Clinical trials: Neonatal Adaptation
Stroke, Spinocerebellar Ataxia
Laryngeal Adaptation for Speech and Swallowing
This study will test laryngeal adaptation in speech and swallowing function in healthy adults, in patients with cerebral stroke, and in patients with spinocerebellar ataxia type 6.
- Conditions
- Stroke, Spinocerebellar Ataxia, Cerebral Stroke, Dysphagia
- Trial name
- NCT03770377
- Testing
- Intermittent Perturbation to Continuous Perturbation, Continuous Perturbation to Intermittent Perturbation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Haematological Malignancy, Acute Leukemia
A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts
To date, allogeneic haematopoietic stem cell transplantation (aHSCT) is the only curative treatment for many paediatric and young adult haematological pathologies (acute leukaemia, myelodysplastic syndromes, haemoglobinopathies…
- Conditions
- Haematological Malignancy, Acute Leukemia, Myelodysplastic Syndromes, Hemoglobinopathy in Children
- Trial name
- EVAADE (NCT04331483)
- Testing
- Physical activity program
- Where
- France
- Sponsor
- Centre Leon Berard
Wet Lung
Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn
In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the…
- Trial name
- NCT01149928
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Takayasu Arteritis, Behcet Disease
Turkish Adaptation of the VascuQoL-6 Quality of Life Scale
Study type: Observational study Primary objective: The aim of this study was to examine the validity and reliability of the Vascular Quality of Life Questionnaire-6 (VascuQoL-6) in Turkish in individuals diagnosed with Takayasu…
- Conditions
- Takayasu Arteritis, Behcet Disease, Quality of Life
- Trial name
- NCT06979245
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Uşak University
Intermittent Urethral Catheterization, Spinal Dysraphism
The Effect of Nursing Interventions for Clean Intermittent Catheterization Caregivers and Child
In neurogenic or non-neurogenic bladder disorders, the removal process after the catheter is inserted into the bladder and the urine has been drained is called Clean intermittent catheterization (CIC).
- Conditions
- Intermittent Urethral Catheterization, Spinal Dysraphism, Urinary Tract Infections
- Trial name
- NCT04763382
- Testing
- experimental group: Training of caregivers, Control gruop
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Adult Acute Basophilic Leukemia, Adult Acute Eosinophilic Leukemia
Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemia
Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PSC 833 may increase the effectiveness of chemotherapy by making cancer cells more sensitive to the drugs.
- Conditions
- Adult Acute Basophilic Leukemia, Adult Acute Eosinophilic Leukemia, Adult Acute Erythroid Leukemia (M6), Adult Acute Megakaryoblastic Leukemia (M7)
- Trial name
- NCT00006363
- Testing
- cytarabine, daunorubicin hydrochloride, etoposide
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- National Cancer Institute (NCI)
Neurodegenerative Diseases, Leukodystrophy
Home Exercise for Individuals With Neurodegenerative Disease
The primary goal of this study is to address the need for targeted therapeutic interventions for impairments that impact walking in related neurodegenerative diseases.
- Conditions
- Neurodegenerative Diseases, Leukodystrophy, Ataxia, LBSL
- Trial name
- NCT05443906
- Testing
- Home exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Health-related Quality of Life, Dentofacial Deformities
Cross Cultural Adaptation and Validation of Orthognathic Quality of Life Questionnaire (OQLQ)
The aim of this study was to develop a Spanish version of the Orthognathic Quality of Life Questionnaire (OQLQ) that is conceptually equivalent to the original questionnaire, as well as acceptable, reliable, valid, and responsive…
- Trial name
- NCT04863170
- Testing
- orthognathic surgery
- Where
- Chile
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospital Carlos Van Buren
DSD, Hypospadias
Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions
The goal of this clinical trial is to learn whether a journaling intervention can reduce stress and anxiety in parents of children with urogenital conditions (such as differences of sex development and hypospadias).
- Trial name
- NCT06989593
- Testing
- Narrative Medicine Journaling Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sarah Schlegel
Duchenne Muscular Dystrophy, Ambulation Difficulty
Cultural Adaptation, Validity, and Reliability of the Turkish Version of North Star Ambulatory Assessment
The aim of this study is to translate the "North Star Ambulatory Assessment (NSAA)" scale into Turkish and make its cultural adaptation and to demonstrate the reliability and validity of the Turkish version in patients with…
- Conditions
- Duchenne Muscular Dystrophy, Ambulation Difficulty, Ambulation Disorder, Neurologic
- Trial name
- NCT05549999
- Testing
- North Star Ambulatory Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Hacettepe University
Neonatal Adaptation
Defining Reference Ranges for Cerebral Oxygenation In Neonates (COIN) During Immediate Neonatal Transition After Birth
Especially in neonates non-invasive methods are required for monitoring the complex changes during immediate transition after birth to improve assessment of neonate and eventually resuscitation.
- Trial name
- COIN (NCT04594824)
- Testing
- No Intervention
- Where
- Austria
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Pregnancy
Evaluation of a Decision Assisting Tool for Prenatal Testing
This is a randomized study of an interactive, computerized descision-assisting tool for prenatal testing decision making (PT Tool) versus standard educational booklets distributed to all pregnant women by the State of California…
- Trial name
- NCT00686062
- Testing
- Control - computerized age-appropriate prenatal testing educational brochure, PT Tool - interactive, computerized, prenatal testing decision tool
- Where
- United States
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fetal Growth Retardation
Study Aimed At Improving Height With Genotonorm In Children Born Little And/Or Light With Growth Retardation At The Age
To estimate the percentage of children with serum IGF-1 > 2 standard deviation (compared to a child of the same gender and age and without growth hormone (GH) deficiency) 9 months and 12 months after initiation of GH treatment.
- Trial name
- NCT00174252
- Testing
- Genotonorm (Somatropin)
- Where
- 22 sites in France
- Volunteers
- 57 people
- Sponsor
- Pfizer
Parents of Healthy Newborns, Pregnant Women and Partners
French Cross-cultural Adaptation of the Iowa Infant Feeding Attitude Scale (IIFAS)
Our study will consist of two parts: Part 1: Cross-cultural adaptation of the Iowa Infant Feeding Attitude Scale (IIFAS) among postpartum mothers and co-parents in France and assessment of its psychometric properties Part 2…
- Trial name
- FRENCH IIFAS (NCT07620704)
- Where
- France
- Volunteers
- 930 people
- Sponsor
- University Hospital, Clermont-Ferrand
Adipocytic Neoplasm, Liposarcoma
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
The study participant has been diagnosed with non-rhabdomyosarcoma (NRSTS). Primary Objectives Intermediate-Risk To estimate the 3-year event-free survival for intermediate-risk patients treated with ifosfamide, doxorubicin…
- Conditions
- Adipocytic Neoplasm, Liposarcoma, Atypical Fibroxanthoma, Angiomatoid Fibrous Histiocytoma
- Trial name
- NCT06239272
- Testing
- Surgical resection, Proton beam radiation therapy, Pazopanib
- Where
- 7 sites in United States
- Volunteers
- 139 people
- Sponsor
- St. Jude Children's Research Hospital
Depressive Disorder, Lactation
Antidepressants During Pregnancy and Lactation: Pharmacokinetics and Clinical Implications
Background: The childbearing years are a time of increased vulnerability to the onset of mood disorders in women and a high prevalence of exposure to antidepressant drugs during pregnancy and postpartum has been reported.
- Trial name
- NCT01796132
- Testing
- SSRI/SNRI
- Where
- 5 sites in France, Switzerland
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Osteogenesis Imperfecta
Evaluation of the Benefits of Adaptive Physical Activity in Children and Adolescents With Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is a rare genetic disorder of increased bone fragility and low bone mass. It is conceivable that children and adolescents with OI are less active than healthy peers because of frequent fractures…
- Trial name
- MOVE-OI (NCT04119388)
- Testing
- Adapted sports practices
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Antipsychotics, Pregnancy
Maternal And Infant Antipsychotic Study
The goal of this observational study is to learn about maternal psychiatric course and infant development in pregnant individuals with severe mental illness, comparing those treated with antipsychotics to those treated with other…
- Trial name
- MAIA (NCT06049953)
- Testing
- Antipsychotics, Non-antipsychotic medication, No Medication
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Klinefelter Syndrome
Adaptation Among Adolescents and Adults With Klinefelter Syndrome
This study aims to understand the impact of living with Klinefelter syndrome (KS) and the factors that contribute to adaptation in adolescents and adults.
- Trial name
- NCT00896272
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Pain
Translation and Cross-Cultural Adaptation Into French of the COMFORTneo Pain Assessment Tool for Newborns
Observational pain assessment scales are essential for the management of pain in young children, particularly in newborns. Numerous observational pain assessment scales for newborns and preterm infants exist worldwide; however…
- Trial name
- TradNeo (NCT07463170)
- Testing
- Expert committee, Pre test
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris