Clinical trials: Neonatal Health
Coronary Artery Bypass Grafting, Heart Valve Disease
LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients
This is a single-center, prospective, randomized, open-label, parallel-controlled clinical study to evaluate the effectiveness of a large language model (LLM)-based intelligent health management assistant in the life-cycle health…
- Conditions
- Coronary Artery Bypass Grafting, Heart Valve Disease, Aortic Aneurysm, Aortic Dissection
- Trial name
- cFT-LLM (NCT07521488)
- Testing
- LLM-Based Intelligent Health Management Assistant
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Anzhen Hospital
Cystic Fibrosis
Improving the Well-being of Caregivers of Cystic Fibrosis Patients During Physiotherapy Treatment
The main objective of the study is to determine the impact of cystic fibrosis affecting a child on the parents' quality of life, their possible anxiety and depressive symptoms, their general fatigue and the feeling of burden in…
- Trial name
- MucoZar (NCT06327802)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Pole Sante Grace de Dieu
Skin Abnormalities, Newborn
The NEWBORN SKIN ASSESSMENT ATTITUDE SCALE
The protection of the body integrity of the newborn is very important in terms of the development of physical and mental health and social health.
- Conditions
- Skin Abnormalities, Newborn, Attitude of Health Personnel
- Trial name
- NCT04934254
- Testing
- Attitude Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Cystic Fibrosis
Changes in Adherence After Playing "My Life With CF" Game
Nonadherence to treatment regimes among patients with cystic fibrosis (CF) is well documented in the literature. Unfortunately, few interventions have been successful at improving adherence rates in this patient population.
- Trial name
- NCT00688051
- Testing
- My Life with CF game
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Cystic Fibrosis in Children
Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis
The aim of the present study is to investigate the effect of probiotic supplementation on GI related quality of life, through a randomised placebo-controlled clinical trial.
- Trial name
- NCT06284577
- Testing
- Multistrain Probiotic
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Cystic Fibrosis, Parenthood Status
Health Outcomes of Parents With Cystic Fibrosis-Aim 2
The goal of this observational prospective study is to determine the health impact of parenthood on United States (US) people with CF in the era of CF transmembrane regulator protein (CFTR) modulators.
- Trial name
- HOPeCF (NCT06296394)
- Testing
- Parenthood
- Where
- 18 sites in United States
- Volunteers
- 146 people
- Sponsor
- University of Pittsburgh
Down Syndrome, Health, Subjective
Developing a Down Syndrome Health Instrument
Although over 200,000 individuals with DS live in the United States, studies to date have focused on outcomes apart from health.
- Trial name
- NCT04631237
- Testing
- Observational, no intervention
- Where
- United States
- Volunteers
- 758 people
- Sponsor
- Massachusetts General Hospital
Neurofibromatosis
Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NF
This is a prospective study through the NF clinic at Massachusetts General Hospital that will examine the relationship between psychosocial factors, health literacy, and satisfaction with the medical visit in adults with NF1…
- Trial name
- NCT02435628
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hereditary Breast and Ovarian Cancer, Lynch Syndrome
Scalable Communication Modalities for Returning Genetic Research Results
Efforts to examine the utility of alternate modalities for genetic results disclosure has widespread implications for how precision medicine research might yield direct health benefits for study participants.
- Trial name
- BWHS RoR (NCT04407611)
- Testing
- Online modality, Genetic counselor follow-up
- Where
- United States
- Volunteers
- 926 people
- Sponsor
- Boston University
Atopic Dermatitis
Mind and Skin - the Neurocutaneous Axis in Atopic Eczema
'Mind and Skin': A prospective cohort study evaluating the impact of inflammation, itch and sleep disturbance on the brain, mental health and cognition, in patients with severe atopy.
- Trial name
- NCT05790330
- Testing
- Methotrexate, Dupilumab
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- King's College London
Cystic Fibrosis
General Health, Attitudes, and Activity in Self-directed Exercise in Patients With Cystic Fibrosis (GAINS-CF)
Exercise helps people with CF lead long, fulfilling lives. Regular exercise reduces depression and fatigue, and may play a role in preventing exacerbation.
