Clinical trials: Nausea and Vomiting
Chemotherapy Induced Nausea and Vomiting, Quality of Life (QOL)
Vomiting Prevention in Children With Cancer
The goal of this single arm trial is to learn if a machine learning (ML) model predicting the risk of vomiting within the next 96 hours will impact vomiting outcomes in inpatient cancer pediatric patients.
- Conditions
- Chemotherapy Induced Nausea and Vomiting, Quality of Life (QOL), Pediatric Cancer
- Trial name
- NCT06886451
- Testing
- ML-based intervention
- Where
- Canada
- Volunteers
- 1,953 people
- Sponsor
- The Hospital for Sick Children
Anxiety, Labor Pain
Exploring the Effect of Aromatherapy
To explore the effect of aromatherapy in laboring patients with pain, anxiety, and/or nausea/vomiting.
- Conditions
- Anxiety, Labor Pain, Nausea and Vomiting
- Trial name
- NCT07155876
- Testing
- Aromatherapy plus standard of care, Standard of Care Only
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Baptist Health South Florida
Hypotension, Nausea
Granisetron Use, Blood Pressure, and Nausea and Vomiting During Cesarean Delivery Under Spinal Anesthesia
This study will observe 80 adults having a cesarean delivery under spinal anesthesia at Kayseri City Hospital. It will compare patients who receive granisetron as part of routine care to prevent nausea and vomiting with patients…
- Conditions
- Hypotension, Nausea, Vomiting, Cesarean Section
- Trial name
- NCT07861737
- Testing
- Granisetron
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kayseri City Hospital
Nausea and Vomiting, Postoperative
The Effect of Cold Steam Application on Nausea and Vomiting
The aim of this study was to determine the effect of cold vapour applied to patients undergoing laparoscopic abdominal surgery primarily on nausea and vomiting and secondarily on antiemetic requirement, patient satisfaction and…
- Trial name
- NCT06760871
- Testing
- nebulised distilled water
- Where
- Turkey (Türkiye)
- Sponsor
- Trakya University
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Pain, Nausea With Vomiting Chemotherapy-Induced
The Effect of Acupressure on Pain, Nausea-Vomiting, and Mental Well-Being in Oncology Patients
The goal of this clinical trial is to compare the effect of self acupressure and acupressure applied by therapists on pain, nausea-vomiting, and mental well-being in oncology patients.
- Conditions
- Pain, Nausea With Vomiting Chemotherapy-Induced, Mental Health Wellness 1
- Trial name
- NCT05898880
- Testing
- Self-acupressure, Acupressure by therapists, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Gastroparesis
Cardiac Vagal Effects of GES in Patients With Gastroparesis and Vagal Nerve Action Potentials in Vagus Nerve
The objective of this study is to determine if Gastric Electrical Stimulation may influence vagal outflow via vagal afferent fibers that terminate in the Central Nervous System.
- Trial name
- GES (NCT02159586)
- Testing
- gastric electrical stimulator
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Indiana University
Intraoperative Nausea-retching-vomiting Episodes, Spinal Aneshtesia
Routine Antiemetic Prophylaxis for Nonfasted Parturients Undergoing Cesarean Sections Under Spinal Anesthesia
The aim of this prospective randomized double-blind study is to compare the effectiveness of routine antiemetic prophylaxis for the prevention of intraoperative nausea and vomiting (IONV) in non-fasted parturients undergoing…
- Conditions
- Intraoperative Nausea-retching-vomiting Episodes, Spinal Aneshtesia, Ceserean Section, Antiemetic Therapy
- Trial name
- NCT07740577
- Testing
- Ondansetron 4mg, metoclopramide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sanliurfa Education and Research Hospital
Postoperative Nausea and Vomiting (PONV)
Early Postoperative Pain After Cardiac Surgery
This observational study will evaluate factors that may be associated with pain during the first 24 hours after open heart surgery.
- Trial name
- NCT07804732
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Antalya Training and Research Hospital
Postoperative Nausea and Vomiting, Postoperative Pain
Spinal Morphine and Atropine Added to General Anaesthesia for Nausea and Pain After Abdominal Laparoscopy
Laparoscopic abdominal surgery carries one of the highest risks of postoperative nausea and vomiting (PONV), and postoperative opioids given for pain are themselves emetogenic.
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Anesthesia, Anesthesia Spinal
- Trial name
- NCT07851870
- Testing
- Intrathecal bupivacaine, morphine and atropine, General anaesthesia, Multimodal analgesia and antiemetic prophylaxis
- Where
- Indonesia
- Volunteers
- 63 people
- Sponsor
- Universitas Indonesia
Nausea, Postoperative, Vomiting, Postoperative
Carbohydrate Fluids and Post Operative Nausea and Vomiting
This study is a prospective randomized clinical controlled trial testing the effects of pre-operative >50 g pre-operative carbohydrate fluids (apple juice) on a patient's post-operative nausea and vomiting (PONV) incidence and…
- Trial name
- PONV (NCT06481670)
- Testing
- Carbohydrate drink
- Sponsor
- Boston Medical Center
Breast Cancer
GDF-15 and Its Relationship With Treatment-related ADverse Events in Breast Cancer
GRADE is trying to find out if there is a link between a hormone called GDF-15 and the side effects that people can experience when taking T-DXd. GDF-15 can be measured in the blood.
- Trial name
- GRADE (NCT07465172)
- Testing
- Blood collection for GDF-15
- Where
- 4 sites in United States, Australia and 1 more
- Volunteers
- 150 people
- Sponsor
- Breast Cancer Trials, Australia and New Zealand
Breast Neoplasms
Chinese Herbal Acupoint Application Combined With Triple Antiemetic Therapy for Prevention of Chemotherapy-Induced Nausea and Vomiting in Breast Cancer
The goal of this clinical trial is to learn whether Chinese herbal acupoint application, when added to standard three-drug anti-nausea treatment, can prevent nausea and vomiting caused by chemotherapy in people with breast…
- Trial name
- NCT07848984
- Testing
- Chinese Herbal Acupoint Application, Standard Triple Antiemetic Therapy
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Nausea and Vomiting Chemotherapy-Induced, Nausea Post Chemotherapy
Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC)
Chemotherapy often causes nausea and vomiting (CINV), and this is a major problem for the children being treated for cancer. To prevent this, a combination of two substances in fixed proportion (IV NEPA) was developed.
- Trial name
- NCT06904235
- Testing
- IV NEPA (fosnetupitant/palonosetron), Reference Treatment: IV ondansetron infusion, Reference Treatment: IV fosaprepitant infusion
- Where
- 20 sites in Greece, Poland and 2 more
- Volunteers
- 95 people
- Sponsor
- Helsinn Healthcare SA
Postoperative Nausea and Vomiting
Effects of taVNS Combined With Dexmedetomidine on POVN
To explore the effects and possible mechanisms of dexmedetomidine combined with taVNS on the incidence of postoperative nausea and vomiting in female patients undergoing laparoscopic surgery
- Trial name
- NCT07271147
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulator, Dexmedetomidine
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Affiliated Hospital of Nantong University
Vomiting in Infants and/or Children, Nausea
RCT of Olanzapine for Control of CIV in Children Receiving Highly Emetogenic Chemotherapy
Chemotherapy-induced nausea and vomiting (CINV) are among the most bothersome symptoms during cancer treatment according to children and their parents.
- Conditions
- Vomiting in Infants and/or Children, Nausea, Hematopoietic System--Cancer, Oncology
- Trial name
- NCT03118986
- Testing
- Olanzapine
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 161 people
- Sponsor
- The Hospital for Sick Children
Arthritis Knee, Postoperative Nausea
Oral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee Arthroplasty
This study aims to determine if oral dexamethasone provides clinically significant improvement in postoperative outcomes, specifically nausea and pain scores.
- Conditions
- Arthritis Knee, Postoperative Nausea, Postoperative Pain
- Trial name
- NCT04432259
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Henry Ford Health System
Digestive System Disorder, Dyspepsia
Domperidone in Treating Patients With Gastrointestinal Disorders
This phase III trial studies how well domperidone works in treating patients with gastrointestinal disorders. Domperidone may help control chronic gastrointestinal disorders and their symptoms, such as pain, bloating, and nausea…
- Conditions
- Digestive System Disorder, Dyspepsia, Esophagitis, Gastroesophageal Reflux Disease
- Trial name
- NCT01696734
- Testing
- Domperidone, Questionnaire Administration
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- M.D. Anderson Cancer Center
Idiopathic Gastroparesis, Diabetic Gastroparesis
Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis
To investigate the safety and efficacy of tradipitant versus placebo in relieving nausea and other symptoms of gastroparesis.
- Conditions
- Idiopathic Gastroparesis, Diabetic Gastroparesis, Gastroparesis
- Trial name
- NCT04028492
- Testing
- Tradipitant, Open Label Tradipitant
- Where
- 36 sites in United States
- Volunteers
- 979 people
- Sponsor
- Vanda Pharmaceuticals
Vomiting, Nausea
Inhaled Isopropyl Alcohol for Treatment of Nausea
To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.
- Conditions
- Vomiting, Nausea, Children, Only
- Trial name
- NCT05418244
- Testing
- Inhaled Isopropyl Alcohol, Oral Ondansetron
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo