Clinical trials: Neisseria Gonorrheae Infection
HIV, Syphilis
Texting Intervention to Sustain HIV Prevention in Women in High-drug-use Contexts
The purpose of this study is to determine whether a program of regular, theory-based text messages that encourages the message recipient to continue practicing safer sex (i.e., using condoms with sex partners) is effective in…
- Conditions
- HIV, Syphilis, Gonorrhea, Chlamydia
- Trial name
- NCT02447484
- Testing
- Mujer Segura Siempre, General Health Message Texts
- Where
- Mexico
- Volunteers
- 600 people
- Sponsor
- University of California, San Diego
Sexually Transmitted Diseases, Syphilis
Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de Janeiro
The goal of this clinical trial is to learn if doxycycline post-exposure prophylaxis (doxy-PEP) can help prevent bacterial sexually transmitted infections (STIs) among sexual and gender minorities in Rio de Janeiro, Brazil…
- Conditions
- Sexually Transmitted Diseases, Syphilis, Gonorrhea, Chlamydia Infections
- Trial name
- NCT07500415
- Testing
- Doxycycline
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Syphilis, Gonorrhea
Lay Health Advisors for Sexually Transmitted Disease Prevention
Non-professional community leaders may be at a great advantage in reaching otherwise hard to reach populations for the purpose of advising on sexually transmitted disease (STD) prevention (lay health advisors), health care…
- Conditions
- Syphilis, Gonorrhea, Chlamydia Infections, HIV Infections
- Trial name
- NCT00207506
- Testing
- HoMBReS: A lay health advisor approach to STD prevention
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Gonorrhea
Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoea
A non-inferiority, open-label, multicentre randomised controlled trial to compare two therapeutic regimens for the treatment of uncomplicated urogenital, rectal or pharyngeal gonorrhoea in men and women between 18 and 75 years of…
- Trial name
- NCT06090565
- Testing
- Cefixime, Doxycyclin, Ceftriaxon
- Where
- 2 sites in Czechia
- Volunteers
- 161 people
- Sponsor
- Bulovka Hospital
Electrocardiogram Repolarisation Abnormality, Gonococcal Infection
Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects
The Phase I Thorough QT/QTc (TQT) study will be performed in a single center, the Vince \& Associates Clinical Research, Inc., clinical trials unit (CTU), in 72 healthy male or female subjects, aged 18 to 45 years inclusive, to…
- Trial name
- NCT03613649
- Testing
- AZD0914, Moxifloxacin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Neisseria Gonorrhea, Trichomoniasis Vaginalis
Acceptability Research on Integrated Point of Care Sexually Transmitted Infection (STI) Testing and Expedited Partner Therapy (EPT)
This protocol builds on nearly a decade of collaborative HIV/STI prevention research to conduct a prospective cohort study of Adolescent Girls and Young Women (AGYW) eligible for PrEP in South Africa in which we will assess the…
- Conditions
- Neisseria Gonorrhea, Trichomoniasis Vaginalis, Chlamydia Trachomatis Infection
- Trial name
- ARISE (NCT06570733)
- Where
- South Africa
- Volunteers
- 305 people
- Sponsor
- Wits RHI Research Centre Clinical Research Site
Sexually Transmitted Diseases
Safety and Efficacy of GSK Neisseria Gonorrhoeae GMMA (NgG) Investigational Vaccine When Administered to Healthy Adults 18 to 50 Years of Age
The aim of this first time in human proof of concept (FTiH-PoC) study was to evaluate safety and reactogenicity, to demonstrate efficacy and to explore immunogenicity of GlaxoSmithKline's (GSK) Neisseria gonorrhoeae generalized…
- Trial name
- NCT05630859
- Testing
- NgG 12.5 µg investigational vaccine, NgG 25 µg investigational vaccine, NgG 50 µg investigational vaccine
- Where
- 23 sites in United States, Brazil and 6 more
- Volunteers
- 1,009 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gonococcal (GC) Infection
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD0914
The purpose of this study is to assess the safety and tolerability of orally administered AZD0914 in healthy adult subjects.
- Trial name
- NCT01929629
- Testing
- Part A, Part B
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Gonorrhea
Comparison of Delafloxacin Versus Ceftriaxone for the Treatment of Uncomplicated Gonorrhea
The purpose of this study is to evaluate the effects of a single oral dose of delafloxacin versus a single intramuscular injection of ceftriaxone in subjects with uncomplicated cervical, urethral, rectal, or pharyngeal gonorrhea.
- Trial name
- NCT02015637
- Testing
- Delafloxacin, Ceftriaxone
- Where
- 25 sites in United States
- Volunteers
- 460 people
- Sponsor
- Melinta Therapeutics, Inc.
