- YVOIRE volume s
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Nasolabial Fold, Safety
A Study to Evaluate the Performance and Safety of GP0045 for Correction of Moderate to Severe Nasolabial Folds
This is a study to assess the performance and safety of GP0045 when injected in the nasolabial folds. There is an 18 months follow up period.
- Trial name
- NCT03300466
- Testing
- GP0045, Comparator
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Folds, Marionette Lines
Emervel for the Correction of Lower Face Wrinkles & Folds
This study is designed to 1. evaluate the naturalness of facial expressions in motion (2D video images), by treating investigator assessment 2.
- Conditions
- Nasolabial Folds, Marionette Lines, Wrinkles
- Trial name
- NCT02718040
- Testing
- Emervel Classic and/or Deep Treatment Group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Fold
Efficacy and Safety Evaluation Study of Neuramis® Deep Lidocaine in Correction of Nasolabial Fold
The purpose of this study is to compare the efficacy and safety of the study medical device, Neuramis® Deep Lidocaine and the control medical device, Restylane® PERLANE-L in correction of nasolabial folds
- Trial name
- NCT02751034
- Testing
- Neuramis® Deep Lidocaine, Restylane® PERLANE-L
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Medy-Tox
Nasolabial Folds, Wrinkles
A Prospective Clinical Investigation of DMFI150 for Treating Nasolabial Folds
This is a prospective clinical investigation designed to evaluate the performance and safety of DMFI150 for the treatment of nasolabial folds. 30 adult participants will receive a single treatment with the investigational device.
- Trial name
- NCT07292779
- Testing
- DMFI150
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Aesthetics
Long Term Safety and Efficacy Assessment of Hyaluronic Acid Dermal Filler With for the Treatment of Nasolabial Folds
This study evaluates the injection of a hyaluronic acid dermal filler with lidocaine 0.3% in the treatment of nasolabial folds (NLF).
- Trial name
- ECLAH (NCT02703740)
- Testing
- Hyaluronic acid dermal filler with lidocaine 0.3%
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laboratoires Genévrier
Nasolabial Folds
Safety and Effectiveness of ELLANSÉ®-S Dermal Filler in the Treatment of Nasolabial Folds
The study will be a prospective, randomized, multi-center, split-face, controlled, double-blind clinical trial to evaluate the safety and effectiveness of ELLANSÉ®-S for the treatment of NLFs.
- Trial name
- NCT06984835
- Testing
- Ellanse S, Calcium Hydroxylapatite-based filler
- Where
- 7 sites in United States
- Volunteers
- 126 people
- Sponsor
- AQTIS Medical B.V.
Nasolabial Folds
Safety & Tolerability Study That Compares Restylane to Restylane With Lidocaine While Correcting Wrinkles in the Nasolabial Folds
Safety \& tolerability study that compares Restylane to Restylane with Lidocaine (Restylane-L) while correcting wrinkles in the area around your nose.
- Trial name
- NCT00797459
- Testing
- Restylane and Restylane-L
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medicis Global Service Corporation
Nasolabial Fold Wrinkles
CelluJuve® for the Treatment of Moderate to Severe NLFs
Single-center, open-label proof of concept study assessing the safety and effectiveness of CelluJuve® for the treatment of moderate to severe NLFs
- Trial name
- NCT07545980
- Testing
- CelluJuve®
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Spiderwort Biotechnologies Inc.
Nasolabial Folds Correction, Pain
Safety and Efficacy Study of Lidocaine Mixed Hyaluronate on Nasolabial Folds Correction
This clinical trial is a double-blind, randomized, within-subject controlled, 2-armed, single-center study sponsored by SciVision Biotech Inc. and approved by National Taiwan University Hospital Research Ethics Committee.
- Trial name
- NCT02006173
- Testing
- Lidocaine, Normal Saline
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Nasolabial Fold
Efficacy and Safety Study of Neuramis in Correction of Nasolabial Fold
This study design is a randomized, multi-center, double Masked, matched Pairs, active-controlled clinical trial. Subjects who voluntarily signed the informed consent and are judged to be eligible for this study will be…
- Trial name
- NCT01585220
- Testing
- HA filler
- Where
- 2 sites in South Korea
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Medy-Tox
Facial Rhytides, Crow's Feet Lines
Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)
A study to evaluate patient satisfaction, aesthetic and psychological impact of combined treatment with BOTOX® Cosmetic (onabotulinumtoxinA), JUVÉDERM® ULTRA XC, JUVÉDERM® ULTRA PLUS XC, JUVÉDERM® VOLUMA® XC, and LATISSE®…
- Conditions
- Facial Rhytides, Crow's Feet Lines, Glabellar Lines, Nasolabial Fold
- Trial name
- NCT02176356
- Testing
- onabotulinumtoxinA, bimatoprost ophthalmic solution 0.03%, JUVÉDERM® ULTRA XC
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Allergan
Wrinkles
Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolabial Folds
The purpose of this study was to assess the safety and efficacy of a new metallic cannula to inject hyaluronic acid for dermal augmentation in the nasolabial folds compared to standard needle.
- Trial name
- NCT01066026
- Testing
- hyaluronic acid with metallic cannula or standard needle., Hyaluronic acid injected with the new tool.
- Where
- 2 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Nasolabial Folds
Hyaluronic Acid Filler IMD1 Basic for Correction of Nasolabial Folds
Volunteers receive one injection IMD1 basic of correction of nasolabial folds and are followed-up for up to 36 weeks.
- Trial name
- NCT00429520
- Testing
- Hyaluronic acid filler/IMD1 basic
- Where
- Germany
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Nasolabial Folds
A Study to Confirm Safety and Effectiveness of RADIESSE® Injectable Implant for the Correction of Moderate to Severe Nasolabial Folds
The purpose of this study is to confirm the long-term safety, effectiveness, and degradation profile of RADIESSE® Injectable Implant for the correction of moderate to severe nasolabial folds (NLFs) in Chinese adults.
- Trial name
- Radiesse China (NCT07856797)
- Testing
- Subdermal Implant
- Volunteers
- 163 people
- Sponsor
- Merz North America, Inc.
Wrinkles
A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Volume Plus Versus YVOIRE Volume in Nasolabial Fold Injection
The objective of this study was to evaluate the efficacy and safety of HA IDF II plus (with lidocaine) injected in the nasolabial fold compared to HA IDF II (without lidocaine).
- Trial name
- NCT02340078
- Testing
- HA IDF II plus, HA IDF II
- Volunteers
- 62 people
- Sponsor
- LG Life Sciences
Nasolabial Folds
Efficacy and Safety of a 'Graft/Prosthesis, Biomaterial (DKM410)' in the Treatment of Both Nasolabial Folds
The purpose of the study is to assess the efficacy and safety of a 'Graft/prosthesis, biomaterial (DKM410)' in the treatment of both nasolabial folds.
- Trial name
- NCT05612958
- Testing
- DKM-410, Juvederm ULTRA PLUS XC 1.0ml
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Dongkook Pharmaceutical Co., Ltd.
Nasolabial Folds
Extension Study for 43USSA1705
To evaluate the long-term safety of Sculptra Aesthetic as a single regimen for correction of Nasolabial Fold (NLF) contour deficiencies after changes in reconstitution and injection procedures compared to the approved label.
- Trial name
- NCT04225273
- Testing
- Sculptra Aesthetic, Lidocaine HCL
- Where
- 4 sites in United States
- Volunteers
- 38 people
- Sponsor
- Galderma R&D
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.