Clinical trials: Near-Infrared Spectroscopy
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery
This study is a single-center, observational study designed to collect tissue spectrometric data related to tissue oxygenation.
- Conditions
- Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Ischemia Vascular, Tissue Ischemia
- Trial name
- NCT07786623
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Cerebral Desaturation, Cerebral Ischemia
Assessment of Cerebral Blood Flow Asymmetry in Cardiac Surgery Patients Undergoing Hypothermic Circulatory Arrest
Cerebral oxygen desaturation during cardiac surgery measured using near infrared spectroscopy (NIRS) derived cerebral oximetry has been associated with significant postoperative morbidity.
- Trial name
- COASTLINE (NCT03215589)
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Symptoms of Anxiety
Transcranial Photobiomodulation in Anxiety Disorders
The investigators have previously shown that safe, non-invasive methods of brain stimulation such as the administration of transcranial infrared light can result in improvements to cognition and emotion.
- Trial name
- NCT07133893
- Testing
- Attention bias assessment and modification, Transcranial photobiomodulation
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Francisco Gonzalez-Lima, PhD
Arteriosclerosis, Near-infrared Spectroscopy
Randomized-controlled Trial of a Combined vs. Conventional Percutaneous Intervention for Near-Infrared Spectroscopy Defined High-Risk Native Coronary Artery Lesions
Design: Single center, single-blind randomized controlled trial of patients with high risk native coronary artery lesions (defined as ≥2 contiguous yellow blocks on the block chemogram) requiring clinically indicated percutaneous…
- Conditions
- Arteriosclerosis, Near-infrared Spectroscopy, Peri-procedural Myocardial Infarction, Coronary Artery Disease
- Trial name
- CONCERTO (NCT02601664)
- Testing
- Combined Intervention, Conventional PCI
- Volunteers
- 3 people
- Sponsor
- North Texas Veterans Healthcare System
Burns, Pain
Effects of Virtual Reality Application on Pain Reduction and Cerebral Blood Flow in Robot Training in Burn Patients
The purpose of this study is to determine whether the application of virtual reality (VR) is effective in reducing training pain in robot-assisted gait training (RAGT) in patients with lower extremity burn.
- Conditions
- Burns, Pain, Virtual Reality
- Trial name
- NCT05004766
- Testing
- Robot assisted gait training with virtual reality
- Volunteers
- 10 people
- Sponsor
- Hangang Sacred Heart Hospital
Carotid Stenosis, Carotid Artery Diseases
Cerebral Oximetry During Awake Carotid Endarterectomy
Surgery to remove plaque from the carotid artery in the neck requires the artery to be clamped for a period of time. In some patients this reduces blood flow to the brain enough to cause temporary symptoms, and a temporary…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Brain Ischemia, Carotid Endarterectomy
- Trial name
- COACE (NCT07816081)
- Testing
- Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- Nguyen Toan Thang
Attention Deficit/Hyperactivity Disorder
Near Infrared Spectroscopy Neurofeedback Training for ADHD
Background Attention Deficit Hyperactivity Disorder (ADHD) is one of the most frequently diagnosed behavioural disorders in childhood that requires treatment(3-5% of children).
- Trial name
- ADHDNTx (NCT02205268)
- Testing
- Near infrared spectroscopy neurofeedback training
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- North Essex Partnership NHS Foundation Trust
Impaired Oxygen Delivery, Transplant; Failure, Liver
Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Patients Undergoing Liver Transplantation Surgery
Mixed venous oxygen saturation (SvO2) is an important parameter in the management of patient during liver transplantation surgery especially during portal vein clamping.
- Trial name
- NCT04778150
- Testing
- VO 100 medical device from Mespere LifeSciences
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Hospital, Geneva
Cervical Disc Disease, Cervical Stenosis
Is There a Risk of Perioperative Stroke Due to the Retraction Used During Anterior Cervical Discectomy?
In anterior cervical disc surgery, head and neck extansion position and, surgical retraction used while reaching the anterior surface of the cervical vertebra can be affect the carotid blood flow and constituting a risk for…
- Conditions
- Cervical Disc Disease, Cervical Stenosis, Cervical Disc Herniation
- Trial name
- NCT05717010
- Testing
- Near infrared spectroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Samsun University
Autism Spectrum Disorder
Improving ToM in Children With ASD Through VPT Training: Behavioral and fNIRS Study
This study aims to employ a longitudinal tracking research to investigate the effects of a visual perspective taking intervention on the development of theory of mind in children with autism.
- Trial name
- NCT06196060
- Testing
- Visual perspective taking training, Block building training, Thought-bubble training
- Where
- 3 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing Normal University
Hypoxic-Ischemic Encephalopathy Mild
Predictive Value of aEEG and Cerebral Oxygenation on Neurological Outcomes in Newborns With Mild Hypoxic-Ischemic Encephalopathy
Newborns with mild hypoxic-ischemic encephalopathy usually do not receive cooling treatment. However, some of these newborns may develop neurological problems later in life.
- Trial name
- NCT07393620
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uludag University
Nervous System Diseases, Healthy Subjects
Functional Near-infrared Spectroscopy in Unconscious Patients
The study design is a single-center prospective pilot study. Hypothesis: Results of cerebral fNIRS examination in unconscious patients with severe hemorrhagic or ischemic stroke in the ICU are congruent with the results of SSEP…
- Trial name
- fNIRS (NCT04746820)
- Testing
- single-center prospective pilot study
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Emanuela Keller
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage
This is a two-component prospective study of adult aneurysmal subarachnoid hemorrhage (aSAH) patients admitted to the Neurosciences Intensive Care Unit (NSICU) at UT Southwestern Medical Center.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm, Autonomic Nervous System Diseases
- Trial name
- NCT07577739
- Testing
- Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Near-Infrared Spectroscopy, Umbilical Cord Issue
"Improves Physiological Based Cord Clamping (PBCC) the Systemic and Cerebral Oxygenation in Term Infants?"
The first major intervention a newborn infant is facing following birth is clamping of the umbilical cord. This means separation of the infant from the placenta, the newborn becomes an independent individual, especially from a…
- Trial name
- NCT02763436
- Testing
- physiological-based cord clamping
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Medical University of Graz
Aortic Coarctation, Cardiac Output, Low
Correlation of Cardiac Index Measured by the PRAM Method With NIRS and Lactate Levels in Pediatric Aortic Coarctation Surgery
This prospective observational study aims to evaluate the correlation between cardiac index measured by the MostCare™ system (Pressure Recording Analytical Method, PRAM) and cerebral/renal regional oxygen saturation measured by…
- Trial name
- MostCare-Ped (NCT07568431)
- Testing
- MostCare (PRAM), Near-Infrared Spectroscopy (NIRS), Arterial Blood Gas with Lactate
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Konya City Hospital
Angina Pectoris, Angina, Unstable
SPECTACL: SPECTroscopic Assessment of Coronary Lipid
The purpose of this study is to evaluate a near-infrared (NIR) spectroscopy system that has been designed to identify the chemical composition of coronary artery plaques in patients undergoing a percutaneous coronary intervention…
- Conditions
- Angina Pectoris, Angina, Unstable, Myocardial Infarction
- Trial name
- SPECTACL (NCT00330928)
- Testing
- Near Infrared Spectroscopy (NIRS) Imaging, intravascular ultrasound (IVUS)
- Where
- 6 sites in United States, Canada
- Volunteers
- 106 people
- Sponsor
- Infraredx
Cerebral Oxygenation, Peripheral Oxygenation
Manual Versus Autoflow Ventilation During Anesthesia Inductıon in Geriatric Patients
The objective of this study is to compare the effects of manual ventilation and AutoFlow ventilation, administered during the induction of general anesthesia, on cerebral (s-rSO₂) and peripheral (somatic) oxygenation (p-rSO₂) in…
- Conditions
- Cerebral Oxygenation, Peripheral Oxygenation, Geriatrics, Ventilation
- Trial name
- NCT07582913
- Testing
- Manual Mask Ventilation, AutoFlow Mechanical Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia
Muscle and Cerebral Oxygenation Under EVAR of AAA: GA vs LA
The purpose of this study is to determine the effect of General versus Local Anaesthesia on muscle and cerebral oxygenation under EVAR-treatment in a prospective unblinded randomised controlled trail.
- Trial name
- NCT02555046
- Testing
- Local Anesthesia
- Volunteers
- 26 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obstructive Sleep Apnea Syndrome
Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers
The goal of this trial is to assess the performance of the OxiplexTS-an absolute near-infrared oximeter-as an instrument to measure brain oxygenation and hemodynamics in sleep medicine as well as in the broader field of…
- Trial name
- NIRS-OSAS (NCT00591591)
- Testing
- OxiplexTS
- Where
- 4 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- ISS, Inc.
Conventional Cardiac Surgery With Bypass
Peripheral Four-wavelength Near-infrared Spectroscopy Measurement: a Comparison Between EQUANOX and O3 in Cardiac Surgery
Near-infrared spectroscopy (NIRS) is a continuous and non-invasive technology that measures regional tissue oxygen saturation (rSO2).
- Trial name
- NIRS-8 (NCT02847273)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon