Clinical trials: Needs Assessment
Heart Failure With Reduced Ejection Fraction (HFrEF)
Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)
The present study is a multicenter interventional non randomised study in patients requiring an implantable device for cardiac resynchronization therapy.
- Trial name
- ECHO-LBBp (NCT06689111)
- Testing
- Left bundle branch pacing lead, CRT with the standard method through cs
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University Hospital of Patras
High-need Older Adults
High-need Community Older Adults Care Delivery Model
This study is proposed to: (1) establish a "High-need Community Older Adults Care Delivery Model" (HCOACDM) as a guide to handle complex needs of the high-need community older adults by the care managers at community care…
- Trial name
- HCOACDM (NCT03864471)
- Testing
- HCOACDM, Routine care
- Where
- Taiwan
- Volunteers
- 165 people
- Sponsor
- Kaohsiung Medical University
Smoking Behavior, Special Needs Child
Evaluation of the Effects of Passive Smoking and Parental Stress on Challenging Behaviors in Mentally Retarded Children With Urine Cotinine Levels
This research was planned to determine the effect of environmental cigarette smoke exposure and parenting stress level on the severity of challenging behaviors in mentally disabled children
- Trial name
- smoking (NCT06691022)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Tokat Gaziosmanpasa University
Non-small Cell Lung Cancer, Stereotactic Body Radiotherapy
LIVELUNG - Impact of CGA in Patients Diagnosed With Localized NSCLC Treated With SBRT
Older patients with non-small cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT) often die from other causes than lung cancer due to age-related comorbidities.
- Conditions
- Non-small Cell Lung Cancer, Stereotactic Body Radiotherapy, Comprehensive Geriatric Assessment
- Trial name
- LIVELUNG (NCT05919641)
- Testing
- Comprehensive Geriatric Assessment
- Where
- 4 sites in Denmark
- Volunteers
- 130 people
- Sponsor
- Odense University Hospital
Hepatocellular Carcinoma
PAtient-PHYsician Relationship Assessment
I) Introduction Patients with cancer face difficult choices that require balancing competing priorities such as survival, functional capacity and symptom relief.
- Trial name
- PAPHYRA (NCT05729230)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Erasme University Hospital
Physical Inactivity, Overweight or Obesity
eMOTION: Examining Affective Mechanisms in Physical Activity Engagement
This early-phase trial will test intervention strategies to influence affective mechanisms underlying physical activity and determine whether changes in those mechanisms result in change in physical activity behavior among…
- Conditions
- Physical Inactivity, Overweight or Obesity, Cancer
- Trial name
- NCT06570642
- Testing
- Physical Activity Goals mHealth Intervention, TYPE/CONTEXT enhancement, SAVOR enhancement
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Temporomandibular Disorders (TMD)
Occlusal Adjustments Needed for Michigan Splints Made Using Different Digital Bite Records
This clinical study evaluated digital occlusal recording methods used in the fabrication of Michigan occlusal splints. The objective was to assess whether different digital bite registration techniques influenced the accuracy of…
- Trial name
- AVOAMSDBR (NCT07356622)
- Testing
- Retruded axis position(RAP with) without a digital facebow, Digital face-bow, digital bite registration, digital scanning, Digital facebow, digital bite registration, digital scanning
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College London
Malnutrition
Study to Assess Safety and Efficacy of Kabiven® in Pediatric Patients 2 to 16 Years of Age
Demonstrate the safety and efficacy of Kabiven compared to standard parenteral nutrition (PN) administered via central vein in pediatric patients (2 to 16 years of age) requiring PN to meet nutritional needs.
- Trial name
- NCT03481894
- Testing
- Kabiven®, Compounded standard parenteral nutrition
- Where
- 2 sites in United States
- Sponsor
- Fresenius Kabi
Sedentary Lifestyle
Investigation of the Effects of Clinical Pilates Exercises on Primary Caregivers of Special Needs Children
The aim of this research is to investigate the effectiveness of clinical Pilates exercises applied to primary caregivers of children with special needs, flexibility, muscle strength, endurance, cardiovascular endurance, fatigue…
- Trial name
- NCT03729466
- Testing
- clinical pilates
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Arterial Occlusive Diseases
Study of Alfimeprase to Rapidly Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery on Leg Arteries
The purpose of this study is to directly compare the safety and efficacy of intra-thrombus alfimeprase 0.3 mg/kg with placebo in acute peripheral arterial occlusion (PAO) as measured by a 30 day open vascular free surgery rate.
- Trial name
- NCT00115999
- Testing
- alfimeprase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- ARCA Biopharma, Inc.
Colorectal Cancer
Information Needs After Surgery for Colorectal Cancer
Aim The overall aim was to investigate information needs after surgery for colorectal cancer and factors explaining information needs, both from the patients' perspective and the next of kin's.
- Trial name
- NCT01303393
- Where
- 3 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Region Skane
COVID-19
Passive Immunotherapy In Patients With SARS CoV-2
Plasma from convalescent individuals (convalescent plasma, CP) has been used for more than a hundred years for the treatment of infectious diseases.
- Trial name
- CoV-PlasGal (NCT05578391)
- Testing
- Convalescent plasma
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Atrial Fibrillation (AF), VTE
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure
PAUSE 2 study is a prospective, open-label, blinded-endpoint non-inferiority RCT of PAUSE vs. ASRA management in DOAC treated high risk patients with AF/VTE who need elective high bleed risk surgery/procedure and/or any procedure…
- Trial name
- PAUSE 2 RCT (NCT06957366)
- Testing
- PAUSE Perioperative DOAC Management, ASRA Perioperative DOAC Management
- Where
- 14 sites in United States, Belgium and 2 more
- Volunteers
- 920 people
- Sponsor
- McMaster University
Symptoms and Signs, Artificial Intelligence
BaiXiaoAi AI Companion for Cancer Patient Follow-up
This is a prospective, single-center, exploratory study designed to evaluate the accuracy, user engagement, and user experience of the BaiXiaoAi Companion AI.
- Conditions
- Symptoms and Signs, Artificial Intelligence, Artificial Intelligence Mobile Application, Needs Assessment
- Trial name
- NCT07396142
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 300 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Hip Fractures
Basic Mobility and Physical Activity During Hospitalization for a Hip Fracture: Functions Needed and Strategies Used
Present study aim to gain an understanding of functions needed and strategies used for patients following hip fracture surgery to be independent in basic mobility activities during acute hospitalization, and establish knowledge…
- Trial name
- HIP-ME-UP (NCT05756517)
- Where
- Denmark
- Volunteers
- 101 people
- Sponsor
- Hvidovre University Hospital
Child Development Disorder, Child Development
Investigation of the Usability of the Dynamic Scaffolding System
The aim of the present study was to compare the duration of use of the Dynamic Scaffolding System (DSS) in children with different levels of motor impairment, to report adverse events during use, and to examine parental…
- Conditions
- Child Development Disorder, Child Development, Assistive Technology
- Trial name
- NCT05727046
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Karadeniz Technical University
Oncologic Complications
Patient Intake At the 'MOvement and REhabilitation (MO.RE.)
In recent years, there has been an exponential increase in studies regarding the benefits of physical activity in oncology, with significant results on improving both physical and psychological outcomes.
- Trial name
- BACKMORE2024 (NCT06858241)
- Where
- Italy
- Volunteers
- 95 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Advanced Cancer, Sexual Satisfaction
Assessment of the Quality and Sexual Health Needs of Patients with Advanced-stage Cancer
Sexual health is an important determinant of the overall health of a population, as addressed in the French National Strategy 2017-2030.
- Trial name
- INTIMI-K (NCT06229158)
- Testing
- Sexual satisfaction questionnaire for patients, Sexual satisfaction questionnaire for patients' life partner
- Where
- 3 sites in France
- Volunteers
- 120 people
- Sponsor
- Hospices Civils de Lyon
Immunoglobin M Anti-myelin-associated-glycoprotein Peripheral Neuropathy
Immunoglobulin M (IgM)-Anti-myelin-associated-glycoprotein(MAG) Peripheral Neuropathy Study
There is no international consensus regarding how to assess and treat patients with immunoglobulin M (IgM)-anti-myelin-associated-glycoprotein (MAG) monoclonal gammopathy associated peripheral neuropathy.
- Trial name
- NCT03918421
- Testing
- Clinical examination and patients' questionnaires regarding activity and participation (preliminary Immunogloblin M (IgM)-Rasch-built overall Disability Scale (RODS), and finalized IgM-RODS)
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon
Failed Induction of Labor
Modifying Cervical Bishop Scoring System
To have an early more precise way to predict failed induction in patients undergoing elective termination of pregnancy \& those more likely to undergo caesarian section,this will Spare patients with decreased chances of favorable…
- Trial name
- NCT02314260
- Testing
- bishop score calculation, Trans-vaginal ultrasound, Modified bishop score calculation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital