Clinical trials: Nausea and Vomiting, Postoperative
Nausea and Vomiting Post-foregut Surgery
Reletex Versus Standard of Care Therapy for Post-Operative Nausea Control in Patients Undergoing Foregut Surgery
The effect a ReletexTM device has on postoperative nausea and vomiting when used with ondansetron after foregut surgery will be studied.
- Trial name
- Reletex (NCT01510379)
- Testing
- Reletex, IV ondansetron 4 mg q 6 hours for a total of 4 doses, IV promethazine 25 mg q 6 hours prn
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kyle A Perry
Postoperative Nausea and Vomiting, Cardiovascular Surgical Procedures
Propofol Infusion and PONV in Cardiac Surgery
The aim of this observational cohort study is to evaluate the effect of high-dose versus low-dose propofol infusion on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing coronary artery bypass…
- Trial name
- nausea vomitng (NCT07386379)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Nausea and Vomiting
Aprepitant for Postoperative Nausea and Vomiting in Laparoscopic Hysterectomy
Gynecological surgery is associated with a high incidence of postoperative nausea and vomiting. NK1 receptor antagonists such as aprepitant appear to be highly effective for treating acute and delayed emesis, and yet…
- Trial name
- NCT01440673
- Testing
- Aprepitant
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Gachon University Gil Medical Center
Inguinal Hernia
Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine
the study aimed to investigate the effect of Iv nalbuphine on postoperative nausea and vomiting and pain with intrathecal morphine on inguinal hernia repair surgery.
- Trial name
- NCT05704673
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients
This study will compare two different drug regimens (oral dronabinol versus intravenous ondanseteron) for the prevention of post-operative nausea and vomiting (PONV).
- Trial name
- PONV (NCT00757822)
- Testing
- Dronabinol, Ondansetron
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Pain, Postoperative, Tonsillar Bleeding
Dexamethasone and Postoperative Bleeding Following Tonsillectomy in Children
Tonsillectomy is one of the most frequently performed surgical interventions in children. However, it is associated with a high incidence of PostOperative Nausea and Vomiting (PONV), severe pain and haemorrhage.
- Conditions
- Pain, Postoperative, Tonsillar Bleeding, Postoperative Nausea and Vomiting
- Trial name
- Blueberry (NCT04188431)
- Testing
- Dexamethasone, Sodium chloride
- Where
- 2 sites in Canada, Switzerland
- Volunteers
- 523 people
- Sponsor
- Walid HABRE
PONV, Regional Anaesthesia
Incidence and Factors Associated With PONV in Regional Anaesthesia
Post-operative nausea and vomiting (PONV) is one of the complications associated with surgery and anaesthesia. The main aim of the study is to determine the incidence of post-operative nausea and vomiting among surgical patients…
- Trial name
- NCT03835234
- Where
- Uganda
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Makerere University
Postoperative Pain, Postoperative Nausea
IV Acetaminophen for Postoperative Analgesia
The purpose of this study is to evaluate the use of IV acetaminophen for postoperative pain management after laparoscopic cholecystectomy to determine if its use to supplement standard of care pain management decreases the…
- Conditions
- Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT01798316
- Testing
- IV Acetaminophen, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 105 people
- Sponsor
- Northwell Health
Postoperative Nausea and Vomiting
Safety of Preoperative Oral Administration of a High Caloric Drink With Protein
The purpose of the study is to determine whether the oral administration of a high caloric drink with protein decreases the postoperative nausea and vomiting in patients with dysgnathia.
- Trial name
- NCT00151099
- Testing
- high caloric drink with protein
- Where
- Germany
- Sponsor
- University Hospital Muenster
Postoperative Nausea, Adverse Effects
Safety and Tolerability of Controlled-release Oxycodone on Postoperative Pain in Oncologic Head and Neck Surgery
The hypothesis of this study is that controlled release oxycodone can be safe and well tolerated for the control of postoperative pain in surgery for head and neck cancer.
- Conditions
- Postoperative Nausea, Adverse Effects, Opioid Analgesic Adverse Reaction, Pain
- Trial name
- NCT01834898
- Testing
- Controlled-release oxycodone
- Where
- Brazil
- Volunteers
- 83 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Postoperative Nausea and Vomiting
Prevalence and Associated Factors of Post-operative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is a surgical complication defined as any nausea, and vomiting with in the first 24-48 hours after surgery in inpatients.
- Trial name
- NCT05970055
- Testing
- elective surgery
- Where
- Ethiopia
- Volunteers
- 677 people
- Sponsor
- Sara Timerga
Postoperative Nausea and Vomiting
Oral Dexamethasone for Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV) are common complications after laparoscopic cholecystectomy. This study aims to evaluate the efficacy of the administration of prophylactic oral dexamethasone at night before surgery in…
- Trial name
- NCT06288035
- Testing
- Dexamethasone Oral, Dexamethasone
- Where
- Egypt
- Volunteers
- 814 people
- Sponsor
- Mansoura University
Incidence of Postoperative Nausea and Vomiting
Comparison of the Effects of Neostigmine With Sugammadex on Postoperative Nausea and Vomiting.
Postoperative nausea and vomiting is one of most common complications after general anesthesia. Female sex, history of postoperative nausea and vomiting, motion sickness, non smoker status, opioid administration are known as risk…
- Trial name
- NCT02286752
- Testing
- Neostigmine, sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Ordu University
Caudal Anesthesia
Preventative Effect of Combining Dexamethasone with Ondansetron on Postoperative Nausea, Vomiting and Shivering in Children Undergoing Caudal Anesthesia on Hypospadias Surgery
caudal epidural block is a technique used as an adjuvant to general anesthesia for postoperative analgesia in pediatric patients,especially those with infraumbilical, perineal and lower extremity surgery , because it reduces the…
- Trial name
- NCT06747975
- Testing
- Dexamethasone and Ondansetron, Bupivacaine + saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Postoperative Nausea and Vomiting, Dexamethasone Palmitate
Dexamethasone Palmitate for PONV After Open Surgery
Dexamethasone is almost one of the most commonly used drugs for postoperative nausea and vomiting (PONV) prevention. However, PONV is still a complex problem to be solved; for example, even with preoperative dexamethasone…
- Conditions
- Postoperative Nausea and Vomiting, Dexamethasone Palmitate, Open Surgery
- Trial name
- NCT06997419
- Testing
- Dexamethasone Palmitate, Dexamethasone
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Pain, Postoperative Nausea and Vomiting
A Study to Assess Analgesic Efficacy of Intravenous Lignocaine
The primary objectives of this study are to analyse the effect of perioperative systemic infusion of lignocaine on postoperative pain, postoperative nausea and vomiting and perioperative levels of inflammatory mediators in…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Postoperative Ileus
- Trial name
- NCT01699919
- Testing
- Intravenous lignocaine
- Where
- India
- Volunteers
- 134 people
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Gynecological Disease
Optimal Haloperidol Dose for Postoperative Nausea and Vomiting Prevention in High-risk Patients
Low-dose haloperidol is known to be effective for the treatment of postoperative nausea and vomiting (PONV). However, precise dose-response studies have not been completed, especially in patients at high risk for PONV who require…
- Trial name
- NCT01639599
- Testing
- Dexamethasone iv injection, Dexamethasone, haloperidol
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Postoperative Nausea and Vomiting (PONV)
Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female Patients
The proposed randomized clinical trial aims to test and compare the efficacy of chewing gum vs. Intravenous antiemetic ondansetron as rescue treatment for post-operative nausea and vomiting (PONV) among Lebanese female patients…
- Trial name
- NCT07201883
- Testing
- Ondansetron (Zofran), chewing gum, Ondansetron + Chewing gum
- Where
- Lebanon
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Fasting
The Effects of Carbohydrate-electrolyte Solution on Metabolic Responses in Paediatric Patients
The aim of this study is to evaluate the effects of oral administration of carbohydrate-electrolyte-containing fluid, compared to standard clear fluid during preoperative fasting on metabolic responses, preoperative anxiety and…
- Trial name
- NCT05729100
- Testing
- Oral carbohydrate-electrolyte solution, Control
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia