Clinical trials: Near-Infrared Spectroscopy
Depression
Accelerated iTBS for Depression: Monitoring Brain Hemodynamics With Simultaneous iTBS/fNIRS
This study will investigate the cortical hemodynamic response variability of an accelerated form of TBS stimulation over left dorsolateral prefrontal cortex (DLPFC) using a concurrent TBS/fNIRS setup.
- Trial name
- NCT06971549
- Testing
- Accelerated iTBS
- Where
- Hong Kong
- Volunteers
- 1 people
- Sponsor
- The Hong Kong Polytechnic University
ADHD - Attention Deficit Disorder With Hyperactivity
Brain Stimulation and Attention Control in Children With ADHD
The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control.
- Trial name
- NCT07182344
- Testing
- Intermittent Theta Burst Stimulation to Right DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Respiratory Muscle Blood Flow
Clinical Respiratory Evaluation Using Spectroscopy Trial
Respiratory muscles (the muscles used to breathe) need more blood (and oxygen) when their workload increases. It is difficult to measure respiratory muscle blood flow (RMBF) without invasive techniques.
- Trial name
- CREST (NCT01321411)
- Testing
- Near Infrared Spectroscopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Alzheimer´s Disease
Vagus Somatosensory Evoked Potentials and Near-infrared Spectroscopy in the Early Diagnosis of Dementia
In its long preclinical course, AD shows a spreading pattern of specific pathology in a uniform sequence of predictable steps including brainstem nuclei in early stages.
- Trial name
- Vogel (NCT02224326)
- Where
- Germany
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Sepsis, Inflammation
Tissue Near InfraRed Spectroscopy (NIRS) in Critically Ill Patients
Hypotheses: 1. In the acute phase of early illness, tissue oxygen saturation and vascular occlusion test (VOT) are important adjuncts in differentiating severe critical illness requiring ICU admission from patients benefiting…
- Conditions
- Sepsis, Inflammation, Shock
- Trial name
- NCT01528358
- Where
- Canada
- Volunteers
- 672 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cognitive Dysfunction, Postoperative, Cognitive Dysfunction
Assessment of Brain Oxygen Drops During Surgery and Related Risk Factors for Cognitive Problems After Heart Surgery
This study examines whether decreases in brain oxygen levels during cardiac surgery are linked to postoperative cognitive dysfunction and identifies other factors that may increase the risk of cognitive impairment.
- Conditions
- Cognitive Dysfunction, Postoperative, Cognitive Dysfunction, Cardiac Surgery
- Trial name
- NCT07361068
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Arterio-venous Fistula
NIRS Measurement After SCP Block
Peripheral regional anesthesia induces a sympathectomy-like effect with neurovascular changes causing increased arterial blood flow and venodilatation .
- Trial name
- NCT03044496
- Testing
- Supraclavicular nerve block
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Marienhospital Stuttgart
Pain
Functional Near Infrared Spectroscopy to Detect Pain in Young Children Under General Anesthesia
This is a three-phase pilot prospective study to develop a devise capable of detecting changes in cortical blood volume and oxygenation due to noxious stimuli.
- Trial name
- NCT04362423
- Testing
- fNIRS
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy, Gait Disorders, Neurologic
Exoskeleton and Brain Activity With fNIRS
Background. Force control is one of the major parameter of motor activity. There is few study concerning the cortical activity imply for different levels of force during gait. Objective.
- Trial name
- ExoNIRS (NCT05298943)
- Testing
- walking in 4 situations
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Tissue Injury, Surgery
Is Regional Oxygen Saturation Effective in Predicting Perfusion Parameters and Patient Outcomes in Liver Resection
Sudden hypotension, which may develop during liver resection operations performed under general anesthesia, can affect the patient satisfaction at a high rate by causing complications during and after the operation as a result of…
- Conditions
- Tissue Injury, Surgery, Absorption; Disorder
- Trial name
- NCT05077397
- Testing
- StO2, O3
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Microvascular Reactivity, Tissue Oxygen Saturation
The Effect of Hydroxyethylstarch 6% 130/0.4 in a Balanced Electrolyte Solution (Volulyte®) Compared to Gelatine (Geloplasma®) on Microvascular Reactivity and Tissue Oxygen Saturation During Haemodilution Measured With Near-infrared Spectroscopy
The aim of this study is to compare 6% hydroxyethyl starch (HES) 130/0.4 in a balanced electrolyte solution (Volulyte®) with modified fluid gelatin (Geloplasma®) as the priming solution for the cardiopulmonary bypass (CPB)…
- Trial name
- NCT02034682
- Testing
- Volulyte 6%, Geloplasma
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Cardiac Arrest (CA)
Integrated Near-Infrared Spectroscopy and Hemodynamic Monitoring for Cerebral Autoregulation in Post-Cardiac Arrest Care Neuroprognostication
Neurological outcome is the primary outcome for post-cardiac arrest patients. Hypoxic-ischemic brain injury is a key element in post-cardiac arrest syndrome, and remains the leading cause of mortality and morbidity in…
- Trial name
- NCT07875348
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Diabetes, Peripheral Arterial Occlusive Disease
Evaluate the Correlation of NIRS, ABI, Exercise, baPWV and Albuminuria With Peripheral Artery Occlusion Disease (PAD) and Other Atherosclerosis Outcomes
By utilizing Near infrared spectroscopy (NIRS), the local blood flow, tissue oxygenation (StO2), and recovery time of ischemic leg; can be determined.
- Trial name
- NCT03378024
- Testing
- oscillometric (Omron Colin co)
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cardiogenic Shock, Cardiac Arrest
Lower Limb Surveillance During VA-ECLS
Temporary cardiac support by VA-ECLS can lead to lower limb ischemia. The aim of this study is to evaluate a multi-modal strategy (physical examination, NIRS monitoring and angiography through the reperfusion canula) of lower…
- Conditions
- Cardiogenic Shock, Cardiac Arrest, Lower Limb Ischemia
- Trial name
- NCT03910062
- Testing
- Lower limb angiography via the reperfusion cannula and NIRS monitoring
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Cerebral Palsy (CP), Intraventricular Hemorrhage Neonatal
Intelligent Physiological Monitoring to Predict Preterm Brain Injury
Cerebral palsy (CP) remains prevalent among very (28-31 weeks) and extremely (<28 weeks) preterm infants. Prematurity-related brain injuries (high-grade intraventricular haemorrhage, IVH or periventricular leukomalacia, PVL)…
- Conditions
- Cerebral Palsy (CP), Intraventricular Hemorrhage Neonatal, Periventricular Leukomalacia, Neurodevelopmental Delay
- Trial name
- AI4NICU (NCT07880431)
- Testing
- EEG, NIRS
- Where
- Ireland
- Volunteers
- 413 people
- Sponsor
- University College Cork
Acute Respiratory Failure
Brain-lung Interaction During Acute Respiratory Failure
Acute hypoxemic de novo respiratory failure (AHRF) is a common cause of admission to the intensive care unit (ICU). Its main cause is community-acquired pneumonia.
- Trial name
- BrainFlow (NCT07279831)
- Testing
- EEG/NIRS/EMG
- Where
- 2 sites in France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Physiological Responses to High-Intensity Exercise
Effects of the Q-Collar During High-Intensity Cycling Exercise
This study examined the effects of wearing the Q-Collar during high-intensity cycling exercise. Eleven recreationally trained male participants completed two 5-kilometer cycling time trials: one while wearing the Q-Collar and one…
- Trial name
- NCT07808710
- Testing
- Q-Collar™
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Hearing Loss
Use of Functional Near-infrared Spectroscopy to Investigate Role of Human Auditory Cortex Plasticity and Multi-sensory Integration on Cochlear Implant Performance After Single-sided Deafness
The timing of brain changes that may influence hearing rehabilitation within human A1 after single-sided deafness (SSD) is not known. The goal is to determine when A1 neural plasticity occurs following SSD onset.
- Trial name
- NCT03713554
- Testing
- FNIRS Observational
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Placental Insufficiency, NEC - Necrotizing Enterocolitis
Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.
Antenatal absent or reversed end-diastolic flow (AREDF) velocity through the umbilical arteries places preterm infants at significant risk for developing gastrointestinal complications, such as feeding intolerance, necrotizing…
- Conditions
- Placental Insufficiency, NEC - Necrotizing Enterocolitis, Newborn, Premature, Feeding Disorder Neonatal
- Trial name
- AREDF-SO (NCT02971566)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Parkinson's Disease
Non-invasive Measurement of Brain Oxygen Levels in People With Subthalamic Deep Brain Stimulators
The purpose of this study is to determine if deep brain stimulation can change brain oxygen levels in people with Parkinson's Disease.
- Trial name
- NCT02278406
- Testing
- Deep brain stimulator
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Beth Israel Deaconess Medical Center