Clinical trials: Neonatal Intensive Care
Infant Behavior
Stress Level, Skin Moisture and Physiological Parameters in the First Bath of Newborns
Objectıve: The aim of this study was to determine the effect of wipe (WG), shower (SG) and tub bath (TG) on stress level, skin moisture and physiological parameters used during the first bath in newborns hospitalized in the…
- Trial name
- NCT07109908
- Testing
- Wiping Bath, Wrapping Bath, Showering Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Infant, Premature
The Impact of Implementing NIDCAP on Preterm Infants in the NICU
The purpose of this study is to evaluate the impact of the NIDCAP program of individualized patient consultation on the neurobehavioral organization of transported preterm infants in the NICU.
- Trial name
- NCT00179933
- Testing
- Newborn Individualized Assessment Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Infant Development, Preterm Birth
Auditory Environment by Parents of Preterm Infants
Data on parent-infant physical closeness and infants' auditory environment will be collected among preterm infants when they are at gestational age of 32 to 34 weeks.
- Conditions
- Infant Development, Preterm Birth, Language Development
- Trial name
- APPLE (NCT04826978)
- Testing
- Auditory environment
- Volunteers
- 116 people
- Sponsor
- Turku University Hospital
Bloody Stool, Necrotizing Enterocolitis
a Clinical Risk Score to Predict Bloody Stool in Neonates
Bloody stool is a main focus in non-neonatal intensive care unit ward, and it is one of the risk factors in neonates with subsequent necrotizing enterocolitis(NEC) and usually lead to longed duration of hospitalization.
- Trial name
- NCT05055817
- Testing
- bloody stool group, non-bloody stool group
- Where
- China
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Preterm Infant, Premature Birth
The Effect of Tub vs Sponge Bathing on the Comfort of Premature Infants
The integumentary system protects the underlying body from the external environment, such as shocks, temperature, ultraviolet radiation, chemicals, and other threats.
- Trial name
- ComfortNEO (NCT03796312)
- Testing
- Tub Bathing, Sponge Bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Akdeniz University
Newborn Diseases, Breast Milk Collection
Sensory Mindfulness for NICU Mothers: Effects on Breast Milk, Well-Being, and Stress
Abstract Background: Breast milk is the optimal source of nutrition for infant growth and development and provides important physical and psychological benefits for mothers.
- Conditions
- Newborn Diseases, Breast Milk Collection, Well-being, MİNDFULNESS
- Trial name
- NCT07346339
- Testing
- Sensory Mindfulness Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Neonatal Disease
Neonatal Admission in Assuit University Children Hospital
There are many causes of admission of neonates in Neonatal Intensive Care Unit.So knowing such causes and their outcomes will give us knowledge about different risk factors of each disease and the prognosis of each cause.
- Trial name
- NCT04279301
- Volunteers
- 120 people
- Sponsor
- Assiut University
Complex Congenital Heart Disease
Noninvasive Measurement of the Cerebral Autoregulation in Neonates and Infants With Complex Congenital Heart Disease
Feasibility of non-invasive cerebral autoregulation measurement at the PICU and impact of changes in oxygen supply
- Trial name
- NCT04810013
- Testing
- non-invasive measurement of cerebral autoregulation
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Preterm Birth, Parent-Child Relations
Epigenetics and Protective Factors in the Preterm Infant
Preterm infants (PT) spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to unfavorable conditions with different effects on child development including long-term alterations in…
- Conditions
- Preterm Birth, Parent-Child Relations, Epigenetics
- Trial name
- EPIC (NCT04804280)
- Testing
- DNA methylation of target genes, Functional Magnetic Resonance Imaging (fMRI) acquisition
- Where
- Italy
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Infant, Premature, Diseases, Mothers
Home Support for Mothers Whose Premature Infants
Premature births are a challenging process for parents in many ways. Especially after the treatment and care in the hospital, they are concerned about whether they will be able to provide adequate care for their baby at home.
- Trial name
- NCT04741672
- Testing
- Providing guidance after discharge routine procedure and calling one week after discharge., Discharge routine procedure.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infant, Premature, Diseases
Probiotics On Resistant Bacteria Colonization In Preterm Receiving Antibiotics
In this study, the investigators investigated the effect of probiotic use on colonization of resistant microorganisms in newborn preterm infants receiving antibiotics.
- Trial name
- NCT02178267
- Testing
- Lactobacillus reuteri (biogai AB, Sweden)
- Volunteers
- 51 people
- Sponsor
- Baskent University
Infant Development, Patient Comfort
Effect Of Early Intervention Program Applied To Premature Infants
Purpose: This study was conducted to evaluate the effect of singing a lullaby with compassionate touch on early comfort and later on development of developmental support program in premature infants in the neonatal intensive care…
- Conditions
- Infant Development, Patient Comfort, Nursing Caries, Premature Infant Disease
- Trial name
- NCT06191757
- Testing
- supported with the developmental support program
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pain, Postoperative, Pain
Intravenous Acetaminophen For Postoperative Pain in the Neonatal Intensive Care Unit
The goal of this pilot randomized clinical trial is to determine the effect of the addition of IV acetaminophen to opioid-based pain regimes for infants admitted to the neonatal intensive care unit (NICU) after surgery.
- Trial name
- IVA POP NICU (NCT05678244)
- Testing
- Acetaminophen
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McMaster Children's Hospital
Premature Birth
Developmental Care Program in Neonatal Intensive Care Unit
This project is a Randomised Clinical Trial that includes a family centred education intervention and/or non-directive active listening counselling intervention with families of preterm infants at risk for sensori-motor disorders.
- Trial name
- CIN (NCT05573945)
- Testing
- Family Education and Active Listening, Family Education
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Pisa
Sickle Cell Disease, Glomerular Hyperfiltration
Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care
Background: Sickle cell disease is a genetic disorder of haemoglobin (which carries oxygen in red blood cells). The shape of sickle cell-patients' red blood cells is abnormal.
- Conditions
- Sickle Cell Disease, Glomerular Hyperfiltration, Sickle Cell Nephropathy, Vaso-Occlusive Crises
- Trial name
- PHEDREA (NCT07246265)
- Testing
- Injection of iohexol for glomerular filtration rate (GFR) measurement
- Where
- 6 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Bacterial Transmission Surveillance, Neonatal Intensive Care Unit
Bacterial Transmission Dynamics Study
Infections with multiply antibiotic-resistant bacteria represent a major cause of preventable morbidity and mortality amongst hospitalized neonates worldwide.
- Conditions
- Bacterial Transmission Surveillance, Neonatal Intensive Care Unit, Drug Resistance
- Trial name
- BTS (NCT02401204)
- Testing
- Longitudinal surveillance study
- Where
- Thailand
- Volunteers
- 97 people
- Sponsor
- University of Oxford
Leukemia
Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
RATIONALE: Monoclonal antibodies such as gemtuzumab ozogamicin can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells.
- Trial name
- AML-19 (NCT00091234)
- Testing
- gemtuzumab ozogamicin
- Where
- 45 sites in Belgium, Italy and 1 more
- Volunteers
- 279 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Premature Birth
Family Integrated Care (FICare) in Level II NICUs
In Alberta, nearly one in every twelve babies is born too soon (preterm). Preterm babies are at greater risk for breathing and feeding problems, as well as infections, than babies born on their due date (full term).
- Trial name
- FICare (NCT02879799)
- Testing
- Implement Family Integrated Care
- Where
- 10 sites in Canada
- Volunteers
- 765 people
- Sponsor
- University of Calgary
Anemia
NeoSpHb Study: Can a Painless Device Detect Anaemia in Babies Without Blood Tests? A Study in the Neonatal Intensive Care Unit (NICU)
The goal of this study is to evaluate the diagnostic performance and feasibility of non-invasive spectrophotometric haemoglobin (SpHb) measurement for detecting anaemia in infants admitted to the Neonatal Intensive Care Unit…
- Trial name
- NeoSpHb (NCT07788703)
- Testing
- Spectrophotometry hemoglobin
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya