Clinical trials: Near-infrared Spectroscopy
Depressive Disorder
Research on the Biological Mechanism of the Efficacy of Psychotherapy for Depression Based on the fNIRS
In this project, the investigators will implement medication therapy, psychotherapy, and a combination of medication therapy with psychotherapy, specifically utilizing IPT, in patients with depression.
- Trial name
- NCT05927129
- Testing
- Antidepressant, Psychotherapy IPT, The combination of antidepressant and IPT
- Where
- China
- Volunteers
- 90 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Anesthesia, Consciousness, Loss of
Detection and Classification of Levels of Consciousness Using Parietal EEG-fNIRS During Anesthesia
The current evaluations of the levels of consciousness during anesthesia have limited precision. This can produce negative clinical consequences such as intraoperative awareness or neurological damage due to under- or…
- Trial name
- NCT05112042
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Liver Cirrhosis, Early Allograft Dysfunction
Intraoperative Assessment of Microcirculatory Function Using Vascular Occlusion Test During Liver Transplantation
Early allograft dysfunction (EAD) remains one of the most important complications following orthotopic liver transplantation (OLT).
- Trial name
- NCT07658794
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Ippokrateio General Hospital of Thessaloniki
Hypoxia, Brain, Premature Birth
PREMOD2 With Near Infrared Spectroscopy Sub-study
Early hemodynamic effects (within 3 hours of life) of Delayed Cord Clamping compared to Umbilical Cord Milking are still unknown.
- Trial name
- PREMOD2 (NCT03145142)
- Testing
- Umbilical cord milking, Delayed Cord Clamping
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 121 people
- Sponsor
- Sharp HealthCare
Placental Insufficiency, NEC - Necrotizing Enterocolitis
Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.
Antenatal absent or reversed end-diastolic flow (AREDF) velocity through the umbilical arteries places preterm infants at significant risk for developing gastrointestinal complications, such as feeding intolerance, necrotizing…
- Conditions
- Placental Insufficiency, NEC - Necrotizing Enterocolitis, Newborn, Premature, Feeding Disorder Neonatal
- Trial name
- AREDF-SO (NCT02971566)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Out-of-hospital Cardiac Arrest (OHCA)
Cerebral Near Infrared Spectroscopy in Out-of-Hospital Cardiac Arrest and Neurological Prognosis
Out-of-hospital cardiac arrest (OHCA) prognosis remains poor : 7% of patients surviving without neurological impairment. 65% of patients dying after hospital admission were neurologically impaired.
- Trial name
- NISOHCA (NCT06972329)
- Testing
- Cerebral Near infrared spectroscopy (NIRSc).
- Where
- 6 sites in France
- Volunteers
- 542 people
- Sponsor
- Central Hospital, Nancy, France
Cerebral Oxygen Desaturation, Post-operative Delirium
Cerebral Oxygenation in Total Hip Arthroplasty Patients
We plan to investigate the relationship between hypotensive epidural anesthesia for hip arthroplasty and cerebral oxygen saturation.
- Trial name
- THANIRS (NCT02325154)
- Testing
- Cerebral Oximeter
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Intraventricular Hemorrhage of Prematurity, Complications of Prematurity
Cerebral Oxygenation and Autoregulation in Preterm Infants
Premature infants are at high risk for variations in blood pressure and oxygenation during the first few days of life. The immaturity of the premature brain may further predispose these infants to death or the development of…
- Trial name
- Early NIRS (NCT02147769)
- Testing
- NIRS monitoring
- Where
- 7 sites in United States
- Volunteers
- 111 people
- Sponsor
- Stanford University
Urea Cycle Disorder
Functional Evaluation in Patients With Urea Cycle Disorders (UCD) During a Driving Task
This study is being done to understand how the brain works while people with urea cycle disorder (UCD) perform driving tasks that range from easy to difficult and to look at how that compares to traditional tests of thinking and…
- Trial name
- NCT07701694
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Mitral Regurgitation
The Effect of Percutaneous Superior Venae Cava Cannulation Clamping on Cerebral Near Infrared Spectroscopy in MICS
The use of minimally invasive cardiac surgery has progressed over the last 5-10 years to allow access to the heart through a small incision in the right chest.
- Trial name
- NIRSinMICS (NCT01166841)
- Testing
- PSVC line clamped
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Healthy
Accuracy of the O2 MedTech PMS-3000 Monitor
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- NCT01418079
- Testing
- O2 MedTech cerebral oximeter (Oxygen desaturation)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- O2 MedTech, Inc.