- Trial name
- GAINS-CF (NCT04882267)
- Testing
- Team and Technology
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Malaria,Falciparum, Malaria in Pregnancy
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics
The purpose of the INTREPiD study is to compare 1st trimester screening for malaria parasites with a high-sensitivity malaria rapid diagnostic test followed by treatment of test-positive women with artemether-lumefantrine (AL)…
- Conditions
- Malaria,Falciparum, Malaria in Pregnancy, Malaria in Childbirth, Pregnancy
- Trial name
- INTREPiD (NCT05757167)
- Testing
- Malaria High-Sensitivity Rapid Diagnostic Test (HS-RDT), Artemether-lumefantrine (AL)
- Where
- 2 sites in Democratic Republic of the Congo, Kenya
- Volunteers
- 2,174 people
- Sponsor
- Duke University
Neonatal Meningitis
Epidemiology, Treatment and Prognosis of Neonatal Meningitis in Turkey: A Multicenter Study
Meningitis, defined as inflammation of the meninges caused by different pathogens, is a serious infection associated with high morbidity and mortality. It occurs more commonly in the neonatal period than in any other age group.
- Trial name
- NEO-MENINGITIS (NCT04009551)
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Development of a Tool to Assess the Level of Implementing the European Standards of Care for Newborn Health, Testing of the Developed Self-assessment Tool in European Hospitals
Self-assessment Tool for Implementing the ESCNH
This study aims to develop a tool for hospitals to self-assess the implementation of the European Standards of Care for Newborn Health (ESCNH), standards defining best-practice procedures for neonatal care.
- Conditions
- Development of a Tool to Assess the Level of Implementing the European Standards of Care for Newborn Health, Testing of the Developed Self-assessment Tool in European Hospitals, Self-Assessment
- Trial name
- NCT06379828
- Testing
- Please note that this is an observational study; not applicable
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Global Foundation for the Care of Newborn Infants
Chronic Fatigue Syndrome, Fibromyalgia
Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans
Primary Hypothesis: Gulf War veterans will have an equal prevalence or mean level of the following medical and psychological conditions frequently reported in the literature compared to a control group of nondeployed veterans…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Post-Traumatic Stress Disorder, Neurologic Abnormalities
- Trial name
- NCT00032461
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
Mother Fetus Relations, Health Behavior
Examining the Effect of Breastfeeding Education Given to Mothers Based on Postpartum Awareness Practices on Breast Milk and Cortisol Hormone at the Newborn Circadian Level
In addition to being an easily accessible and ready-made food for babies in the first years of life, breast milk plays a major role in transmitting information about the time of day to newborn babies and therefore in the…
- Trial name
- NCT06240676
- Testing
- AWARENESS-BASED COGNITIVE THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Reproductive, Maternal, Newborn, and Child Health, Integrated, Community-Health Systems
Implementing an Integrated RMNCH Intervention by Community Health Workers in Achham and Dolakha: National Pilot
The investigators will conduct a cluster-controlled, stepped wedge implementation science trial of a bundled reproductive, maternal, neonatal, and child healthcare (RMNCH) delivery intervention within an approximate population of…
- Trial name
- NCT03371186
- Testing
- Community Health Worker, Continuous Surveillance, CB-Integrated Management of Newborn and Childhood Illness
- Where
- 2 sites in Nepal
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Possible
Mediterranean Fever, Colchicine Resistance
Study of Colchicine Resistance in Familial Mediterranean Fever
Five to 10% of familial mediterranean patients are considered colchicine-resistant (i.e. patients with a persistent inflammatory syndrome, despite taking the maximum tolerated dose of colchicine daily).
- Trial name
- COLCHI-RESIST (NCT05418686)
- Testing
- Capillary colchicine dosage in colchicine-resistant Familial Mediterranean Fever patients.
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neonatal Death, Perinatal Death
CHV-NEO: Community-based Digital Communication to Support Neonatal Health
Neonatal mortality (defined as death in the first 28 days of life) remains unacceptably high in sub-Sarahan Africa. The concentrated risk of neonatal illness in the first weeks of life and its potential to rapidly deteriorate…
- Trial name
- NCT05187897
- Testing
- CHV-NEO
- Where
- Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Washington
Defect, Congenital Heart, Arrhythmia
Relationship Between Functional Health Status and Ventricular Performance After Fontan--Pediatric Heart Network
The purpose of this cross-sectional study was to determine the interrelationships between health status and measures of cardiac performance in children 6 to 18 years of age with congenital heart disease who have undergone a…
- Trial name
- NCT00132782
- Volunteers
- 546 people
- Sponsor
- Carelon Research