Clinical trials: Nausea, open to volunteers
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Hyperemesis Gravidarum
Hyperemesis Gravidarum Risk Reduction With Metformin
The goal of this clinical trial is to evaluate whether daily oral metformin extended-release (metformin-XR), taken prior to and in early pregnancy, can reduce the risk and severity of Hyperemesis Gravidarum (HG), a severe nausea…
- Trial name
- NCT07129473
- Testing
- Metformin Extended Release Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Nausea and Vomiting
The Safety and Effectiveness of Palonosetron Hydrochloride Capsule Was Used to CINV
To observe and evaluate the safety and effectiveness of Palonosetron hydrochloride capsule in preventing acute nausea and vomiting caused by moderate emetic chemotherapy; The characteristics of the applicable population, clinical…
- Trial name
- TSEPHCC (NCT05690802)
- Testing
- Palonosetron hydrochloride capsules
- Where
- China
- Volunteers
- 1,060 people
- Sponsor
- Xijing Hospital
Chronic Nausea
Vagal Auricular Stimulation for Motion Sickness
This study aims to understand the mechanisms underlying nausea response in the brain stem, and the effect of vagal nerve stimulation on nausea.
- Trial name
- VAMOS (NCT07873164)
- Testing
- UROStim
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Patient With Indication for Major Abdominal Submesocolic, Parietal, Left Pancreatic or Liver Surger
Evaluation of the Value of Ultrasound Measurement of Stomach Diameter in Predicting Postoperative Nausea/Vomiting
The advent of enhanced rehabilitation after surgery has helped to reduce surgical stress, thereby improving postoperative outcomes by reducing the time it takes for patients to recover their transit and autonomy.
- Trial name
- EVOL2 (NCT07063069)
- Testing
- Abdominal ultrasound
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Laparoscopic Cholecystectomy
Binaural Beats and Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy
This research is a single-center, parallel-group, single-blind, randomized controlled experimental study planned to evaluate the effect of postoperative binaural beats (BB) application on the incidence of postoperative nausea and…
- Trial name
- NCT07879274
- Testing
- Binaural Beats Application
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Bitlis Eren University
Electroacupuncture, Olanzapine-contained Four-drug Antiemetic
Electroacupuncture Plus Antiemetic Therapy for Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer
This study explores the effectiveness of combining electroacupuncture with olanzapine-containing four-drug antiemetic therapy to mitigate chemotherapy-induced nausea and vomiting (CINV) in patients with breast cancer.
- Conditions
- Electroacupuncture, Olanzapine-contained Four-drug Antiemetic, Nausea and Vomiting
- Trial name
- NCT06314906
- Testing
- Electroacupuncture, Antiemetic Therapy
- Where
- China
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Feixue Song
Postoperative Nausea and Vomiting, Bariatric Sleeve Gastrectomy
Use of Transcutaneous Electrical Nerve Stimulation Device, Reletex Reliefband, With Current ERAS (Enhanced Recovery After Surgery) Protocol to Further Decrease Postoperative Nausea and Vomiting in the Bariatric Surgical Patient Within the First 24 Hours Postoperatively.
The goal of this clinical trial is to learn if the Reletex Reliefband device when used in conjunction with our current treatments will further decrease postoperative nausea and vomiting.
- Trial name
- NCT07063979
- Testing
- Wearable Transcutaneous electrical Nerve Stimulation unit to mitigate postoperative nausea and vomiting (PONV) in the Bariatric Surgical Patient
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Postoperative Nausea and Vomiting, Postoperative Pain After Laparoscopic Sleeve Gastrectomy
Paragastric Block for Pain and PONV in Sleeve Gastrectomy
This single-center, prospective, randomized, double-blind controlled trial aims to evaluate the effects of intraoperative paragastric block (PGBLOCK) on early postoperative visceral pain, postoperative nausea and vomiting (PONV)…
- Trial name
- BLOCK-SG (NCT07274215)
- Testing
- Bupivacaine 0.5%, Isotonic Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital
Postoperative Nausea and Vomiting (PONV)
Granisetron Combined With Dexamethasone or Metoclopramide for PONV Prevention After Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV) remain common and distressing complications following laparoscopic cholecystectomy, particularly in female patients.
- Trial name
- NCT07360431
- Testing
- Granisetron
- Volunteers
- 102 people
- Sponsor
- Assiut University
Nausea and Vomiting, Postoperative, Cesarean Delivery
Frequency of Occurrence and Risk Factors of Postoperative Nausea and Vomiting During Elective C-section Under Spinal Anesthesia With Preventive Medication
The aim of this study is to learn about the incidence and risk factors of nausea and vomiting during planned caesarean section under spinal anesthesia.
- Conditions
- Nausea and Vomiting, Postoperative, Cesarean Delivery, Spinal Anesthesia, Antiemetic Therapy
- Trial name
- NCT06927830
- Where
- 2 sites in Belgium
- Volunteers
- 400 people
- Sponsor
- University of Liege
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Hematologic Neoplasms, Nausea
The Effect of a Protective Oral Care Protocol Using Peppermint Oil Mouthwash
Hematologic malignancies are the fifth most common type of cancer in the world. Patients with hematologic malignancies receive long-term and exhausting treatments such as chemotherapy, radiotherapy, hematopoietic stem cell…
- Conditions
- Hematologic Neoplasms, Nausea, Vomiting, Anorexia
- Trial name
- NCT07179094
- Testing
- Routine Protective Oral Care, Protective Oral Care Using Peppermint Oil Mouthwash
- Volunteers
- 72 people
- Sponsor
- Şule Güzle
Pediatric Migraine
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
- Trial name
- NCT04649242
- Testing
- Rimegepant/BHV3000
- Where
- 246 sites in United States, Canada and 7 more
- Volunteers
- 2,100 people
- Sponsor
- Pfizer
Visceral Pain, Analgesia
Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy
This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid).
- Conditions
- Visceral Pain, Analgesia, Opioid Use, Postoperative Nausea
- Trial name
- ANB (NCT06753500)
- Testing
- Autonomic neural blockade
- Where
- 2 sites in Colombia
- Volunteers
- 60 people
- Sponsor
- Universidad Simón Bolívar
Sleeve Gastrectomy
Impact of Foot Reflexology on Nausea After Obesity Surgery
Obesity is a major public health issue. The Obépi epidemiological survey, the results of which were published in 2020, shows a steady increase in obesity among the French population.
- Trial name
- IRANNO (NCT07313293)
- Testing
- Foot reflexology
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Postoperative Vomiting, Postoperative Nausea and Vomiting
Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus Surgery
Pediatric strabismus surgery is frequently followed by postoperative nausea and vomiting, which can cause significant discomfort, dehydration, and delayed recovery in young children.
- Conditions
- Postoperative Vomiting, Postoperative Nausea and Vomiting, Strabismus
- Trial name
- NCT07871292
- Testing
- Ketamine and Propofol, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting
This clinical trial tests how well aromatherapy essential oils work to manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting.
- Trial name
- NCT07126301
- Testing
- Aromatherapy and Essential Oils, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- City of Hope Medical Center
Postoperative Nausea and Vomiting
Time to First Rescue Antiemetic With Ondansetron Plus Metoclopramide Versus Dexamethasone Plus Metoclopramide for PONV Prophylaxis in Laparoscopic Cholecystectomy
The goal of this superiority randomized controlled trial (RCT) is to learn if one dual-drug arm increases patient comfort (time to needing rescue medication for nausea/vomiting) more effectively than the other in adults with…
- Trial name
- NCT07638527
- Testing
- ondansetron 4 mg, Dexamethasone (intravenous), Metoclopramide 10mg
- Where
- Pakistan
- Volunteers
- 264 people
- Sponsor
- Faisalabad Medical University
Breast Cancer
Netupitant/Palonosetron for Prevention of Nausea and Vomiting in Breast Cancer ADC Therapy
Netupitant/Palonosetron for Prevention of Nausea and Vomiting in Breast Cancer ADC Therapy
- Trial name
- NCT07918079
- Testing
- Netupitant and Palonosetron, Dexamethasone, Olanzapine 5 Mg ORAL TABLET
- Volunteers
- 84 people
- Sponsor
- Fudan University