Clinical trials: Neonatal Jaundice
Hyperbilirubinemia
Safety and Pharmacology of Stanate
The purpose of this study is to evaluate the effect and safety of Stanate (stannsoporfin) in infants who are at risk for an exchange transfusion and meet the criteria of the protocol.
- Trial name
- NCT00115544
- Testing
- Stanate
- Where
- Vietnam
- Volunteers
- 55 people
- Sponsor
- InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Exclusive Breastfeeding Rates, Neonatal Jaundice
BEST ABCs: Benefits and Effectiveness of Support Offered Through A Breastfeeding Clinic Study
Currently, healthy mothers willing to breastfeed their babies are discharged from the hospital on an average 2 days after a vaginal delivery or 3.5 days after a C-section, at a time where breastfeeding is far to be well…
- Trial name
- BEST ABCs (NCT02043119)
- Testing
- Breastfeeding Clinic
- Where
- Canada
- Volunteers
- 472 people
- Sponsor
- Ottawa Hospital Research Institute
Vascular Filling, Newborn
Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life
At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the…
- Conditions
- Vascular Filling, Newborn, Weight Loss, Jaundice
- Trial name
- PERLE (NCT07243054)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Neonatal Hyperbilirubinemia, Jaundice, Neonatal
Broad Band Emission LED Phototherapy Source Versus Narrow Band
Phototherapy is the most frequently used treatment in neonatology when serum bilirubin levels exceed physiological limits. Light-emitting diodes (LEDs) are become routinely used for phototherapy in neonates with…
- Trial name
- NCT05257369
- Testing
- Blue-Green LED photoherapy
- Where
- Armenia
- Volunteers
- 110 people
- Sponsor
- Erebouni Medical Center
Infant, Newborn, Jaundice
Prediction of Jaundice in Term Infants
The objective of this study was to describe total bilirubin production in healthy term infants as a means of understanding the differences in jaundice pigment production associated with various common clinical circumstances.
- Trial name
- NCT01203410
- Where
- 13 sites in United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Newborn Jaundice
Newborn Abdominal Massage to Prevent Hyperbilirubinemia
The proposed study will incorporate an intervention previously un-studied in the US healthcare setting for prevention of hyperbilirubinemia
- Trial name
- NCT05282394
- Testing
- Abdominal massage, Reading
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Digestive
Determinants of Digestive Morbidity in Neonatal Jaundice
Objective To explore the factors associated with adverse digestive system outcomes in neonates with jaundice. Methods A retrospective analysis was conducted on clinical data of hospitalized neonates admitted to the Department of…
- Trial name
- NCT07475624
- Testing
- Observation (Retrospective Cohort Study)
- Where
- China
- Volunteers
- 3,218 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Umbilical Cord
Timing of Umbilical Cord Clamping: One to Three Minutes vs. After Cessation of Cord Pulsation
The timing of umbilical cord clamping has been widely discussed in the scientific community. As part of the worldwide strategies to reduce childhood iron deficiency anemia, the incorporation of late clamping (at least one minute…
- Trial name
- CORD (NCT03844490)
- Testing
- CESSATION OF CORD PULSE, CONTROL
- Where
- Brazil
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Cerebral Palsy
Improvement in Gross Motor Function and Muscle Tone in Children With Cerebral Palsy Related to Neonatal Icterus
The purpose of this study is to evaluate the safety and effectiveness of stem cells for cerebral palsy related to neonatal icterus
- Trial name
- NCT03123562
- Testing
- Stem cell transplantation
- Where
- Vietnam
- Volunteers
- 25 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Newborn Jaundice
Assessment of Neonatal Hyperbilirubinemia by NeoprediX B.1 Algorithm
Due to actual standard of neonatal care bilirubin is monitored in neonates several times after birth to avoid hyperbilirubinemia.
- Trial name
- Bili-PrediX1 (NCT05121311)
- Testing
- NeoprediX B1 algorithm
- Where
- 2 sites in Germany
- Volunteers
- 455 people
- Sponsor
- NeoPredix AG
Neonatal Jaundice
Effect of Vitamin D Supplementation as Adjuvant Therapy in Neonatal Jaundice in Combination With Phototherapy
Neonatal jaundice frequently occur during initial week of life. Neonatal jaundice is one of the leading causes of hospital admission and readmission.
- Trial name
- NCT06650293
- Testing
- Vitamin D
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Muhammad Aamir Latif
End Tidal Carbon Monoxide Excretion as a Diagnostic Tool for Hemolysis in the Newborn, Neonatal Jaundice
End Tidal Carbon Monoxide (ETCO): - A Tool to Aid Identification of Neonatal Hemolysis
The purpose of this study is to evaluate if adding a noninvasive testing of End Tidal Carbon Monoxide with a FDA approved device will help improve management of jaundice in the Neonates by reducing the number of lab draws, Coombs…
- Conditions
- End Tidal Carbon Monoxide Excretion as a Diagnostic Tool for Hemolysis in the Newborn, Neonatal Jaundice, End Tidal Carbon Monoxide
- Trial name
- NCT05475223
- Testing
- End Tidal Carbon Monoxide Value
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Evaluation of a Smartphone Based Optical Diagnostic Tool for Neonatal Jaundice
Neonatal jaundice is a common and most often harmless condition. However, when unrecognized it can be fatal or cause serious brain injury. Three quarters of these deaths are estimated to occur in the poorest regions of the world.
- Trial name
- NCT03007563
- Testing
- bilirubin concentration estimation from smartphone pictures, bilirubin concentration measured in standard blood samples, bilirubin concentration measured by transcutaneous device
- Where
- 2 sites in Norway
- Volunteers
- 342 people
- Sponsor
- St. Olavs Hospital
Jaundice, Neonatal
Evaluation of a Smartphone Based Screening Tool for Neonatal Jaundice in Surabaya, Indonesia
A cross-sectional conductive study aiming to evaluate the accuracy of a novel smartphone application that estimates bilirubin levels in newborns in Surabaya.
- Trial name
- NCT05623566
- Testing
- Picterus Jaundice Pro
- Where
- 3 sites in Indonesia
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Picterus AS
Jaundice, Neonatal
Validation of an Innovative Neonatal Jaundice Detection System (Picterus) in Indonesia
The long-term goal of this project is to establish Picterus as a permanent tool to detect NNJ in the healthcare services of Indonesia.
- Trial name
- NCT05630495
- Testing
- Picterus Jaundice Pro
- Where
- 2 sites in Indonesia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Picterus AS
Bilirubinemia, Newborn Jaundice
Effect of Repositioning Frequency Neonates Receiving Phototherapy
Purpose: The present study was conducted to determine the effect of repositioning frequency during phototherapy on bilirubin level and neonates comfort.
- Trial name
- NCT05692648
- Testing
- Supine position group, Hourly position change group, Control Group (2-hour position change)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Intrahepatic Cholestasis of Pregnancy
Different Effects of Delayed Clamping on Neonatal Bilirubin Levels Between Pregnant Women With Intrahepatic Cholestasis of Pregnancy and Normal Pregnant Women
Objective:The aim of this study was to investigate the relationship between delayed cord clamping and neonatal bilirubin levels in pregnant women with intrahepatic cholestasis of pregnancy.
- Trial name
- NCT05637151
- Testing
- clamp time of umbilical
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Neonatal Jaundice, Phototherapy Complication
Continuous Versus Intermittent Phototherapy in Treatment of Neonatal Jaundice
One of the most common diseases in the neonatal period is indirect hyperbilirubinemia (IHB). After phototherapy was discovered accidentally in 1958, it has been used as the most effective treatment method for IHD for more than 60…
- Trial name
- NCT06386731
- Testing
- Intermittent Phototherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Preterm Birth, Low Birth Weight
Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns
This study focuses on understanding the conditions that affect newborn health and survival from pregnancy to the first weeks of life at the Isidro Ayora Hospital.
- Conditions
- Preterm Birth, Low Birth Weight, Intrauterine Growth Restriction (IUGR), Perinatal Asphyxia
- Trial name
- UCE (NCT06653374)
- Testing
- Infant, Premature
- Where
- Ecuador
- Volunteers
- 26,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Biliary Atresia
Evaluation of Immune Function in Biliary Atresia Children With Prolonged Jaundice
Null hypothesis of this study: Biliary atresia patients with cholestatic jaundice do not have systemic immunity defect.
- Trial name
- NCT00155194
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital