Clinical trials: Neck Dissection
SHOULDER DYSFUNCTION
Virtual Reality For Shoulder Dysfunction Post Neck Dissection Surgeries
The goal of this clinical trial study: is to determine the effect of Virtual reality on pain and function for shoulder dysfunction post neck dissection surgeries.
- Trial name
- NCT06257238
- Testing
- Fully immersive Head-Mounted Display Virtual Reality, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Cancer
The Efficacy of Lymph Node Dissection for Stage IIICr of Cervical Cancer(CQGOG0103)
This is an national, prospective, multicenter and randomized clinical study designed to determine if patients with stage IIICr of cervical cancer have longer PFS and/or OS with lymph node dissection before CCRT when compared to…
- Trial name
- NCT04555226
- Testing
- Lymph node dissection, Standard chemoradiation±pembrolizumab, Chemoradiation± pembrolizumab
- Where
- China
- Volunteers
- 452 people
- Sponsor
- Chongqing University Cancer Hospital
Locally Advanced Head and Neck Squamous Cell Carcinoma
CLEAR (Cervical Lymphatic Exclusion in Adjuvant Radiation)
The goal of this clinical trial is to learn if selectively omitting postoperative cervical irradiation is a safe and feasible treatment strategy for patients with resected, locally advanced squamous cell carcinoma of the head and…
- Trial name
- CLEAR (NCT07755449)
- Testing
- IMRT OR VMAT Radiotherapy excluding cervical radiation
- Where
- Spain
- Volunteers
- 101 people
- Sponsor
- Institut Català d'Oncologia
Thyroid Cancer, Thyroidectomy With Central Lymph Node Dissection
Does Parathyroid Autofluorescence Reduces Unintensional Parathyroidectomy During Total Thyroidectomy With Central Lymph Node Compartment Dissection
The aim of the study is to evaluate the effectiveness of autofluorescence in the intraoperative preservation of parathyroids during total thyroidectomy with central lymph node compartment dissection.
- Trial name
- FLUOBCC (NCT04339478)
- Where
- 2 sites in Greece, Jordan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Uterine Cervical Neoplasms
LESs Surgical Radicality for EaRly Stage Cervical Cancer
This study is an open-label, multicenter, randomized, phase II non-inferiority trial (proof of concept study). Its purpose is to evaluate the safety and efficacy of extrafascial hysterectomy plus pelvic-lymph node dissection…
- Trial name
- LESSER (NCT02613286)
- Testing
- Extrafascial Hysterectomy, Modified radical hysterectomy
- Volunteers
- 40 people
- Sponsor
- Hospital de Câncer de Pernambuco
Thyroid Cancer
Lateral Cervical Node Dissection in Differentiated Thyroid Cancer.
The objective of this study is to compare shoulder and neck morbidity and the effectiveness of cervical lateral nodal dissection in patients with differentiated thyroid cancer and lateral metastases between the anterior and…
- Trial name
- NCT06149637
- Testing
- Traditional neck dissection approach, Anterior neck dissection approach
- Where
- Colombia
- Volunteers
- 62 people
- Sponsor
- Centro de Excelencia en Enfermedades de Cabeza y Cuello
Cervical Artery Dissection, Carotid Artery Dissection
To Determine the Feasibility of a Clinical Trial Comparing Anticoagulants Versus Antiplatelets in the Acute Treatment of Patients With Cervical Artery Dissection
This is a feasibility study to determine if a sufficient number of patients can be recruited throughout the United Kingdom and whether sufficient endpoints can be generated for a full scale therapeutic trial of anticoagulants…
- Conditions
- Cervical Artery Dissection, Carotid Artery Dissection, Vertebral Artery Dissection, Stroke
- Trial name
- CADISS (NCT00238667)
- Testing
- Antiplatelet (Aspirin, Dipyridamole, clopidogrel), Anticoagulant (Unfractionated Heparin, LMW Heparin, Warfarin)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- St George's, University of London
Nasopharyngeal Cancinoma (NPC)
Multimodal Evaluation-Guided Surveillance-Intervention With Endoscopic Selective Neck Dissection for Post-Radiotherapy N3 Nasopharyngeal Carcinoma
This randomized trial evaluates a multimodal surveillance strategy in nasopharyngeal carcinoma patients with high-risk N3 cervical lymph node involvement after radiotherapy.
- Trial name
- NCT07692906
- Testing
- Multimodal Evaluation-Guided Surveillance Strategy
- Volunteers
- 80 people
- Sponsor
- Xuelei Ma MD
Thoracoabdominal Aneurysms
Visceral Manifold and Unitary Device Study for the Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of the Visceral Manifold and Unitary Device Study is to assess the use of the thoracic bifurcation and the visceral manifold or the unitary device to repair thoracoabdominal aortic aneurysms in patients…
- Trial name
- NCT02294435
- Testing
- Visceral Manifold and Thoracic Bifurcation, Unitary Manifold
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Sanford Health
Oral Cancer, Lymph Node Metastasis
Neck Observation or Elective Neck Dissection in cT1N0M0 OSCC
To evaluate the clinical outcomes of 2-year lymph node metastasis rate, disease-free survival, overall survival, and health-related quality of life in the patients with cT1N0M0 oral squamous cell carcinoma, who receive primary…
- Trial name
- NCT06623266
- Testing
- Neck management
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huashan Hospital
Saccular and Fusiform Aneurysms, Pseudoaneurysm
Targeting Real World Usage In Stroke Treatment
TRUST Registry is an observational, prospective, long-term, post-market surveillance registry of subjects treated with WallabyPhenox flow modulation devices, stent systems, bifurcation aneurysm implants including their HPC…
- Conditions
- Saccular and Fusiform Aneurysms, Pseudoaneurysm, Vascular Dissection, Perforation
- Trial name
- TRUST (NCT07474935)
- Testing
- Aneurysm Treatment with a Neurovascular Flow Diverter, Dissection Treatment with a Neurovascular Flow Diverter, Perforation Treatment with a Neurovascular Flow Diverter
- Where
- 13 sites in France, Germany and 3 more
- Volunteers
- 5,000 people
- Sponsor
- Phenox GmbH
Esophageal Cancer
Two-field Versus Three-field Lymphadenectomy in Thoracic Esophageal Carcinoma Without Cervical Lymph Node Involvement
The purpose of this study is to compare the lymph node dissection results and prognosis in thoracic esophageal carcinoma patients without cervical lymph node involvement by preoperative CT and/or ultrasound treated by two-field…
- Trial name
- NCT02448953
- Testing
- Two-field lymphadenectomy, Three-field lymphadenectomy
- Where
- China
- Volunteers
- 786 people
- Sponsor
- Chinese Academy of Medical Sciences
Hemorrhage, Hypocalcemia
The No-Tie Technique Using the Harmonic Scalpel in Total Thyroidectomy With Central Neck Dissection: A Prospective Randomized Study
To investigate the safety and efficacy of the no-tie technique using the harmonic scalpel (HS) in terms of the operating time and complications in total thyroidectomy with central neck dissection (CND).
- Conditions
- Hemorrhage, Hypocalcemia, Vocal Cord Palsy
- Trial name
- NCT00506103
- Where
- South Korea
- Sponsor
- Soonchunhyang University Hospital
Laryngeal Neoplasms, Malignant Neoplasm of Supraglottis Primary
A Multicenter, Randomized, Case-control Study of Unilateral vs Bilateral Neck Dissection for cN0 Supraglottic Laryngeal Cancer
Supraglottic laryngeal carcinoma patients with clinically negative neck (cN0) will be randomized divided into two groups. Patients in case group will undergo unilateral neck dissection (II-IV) while bilateral neck dissection…
- Conditions
- Laryngeal Neoplasms, Malignant Neoplasm of Supraglottis Primary, Neck Dislocation
- Trial name
- NCT03392220
- Testing
- Unilateral Neck Dissection, Bilateral Neck Dissection
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Thyroidectomy, Thyroid Cancer
Evaluation of Central Compartment Dissection Without Thyroidectomy
In accordance with the current guidelines,papillary thyroid microcarcinoma such as turmo invasive nerve or trachea, requires total thyroidectomy for follow-up iodine-131 treatment.In the course of clinical work, if the patient…
- Conditions
- Thyroidectomy, Thyroid Cancer, Central Compartment Neck Dissction
- Trial name
- NCT03454464
- Testing
- Conventional, central neck dissection first
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Esophageal Carcinoma in Situ AJCC V7
A Comparative Study of Endoscopic Submucosal Dissection and Photodynamic Therapy for Early Esophageal Cancer
The purpose of this study was to compare the efficacy and safety of Photodynamic therapy (PDT) and Endoscopic submucosal (ESD) dissection in the treatment of early esophageal cancer.
- Trial name
- NCT05208775
- Testing
- PDT, ESD
- Volunteers
- 46 people
- Sponsor
- The First Affiliated Hospital of Henan University of Science and Technology
Oropharyngeal Squamous Cell Cancer
Phase II Treatment Stratification Trial Using Neck Dissection-Driven Selection to Improve Quality of Life for Low Risk Patients With HPV+ Oropharyngeal Squamous Cell Cancer
Investigators will determine whether a treatment paradigm of up-front neck dissection, to more accurately pathologically stage patients, minimizing the number of treatment modalities in patients with low risk oropharyngeal…
- Trial name
- NCT02784288
- Testing
- Neck Dissection, Standard-of-Care (SOC) Transoral Surgery of Primary Site, SOC Radiation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan Rogel Cancer Center
Thyroid Diseases, Thyroid Neoplasms
Thyroid Health Outcomes Registry for Surgery
THORS is a single-center ambidirectional observational cohort study conducted at Moscow Multidisciplinary Clinical Center "Kommunarka".
- Conditions
- Thyroid Diseases, Thyroid Neoplasms, Thyroid Cancer, Thyroid Nodules
- Trial name
- THORS (NCT07812779)
- Volunteers
- 3,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Esophageal Squamous Cell Carcinoma (ESCC)
Neoadjuvant Immunotherapy Combined With Chemotherapy Sequenced With Endoscopic Resection for Esophageal Cancer (Endosurgery-02)
This single-center, prospective, single-arm study will evaluate whether giving neoadjuvant chemoimmunotherapy can safely shrink esophageal cancer and allow organ-preserving endoscopic removal in selected patients.
- Trial name
- Endosurgery-02 (NCT07317609)
- Testing
- Tislelizumab, Carboplatin, Nab-paclitaxel
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Esophageal Cancer, Recurrent Laryngeal Nerve
The Value of Near-Infrared Fluorescence Imaging in the Protection of the Recurrent Laryngeal Nerve During Minimally Invasive Esophagectomy
The goal of this clinical trial is to learn whether the application of indocyanine green near-infrared imaging system can accurately locate the recurrent laryngeal nerve (RLN) during lymph node dissection in esophageal cancer…
- Conditions
- Esophageal Cancer, Recurrent Laryngeal Nerve, ICG (Indocyanine Green), Lymph Node Dissection
- Trial name
- NCT07406815
- Testing
- ICG (Indocyanine Green)
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Fujian Medical University Union Hospital