Clinical trials: Necrotic Pulp
Necrotic Pulp
Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth
Clinically compare the post-operative pain , incidences post-operative swelling , post-operative number of analgesic tablets taken by patient and amount of bacterial load reduction after using 50% Commiphora Myrrh Chemomechanical…
- Trial name
- NCT06310044
- Testing
- Root canal irrigant Commiphora Myrrh 50%
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp
Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical Periodontitis
Earlier, it was believed that successful regeneration cannot be achieved once tooth has become infected. However, recent studies suggest that regenerative endodontics may in fact be possible in teeth with pulpal necrosis and…
- Trial name
- NCT04606719
- Testing
- Advanced Platelet Rich fibrin
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp, Apical Periodontitis
Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical Periodontitis
The aim of this prospective, randomized, controlled double-blind study is to evaluate the effectiveness of biodentine compared with MTA used as pulp space barrier on discoloration of teeth after regenerative based non-obturation…
- Trial name
- NCT04018456
- Testing
- Biodentine, White MTA
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Necrotic Pulp, Post Operative Pain
Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp
The aim of this study is to assess the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction.
- Trial name
- NCT06116214
- Testing
- Vachellia Nelotica, sodium hypochlorite
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp, Chronic Apical Periodontitis
Mechanical Vs Chemomechanical Method For Calcium Hydroxide Removal
Type of study: Randomised Clinical trial To compare the effectiveness of Mechanical and Chemomechanical methods in the removal of Water-based Calcium hydroxide medicament from endodontic system.
- Trial name
- NCT05744661
- Testing
- Mechanical Method, Chemomechanical Method
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Necrotic Pulp
Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth
The maintenance of the deciduous tooth until its physiological exfoliation occurs is one of the main objectives of pediatric dentistry.
- Trial name
- NCT04587089
- Testing
- Irrigation, Filling with Guedes-Pinto Paste, Filling with CTZ Paste
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Necrotic Pulp
Effect of Apical Enlargement to Different Preparation Sizes and Tapers on Pain and Bacterial Reduction in Necrotic Pulp
The aim of this prospective randomized clinical trial is to evaluate the effect of different apical size and taper preparation (35. 04; 35. 06; 45. 04 and 45.
- Trial name
- NCT05620147
- Testing
- Root canal instrumentation EdgeFile X7 to size #35/0.06, Root canal instrumentation EdgeFile X7 to size #45/0.04, Root canal instrumentation EdgeFile X7 to size #45/0.06
- Volunteers
- 56 people
- Sponsor
- Cairo University
Necrotic Pulp, Apical Periodontitis
Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.
the aim of this study is to compare the effect of using Diclofenac Sodium Versus Calcium Hydroxide as Intracanal medication on intensity of postoperative pain, bacterial load reduction after root canal preparation and periapical…
- Trial name
- NCT05582421
- Testing
- Diclofenac Sodium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp
Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors
Regenerative endodontic procedures (REPs) are the most recent proposal to manage immature permanent teeth with necrotic pulps. So in this study, the investigator will evaluate the clinical and radiographical revitalization…
- Trial name
- NCT05522270
- Testing
- revitalization by concentrated growth factor
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ahmad Elheeny
Necrotic Pulp
Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using Moringa oleifera leaf extract solution during chemo-mechanical preparation, versus 2.5% NaOCl…
- Trial name
- NCT05348824
- Testing
- Moringa oleifera leaf, Sodium hypochlorite
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp, Single Root Teeth
Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling
aim of the study will be conducted to compare the effect of MTA fill apex sealer and endo sequence bioceramic sealer in obturation on the intenisty of postoperative pain and the incidence of post operative swelling in patient…
- Trial name
- NCT05419752
- Testing
- bioceramic sealer, MTA, resin sealer
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp With Symptomatic Apical Periodontitis
Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .
Calcium hydroxide is advocated as an intracanal medication for various purposes, including prevention of post-treatment symptoms.
- Trial name
- NCT05021809
- Testing
- Calcium hydroxide intracanal medication application
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Necrotic Pulp
Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants
To measure the Effect of Rosmarinus Officinalis versus 2.5%Sodium Hypochlorite as Root canal Irrigants on the Intensity of post-operative pain and Bacterial Reduction in asymptomatic necrotic Mandibular premolars.
- Trial name
- NCT05289843
- Testing
- Rosmarinus Officinallis
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Treatment, Periodontitis, Apical
Treatment of Young Permanent Teeth With Different Adjuvant Approaches
To determine microbiology assessment of infected root canal in young permanent teeth, as well as antimicrobial efficiency of different adjuvant treatment modalities including photodynamic therapy (PDT), high-power diode laser…
- Conditions
- Treatment, Periodontitis, Apical, Necrotic Pulp
- Trial name
- NCT05291195
- Testing
- Laser-device group, Essential Oil, Sodium hypochlorite group
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Necrotic Pulp
Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using 20mg/ml propolis nanoparticles extract solution during chemo-mechanical preparation, versus…
- Trial name
- NCT05146713
- Testing
- Propolis nanoparticles extract solution, sodium hypochlorite
- Volunteers
- 44 people
- Sponsor
- Cairo University
Post-Operative Pain, Chronic, Necrotic Pulp
Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
Propolis is a resinous product of honeybees. Propolis is said to be effective against resistant microorganisms inside the root canal compared to the gold standard medication known as calcium hydroxide.
- Trial name
- NCT04983524
- Testing
- propolis, Calcium Hydroxide
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp
Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite
This study aims to compare the effect of 2% curcumin solution versus 2.5% sodium hypochlorite as irrigating solutions in necrotic mandibular molars in terms of postoperative pain and antibacterial effect.
- Trial name
- NCT04728386
- Testing
- curcumin solution, sodium hypochlorite
- Volunteers
- 38 people
- Sponsor
- Cairo University
Necrotic Pulp, Periapical; Infection
Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.
- Trial name
- NCT04646538
- Testing
- Regenerative Endodontics Procedures (REPs)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Necrotic Pulp
Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria
The aim of this study is to compare the degree of postoperative pain and the antimicrobial effect in terms of bacterial count reduction after using co-amoxiclav-clindamycin solution versus MTAD and sodium hypochlorite irrigating…
- Trial name
- NCT04035070
- Testing
- co-amoxiclav-clindamycin solution, MTAD, 2.5% sodium hypochlorite
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Acute, Necrotic Pulp
The Frequency Of Sodium Hypochlorite Extrusion During Endodontic Treatments
Sodium hypochlorite is a commonly used irrigation agent. However, the solution may extrude beyond the apex of tooth and cause pain during the treatment.The aim of this prospective observational investigation is to determinate the…
- Trial name
- NCT04262362
- Testing
- Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bulent Ecevit University