Gonorrhea, Gonorrhea of Pharynx
BIYELA - Bexsero Immunisation in Young Women in Africa
This proposed 2-arm randomized evaluation of two doses of 4CMenB vaccine versus placebo at Enrollment and Month 2 is designed as a proof-of-concept study to inform potential use for dual meningococcal B and gonococcal prevention…
- Conditions
- Gonorrhea, Gonorrhea of Pharynx, Gonorrhea of Anus, Gonorrhea of Cervix
- Trial name
- NCT06446752
- Testing
- Bexsero
- Where
- 5 sites in South Africa
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sexually Transmitted Diseases, Gonorrhea
Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening
In the United States (US), gay and bisexual men living with human immunodeficiency virus (HIV) bear a heavy burden of bacterial sexually transmitted infections (STIs) such as gonorrhea, chlamydia, and syphilis.
- Conditions
- Sexually Transmitted Diseases, Gonorrhea, Chlamydia, Syphilis
- Trial name
- NCT06100250
- Testing
- Motivational interviewing and specimen self-collection
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Michigan
Gonococcal (GC) Infection, Arthritis, Infectious
Epidemiology of Gonococcal Arthritis (EpGAr)
The aim of this retrospective observational study was to describe the epidemiology of Neisseria gonorrhoeae septic arthritis over the last 10 years at Brest and Rennes university hospitals.
- Trial name
- EpGAr (NCT06897943)
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Brest
Gonorrhoea
Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin
This is an open-label Phase I study of plasma, genitourinary, rectal, and pharyngeal pharmacokinetics of a single 1000mg oral dose of solithromycin.
- Trial name
- NCT02348424
- Testing
- Solithromycin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gonorrhea
A Study Evaluating Efficacy and Safety of CRO-SBT in the Treatment of Gonorrhea
This is a phaseIV, multicenter, open-label，single arm study which will be performed to evaluate efficacy and safety of Ceftriaxone sodium and Sulbactam Sodium for injection for the treatment of uncomplicated urogenital infection…
- Trial name
- CRO-SBT (NCT04202068)
- Testing
- Ceftriaxone sodium and Sulbactam Sodium for injection
- Volunteers
- 113 people
- Sponsor
- Xiangbei Welman Pharmaceutical Co., Ltd
Gonorrhea, Chlamydia
A Study to Learn About How Trumenba Vaccine Shots Work Against Gonorrhea Infection in Teenagers and Young Adults in the United States.
Brief Summary: The main purpose of the study is to learn about how well Trumenba vaccine shot works against gonorrhea infection. This study looks at data records from a database in the United States.
- Conditions
- Gonorrhea, Chlamydia, Meningococcal Vaccines
- Trial name
- NCT05873751
- Testing
- Trumenba Vaccine, MenACWY Vaccine
- Where
- United States
- Volunteers
- 1,307,378 people
- Sponsor
- Pfizer
Human Immunodeficiency Virus, Herpes Simplex Type II
MAMAS: Mentoring Adolescent Mothers at School
This study aims to evaluate the efficacy of an intervention designed to reduce STI/HIV incidence by increasing the number of adolescent mothers who re-enroll and remain in school.
- Conditions
- Human Immunodeficiency Virus, Herpes Simplex Type II, Chlamydia, Gonorrhea
- Trial name
- MAMAS (NCT03090802)
- Testing
- Mentoring Adolescent Mothers at School (MAMAS)
- Where
- South Africa
- Volunteers
- 152 people
- Sponsor
- Drexel University
Chlamydia Infections, Gonorrhea
Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays
The objective of this study is to obtain female first-catch urine, vaginal, cervical and endocervical swabs for testing with multiple APTIMA Assays on the Gen-Probe PANTHER® and TIGRIS® Systems.
- Conditions
- Chlamydia Infections, Gonorrhea, Trichomonas Infections
- Trial name
- NCT01728103
- Testing
- APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
- Where
- 14 sites in United States
- Volunteers
- 1,336 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
NeuMoDx PrEDiCTiNG Study Evaluation Plan
This investigational study will be conducted to evaluate the performance of the NeuMoDx™ CT/NG Assay on the NeuMoDx™ 288 Molecular System and NeuMoDx™ 96 Molecular System (collectively referred to as NeuMoDx™ CT/NG Assay test…
- Trial name
- NCT03970850
- Testing
- NeuMoDx CT/NG Assay, FDA-cleared NAATs
- Where
- 15 sites in United States
- Volunteers
- 4,017 people, healthy volunteers welcome
- Sponsor
- NeuMoDx Molecular, Inc.
Sexually Transmitted Infections (Not HIV or Hepatitis), Chlamydia Trachomatis Infection
Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST)
The main objective of the study will be to assess the performance of the Next-Generation-Sequencing (NGS) diagnostics of Chlamydia trachomatis and Neisseria gonorrhoeae compared to reference techniques.
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection
- Trial name
- NGS-IST (NCT05581160)
- Testing
- Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST)
- Where
- 2 sites in France
- Volunteers
- 332 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Chlamydia, Gonorrhea
Randomized Trial of Home Versus Clinic-Based STD Testing
This study randomizes St. Louis men to home-based STD screening or clinic-based STD screening. Home-based screening will be completed through the mail and clinic-based screening in a local clinical setting.
- Trial name
- NCT01654991
- Testing
- Home Screening, Clinic Screening
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)