Clinical trials: Negative Thinking
Intrusive Negative Thinking
Intervention for Intrusive Negative Thinking
Intrusive negative thinking styles such as rumination are typical of many psychiatric disorders, are difficult to treat, and predict poor treatment outcome.
- Trial name
- NCT02394704
- Testing
- Sensory attention training
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of Pittsburgh
Cardiovascular Diseases
Gratitude Intervention for Cardiac Rehabilitation Patients
This is a single-center cohort study of patients in a cardiac rehabilitation program with a diagnosis of cardiovascular disease (CVD), including heart failure, coronary artery disease, post myocardial infarction, post…
- Trial name
- NCT04314583
- Testing
- Attention Control, Gratitude Journaling
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Martha Biddle
Depressive Disorder, Major
Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression
In this project, the investigators use real-time fMRI neurofeedback (rtfMRI-nf) to causally relate dysfunction of right anterior insula (rAI) and right superior temporal sulcus (rSTS) connectivity with the intensity of repetitive…
- Trial name
- CNF-RNT (NCT06219681)
- Testing
- Active neurofeedback
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts
Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts
The goal of this [type of study: exercise intervention study] is to test in describe participant health conditions. The main questions it aims to answer are: [Whether physical exercise improves executive function of male heroin…
- Conditions
- Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts, Executive Function, Negative Thinking/Affect
- Trial name
- NCT05650983
- Testing
- Aerobic exercise; Resistance exercise
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangzhou Sport University
Stress, Anxiety
A Brief Online Mindfulness Intervention: An RCT Protocol
University students often experience emotional distress that originates from inside or outside academia, and for which treatment would be welcome.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT05882565
- Testing
- A brief (14-day) online mindfulness intervention, Psychoeducation online
- Where
- Indonesia
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Ka Yan
Stress, Stress Disorders
Manage Your Workingnegative Thoughts Through Hypnosis
Medical doctor generally are exposed to several risks and pressures, it is not a case that several meta-analyses have shown high stress and anxiety level in these workers. Stress management represents a very important topic.
- Trial name
- Hypnosis (NCT06778109)
- Testing
- Experimental: Hypnosis and negative memory
- Where
- 2 sites in Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Padova
Schizophrenia
A Study of RO4917838 in Combination With Antipsychotic Treatment in Patients With Schizophrenia.
This study will determine the efficacy and safety of RO4917838 in patients with schizophrenia who are stable on current antipsychotic treatment (olanzapine, que tiapine, risperidone, paliperidone or aripiprazole) with prominent…
- Trial name
- NCT00616798
- Testing
- RO4917838, Standard antipsychotic therapy
- Where
- 73 sites in United States, Austria and 8 more
- Volunteers
- 323 people
- Sponsor
- Hoffmann-La Roche
Eating Disorder Symptom, Emotional Maladjustment
Testing if Reductions in Negative Affect Yield Decreased Emotional Eating Symptoms
The purpose of this study to test a computerized treatment designed to help people with high levels of emotional eating, which is when people eat to cope with negative emotions and/or stressful situations.
- Conditions
- Eating Disorder Symptom, Emotional Maladjustment, Negative Thoughts
- Trial name
- NCT03040076
- Testing
- Cognitive Bias Treatment, Relaxation Condition
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Florida State University
Depression, Rumination - Thoughts
Evaluating a Mobile Phone Intervention
This clinical trial intends to study the efficacy of a mobile phone delivered intervention in reducing depression-related rumination.
- Trial name
- NCT04554706
- Testing
- Mobile-phone delivered Treatment for Excessive Rumination
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Repetitive Negative Thinking, Healthy Controls Group - Age and Sex-matched
Emotion Regulation in RNT
The goal of this study is to understand why some people become stuck in repetitive negative thinking, which is common among individuals with depression and anxiety.
- Trial name
- NCT07513766
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Anxiety Disorders, Obsessive-Compulsive Disorder
Relationship Between Repetitive Negative Thinking and CBT Outcomes
The goal of this observational study is to learn about the role of repetitive negative thinking (measured by the RTQ) in adult populations from an anxiety disorders and trauma clinic.
- Conditions
- Anxiety Disorders, Obsessive-Compulsive Disorder, Post-traumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- NCT06370559
- Where
- United Kingdom
- Volunteers
- 320 people
- Sponsor
- South London and Maudsley NHS Foundation Trust
Rumination, Worry
Evaluating the Effects of a Self-help Mobile Phone Application on Worry and Overthinking in Young Adults Aged Between 16 and 24.
This project seeks to understand if a new self-help mobile phone application (called MyMoodCoach) is effective at reducing worry and overthinking, prominent risk factors that predict reduced well-being and poor mental health.
- Conditions
- Rumination, Worry, Repetitive Negative Thinking
- Trial name
- NCT04950257
- Testing
- digital CBT self-help including specific intervention elements to target worry and rumination.
- Where
- United Kingdom
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Repetitive Negative Thinking, General Anxiety Disorder
Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission
Repetitive negative thinking (RNT) plays an important role in different psychiatric disorders, such as depressive and anxiety disorders, complicated grief, posttraumatic stress disorders, anorexia nervosa.
- Conditions
- Repetitive Negative Thinking, General Anxiety Disorder, Depressive Disorder, Depression
- Trial name
- Drop It (NCT01983033)
- Testing
- Drop It training session, treatment as usual
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Body Dissatisfaction
Singing Your Negative Body-Related Thoughts
Study Objectives: 1. Examine whether singing can be used as a cognitive defusion strategy to change one's appraisals of body-related thoughts so they are less threatening to the individual. 2.
- Trial name
- NCT03646305
- Testing
- Cognitive Defusion
- Where
- Canada
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- York University
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts
The investigators are conducting this study to learn more about the cognitive and attentional processes among individuals with three types of repetitive negative thinking (RNT): mental rituals (as seen in obsessive compulsive…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT04225624
- Testing
- Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder
Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression
The investigators propose to use low-intensity transcranial focused ultrasound (LIFU), a novel neuromodulation method, to probe the causal involvement of individually defined components of an anteromedial brain circuit in the…
- Trial name
- NCT05697172
- Testing
- Low-intensity focused ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Attention Impaired, Mental Health Issue
Brief Mental Training and Internal Attentional Control
Previous research documented that real-time feedback on attention as well as related forms of mental training (e.g. mindfulness meditation) may be used to train and impact external attentional control.
- Conditions
- Attention Impaired, Mental Health Issue, Rumination
- Trial name
- NCT05353231
- Testing
- Attention Feedback Awareness and Control Training (A-FACT), Mindful Disengagement from Thoughts Training (MDTT)
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Diabetes Mellitus, Type 2
Perceived Stress and Negative Thoughts With Biomarkers in People With Type 2 Diabetes Mellitus and Healthy Subjects
The purpose of this study is to determine the effect of measured and induced negative feelings on glucose, tumor necrosis factor alpha, and cortisol levels in healthy participants and participants with type 2 diabetes mellitus.
- Trial name
- NCT04387045
- Testing
- Guilty feelings
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Carlos López Marquez