Clinical trials: Neonatal Care
Critical Illness
Clinical Trial on Individual Characteristics Affecting Pain Drug Therapy in Neonates
Children differ from adults with respect to growth and development but also immaturity of various pharmacological mechanisms. Dosing schemes in children are usually derived in an empirical manner from clinical trials in adult…
- Trial name
- NeoPopGen (NCT02426463)
- Testing
- propofol, oxycodone
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Turku University Hospital
Abdominal Pain, Gallstone; Colic
RELIEF-pathway in Patients With Upper Abdominal Pain
Upper abdominal pain (UAP) is a common symptom and frequently the reason to visit the hospital. The prevalence of epigastric pain in the Dutch population is estimated to be as high as 37%.
- Conditions
- Abdominal Pain, Gallstone; Colic, Dyspepsia, Irritable Bowel Syndrome
- Trial name
- RELIEF (NCT06002516)
- Testing
- RELIEF-pathway
- Where
- Netherlands
- Volunteers
- 471 people
- Sponsor
- Radboud University Medical Center
Kidney Failure, Chronic
Effect of Exercise on Endothelial Function and Vascular Compliance in Chronic Kidney Disease
The study hypothesis is that 6 weeks of repetitive handgrip exercise will improve endothelial function and venous compliance in pre-dialysis patients with an estimated glomerular filtration rate of less than or equal to 20…
- Trial name
- NCT01068314
- Testing
- Repetitive arm exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Iowa
Hemophilia B, Hemophilia A
A Study to Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adult Hemophilia B Subjects (FIX:C≤2%) or Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Subjects (FVIII:C≤1%)
To establish baseline prospective efficacy data of current FIX prophylaxis replacement therapy in the usual care setting of hemophilia B subjects, who are negative for nAb to AAV-Spark100, prior to the Phase 3 gene therapy study.
- Trial name
- NCT03587116
- Testing
- Standard of Care FIX Replacement therapy, Standard of Care FVIII Replacement therapy
- Where
- 75 sites in United States, Australia and 16 more
- Volunteers
- 212 people
- Sponsor
- Pfizer
Preterm Birth, Premature Birth
Exposure to Plasticisers in the Neonatal Intensive Care Unit
Neonatal intensive care relies on indwelling plastic medical devices fundamental in respiratory support, intravenous catheterization, and nutrition.
- Conditions
- Preterm Birth, Premature Birth, Neurodevelopmental Disorders, Pulmonary Disease
- Trial name
- PLASTIC-NICU (NCT05404815)
- Where
- Belgium
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Heart Defects, Congenital, Intensive Care Units, Pediatric
High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery
High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery
- Conditions
- Heart Defects, Congenital, Intensive Care Units, Pediatric, Respiration, Artificial, Extubation
- Trial name
- NCT07059689
- Testing
- High Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
- Where
- Indonesia
- Volunteers
- 114 people
- Sponsor
- Universitas Indonesia
Infant, Premature, Diseases, Respiratory Disease
Critical Respiratory Diseases in Ex-preterm Infants in PICU
Premature birth is the leading cause of death in children younger than 5 years old worldwide, especially in low- and middle-income countries.
- Conditions
- Infant, Premature, Diseases, Respiratory Disease, Respiratory Failure, Premature Birth
- Trial name
- NCT04284891
- Where
- Vietnam
- Volunteers
- 202 people
- Sponsor
- National Children's Hospital, Vietnam
Length of Stay
Discharge Criteria of Preterm Infants
This retrospective study aims to compare discharge criteria and their impact on the length of stay using two neonatal intensive care units from two countries.
- Trial name
- NCT06144190
- Where
- Japan
- Volunteers
- 71 people
- Sponsor
- Nagano Children's Hospital
Care
Effect of Care Package on Duration of Stay and Physiological Parameters in Non-invasive Mechanical Ventilation
Temporary tachypnea of the newborn can be improved with minimal respiratory support and nursing care given to babies within the first 72 hours of life.
- Trial name
- NCT06189989
- Testing
- The group to which a care package was applied in addition to the clinical routine care protocol)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Okan University
Neonates, Infants Aged 0 Days to 12 Months Scheduled for Elective Surgery
Upper Airway Ultrasound to Predict Difficult Laryngoscopy in Neonates and Infants
Upper airway ultrasound (UA-US) has been utilized in adults to predict difficult laryngoscopy (Cormick-Lehane view 3 or 4) and difficult tracheal intubation (DTI) (≥3 intubation attempts) and with moderate-to-high sensitivity and…
- Trial name
- NCT07444528
- Testing
- Upper airway ultrasound
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Premature Birth, Birth Weight
Fresh RX: NHS 2020
This study is an evaluation of the Fresh Rx: Nourishing Healthy Starts program administered by Operation Food Search, a St. Louis-based nonprofit organization.
- Conditions
- Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization
- Trial name
- NCT04845230
- Testing
- FreshRx Nourishing Healthy Starts
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed
Durham Connects RCT Evaluation II
The aim of this randomized controlled trial (RCT) is to conduct a second, independent evaluation the implementation and impact of the Durham Connects (DC) brief universal nurse home-visiting program to prevent child maltreatment…
- Trial name
- NCT01843036
- Testing
- Durham Connects
- Where
- United States
- Volunteers
- 1,650 people
- Sponsor
- Duke University
Breastfeeding, Motivation
The Effect of Motivational Interviewing-Based Breastfeeding Education on Breastfeeding Motivation and Self-Efficacy
This study is being conducted to examine the effect of a motivational interviewing-based breastfeeding education intervention provided to mothers whose infants are hospitalized in the neonatal intensive care unit on the mothers'…
- Conditions
- Breastfeeding, Motivation, Self Efficacy
- Trial name
- NCT06623292
- Testing
- Motivational interviewing-based breastfeeding education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Congenital Heart Disease (CHD), Screening Tool
"SOUND" Trial: Study of On-site Use of Novel AI-assisted Diagnostics in CHD Screening
This study plans to conduct clinical validation of the model in real clinical settings, comparing it with primary care physicians and specialist physicians to ensure the model's practicality.
- Conditions
- Congenital Heart Disease (CHD), Screening Tool, Artificial Intelligence (AI), Cluster Randomized Trial
- Trial name
- NCT06791109
- Testing
- Primary care physicians, AI + Primary care physicians
- Where
- China
- Volunteers
- 19,697 people, healthy volunteers welcome
- Sponsor
- Kun Sun
Diaper Rash, Preterm Neonates
Colloidal Oatmeal, Colloid Cream, Diaper Rash, Preterm Neonates and Neonatal Intensive Care Unit
-This study aimed to investigate the effect of colloid oatmeal compared to colloid cream on diaper rash among preterm neonates in the NICU.
- Trial name
- NCT05892081
- Testing
- Colloidal oatmeal, Cold cream
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Seham El-Sayed Saleh Hassan
ADPKD
Genetic Testing in Autosomal Dominant Polycystic Kidney Disease
Individuals with a diagnosis of autosomal dominant polycystic kidney disease (ADPKD) often have a family history of the condition although up to 10-15% of cases are sporadic mutations.
- Trial name
- NCT06085807
- Testing
- Survey
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fetal Death, Fetal Anomaly
Antenatal Palliative Care
In France, according to current legislation, termination of pregnancy could be performed without any upper gestational age limit, if there is a strong probability that the fetus will be affected by a particularly severe and…
- Trial name
- SPAN (NCT03795857)
- Testing
- Semi-structured interviews
- Where
- 3 sites in France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Infant, Newborn, Weight Loss
Effect of Kangaroo Care on Phyiological Weight Loss in Term Newborns
The aim of the study is to evaluate the effect of kangaroo care on physiological weight loss in term newborns.
- Trial name
- NCT05001334
- Testing
- Kangaroo care training
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Malaria
Lapdap and Coartemether for Uncomplicated Malaria
Lapdap (chlorproguanil-dapsone) is an affordable and effective drug, but patients with glucose-6-phosphate dehydrogenase (G6PD) A- deficiency are more susceptible to the haemolytic effects of the dapsone component of Lapdap…
- Trial name
- NCT00118794
- Testing
- Chlorproguanil-dapsone (Lapdap), Lumefantrine-artemether (Coartemether )
- Where
- The Gambia
- Volunteers
- 1,200 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Gout
Arthritis Research UK Gout Treatment Trial - Phase 2
The purpose of this study is to determine in community-derived patients with gout the effectiveness, and cost effectiveness, of a nurse-led complex intervention that reflects recommended best practice (including patient…
- Trial name
- NCT01477346
- Testing
- Nurse intervention, Standard care
- Where
- United Kingdom
- Volunteers
- 517 people
- Sponsor
- University of Nottingham