Clinical trials: Near-Infrared Spectroscopy
Stroke, Cognitive Impairment
Effects of Hyperbaric Oxygen Combined With Aerobic Exercise on Working Memory Among Stroke Patients
This single-center randomized controlled trial enrolled stroke patients with working memory impairment. Participants were randomly divided into the hyperbaric oxygen combined low-intensity focused ultrasound intervention group…
- Trial name
- NCT07772947
- Testing
- Conventional rehabilitation therapy, Moderate-intensity aerobic exercise, Hyperbaric Oxygen Therapy (HBOT)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University
Healthy, Health Behavior
The Validation Study of Bioelectronics
The purpose of this study is to investigate the safe wearability and basic functions of the multi-modality sensors fabricated in the PI lab.
- Trial name
- NCT05397951
- Testing
- Multi-modality Noninvasive Biosensor, Oximeter, Portable Blood Pressure Monitor
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Posterior Cortical Atrophy
Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy
This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (PCA).
- Trial name
- PCA (NCT07191327)
- Testing
- HD-tDCS sessions, HD-tDCS sessions - Open-label (after randomized treatment)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Traumatic Brain Injuries, Brain Injuries,Traumatic
Doppler Ultrasonography Parameters and Mortality in Traumatic Brain Injury
The purpose of this study is to find out whether blood flow measurements of the brain and neck arteries, obtained with bedside Doppler ultrasonography are associated with neurological outcome and survival in adult patients with…
- Trial name
- NCT07890259
- Testing
- Transcranial and Carotid Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Obesity, Craving
Neurofeedback Based on Near-infrared Spectroscopy as a Therapy for Food Addiction in Obese Subjects.
The hypothesis is that the increase in dlPFC brain activity via near-infrared spectroscopy-based Neurofeedback (fNIRS-based NF) training based on near-infrared spectroscopy would allow an improvement of the eating behavior, thus…
- Trial name
- CaDOb (NCT05277714)
- Testing
- NF
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Low Bone Mineral Density, Muscle Oxygenation
Bone and Muscle Oxygenation in Military Test Pilots
This prospective, single-group interventional pilot study will evaluate the effects of a 12-week resistance and core stabilization exercise program on bone mineral density and resting muscle oxygenation in male military test…
- Trial name
- BMO-MTP (NCT07787143)
- Testing
- Supervised Resistance and Core Stabilization Exercise Program
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emine Merve Ersever
Emotional Distress
The Role of Cognitive Flexibility in Mindfulness Intervention: a Functional Near-infrared Spectroscopy Study
This study hopes to: explore the relationship between mindfulness mediation experiences and emotional distress and cognitive flexibility levels.
- Trial name
- NCT06103149
- Testing
- Mindfulness Intervention for Emotional Distress(MIED)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xinghua Liu
Anoxia
Cerebral Near-infrared Spectroscopy (NIRS) Monitoring Throughout Caesarean Deliveries
In this study the investigator would like to examine hemodynamic cerebral blood flow and brain function by the use of Invos cerebral oximetry in women undergoing cesarean section delivery.
- Trial name
- NCT02473978
- Testing
- INVOS Cerebral Oximetry
- Where
- Israel
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery
Near Infrared Spectroscopy for the Detection of Acute Kidney Injury in Children Following Cardiac Surgery
One in a hundred children is born with a heart defect. Some children require heart surgery within the first few days of life, while others can wait until they are older.
- Conditions
- Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery, Children
- Trial name
- NCT01382758
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Concussion, Brain, Concussion, Mild
The Role of Cerebral Oximetry in Pediatric Concussion Assessment
The purpose of this study is to determine whether there is a difference in cerebral oxygenation as measured by near-infrared spectroscopy (NIRS) in children with concussion and healthy controls.
- Conditions
- Concussion, Brain, Concussion, Mild, Traumatic Brain Injury
- Trial name
- NCT02036333
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Coronary Artery Disease
Intracoronary Imaging With NIRS-IVUS to Characterize Arterial Plaques
To characterize atherosclerotic coronary artery plaques using advanced intra-coronary imaging with a combined near-infrared spectroscopy and intravascular ultrasound catheter before and after percutaneous intervention
- Trial name
- NIRS-IVUS (NCT01694368)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Corewell Health West
Prematurity, Infections, NIRS
The Peripheral(-Muscle) Oxygenation and Perfusion Score as a New Non-invasive Tool to Predict Elevations in C-reactive Protein Levels in Neonates
This is a prospective, single-center Phase II observational study investigating the predictive value of the "Peripheral(-muscle) Oxygenation and Perfusion Score" (POP-Score), a novel non-invasive composite index, for early…
- Conditions
- Prematurity, Infections, NIRS, Near Infrared Spectroscopy, Preterm Neonates
- Trial name
- POP-Score (NCT07109856)
- Testing
- POP-Score Assessment, Near-Infrared Spectroscopy (NIRS)
- Where
- Austria
- Volunteers
- 93 people
- Sponsor
- Medical University of Graz
Congenital Disorders
Comparison of NIRS and Serum Lactate to Predict Poor Post-operative Outcomes
Mortality after neonatal cardiac repair remains significant, and neonates who have undergone operative repair of congenital heart disease may experience sudden and unexpected demise.
- Trial name
- NCT00485524
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Children's Healthcare of Atlanta
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Autism, Cerebral Palsy
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG).
- Trial name
- NCT03434080
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Regional Cerebral Oxygen Saturation
Regional Cerebral Oxygen Saturation Under General Anesthesia A Pilot Study
A total of 60 patients will be enrolled in the study: 20 each who receive surgery in beach chair position or Trendelenburg's position and 20 patients undergoing cardiac surgery.
- Trial name
- NCT02101242
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Charite University, Berlin, Germany
Congenital Heart Disease
Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery
The use of near infrared spectroscopy (NIRS) is a technique that has recently been incorporated by several other surgical specialties to measure tissue perfusion, such as in plastic surgery to allow for earlier detection of free…
- Trial name
- NCT07361523
- Testing
- Tissue oximeter (IntraOx)
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Coronary Atherosclerosis
ORACLE-NIRS: Lipid cORe Plaque Association With CLinical Events: a Near-InfraRed Spectroscopy Study
This is a multi-center, investigator initiated study that will prospectively examine treatment strategies and outcomes of patients who underwent clinically-indicated Near Infrared Spectroscopy (NIRS).
- Trial name
- ORACLE-NIRS (NCT02265146)
- Where
- 5 sites in United States
- Sponsor
- University of Texas Southwestern Medical Center
Hearing Loss
fNIRs, Listening Effort, and Speech Intelligibility
The purpose of the current study is to measure oxygenation in the PFC using fNIRS in a sample of older adults with hearing loss.
- Trial name
- NCT05330585
- Testing
- Hearing aids, Unaided
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sonova AG
Aortic Arch Surgery
Near Infrared Spectroscopy (NIRS)
This study is designed to assess the feasibility of evaluating cerebral saturation during critical periods of deep hypothermia circulatory arrest and Selective Antegrade Cerebral Perfusion.
- Trial name
- NCT01429324
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nonin Medical, Inc